Journals / İnönü üniversitesi Sağlık Hizmetleri Meslek Yüksek Okulu Dergisi / 2021 / Cilt: 9 - Sayı: 1

Effect of Inflammatory Markers in Routine Hemogram on Prognosis in Patients with Sudden Hearing Loss

ANİ İŞİTME KAYIPLI HASTALARDA RUTİN HEMOGRAM İÇİNDEKİ İNFLAMATUAR MARKIRLARIN PROGNOZA ETKİSİ

Pages
130–139
Publication Date
2022-10-19
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

These parameters can be used as a new marker in the diagnosis and prognosis of SHL with a routine and inexpensive test performed at the diagnosis stage of the disease.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:This study evaluates the effect of hemogram results on the degree and prognosis of patients with sudden hearing loss (SHL). 70 of 325 patients diagnosed with SHL in our clinic between 2015-2020 were included in the study.
📊
Key Findings & Data:The patients were divided into 3 groups according to the degree of hearing loss.
💡
Conclusion & Impact:These parameters can be used as a new marker in the diagnosis and prognosis of SHL with a routine and inexpensive test performed at the diagnosis stage of the disease.
🔬Design:Research Article
📍Scope:2015-2020 Verileri
⚙️Variables:Ani işitme kaybı · hemogram · platelet

Abstract

This study evaluates the effect of hemogram results on the degree and prognosis of patients with sudden hearing loss (SHL). 70 of 325 patients diagnosed with SHL in our clinic between 2015-2020 were included in the study. Routine hemogram parameters and hearing tests of the patients before treatment were examined. A control group was formed from healthy individuals with similar characteristics. The patients were divided into 3 groups according to the degree of hearing loss. In our study, hemoglobin, mean platelet volume (MPV), platelet, neutrophil, neutrophil lymphocyte ratio (NLR) and platelet lymphocyte ratio (PLR), platelet x neutrophil / lymphocyte (PxN/L) values were compared. Statistical difference was found between the group with SHL and the control group in terms of hemoglobin, neutrophil, lymphocyte, MPV, PLO, NLO, PxN/L values. These parameters can be used as a new marker in the diagnosis and prognosis of SHL with a routine and inexpensive test performed at the diagnosis stage of the disease.

Özet

Bu çalışma; ani işitme kayıplı (AİK) hastaların hemogram sonuçlarının hastalığın derecesi ve prognozuna etkisini değerlendirmektedir. Çalışmaya, 2015-2020 yılları arasında kliniğimizde AİK tanısı konulan 325 hastanın 70’i dâhil edildi. Hastaların tedavi öncesindeki rutin hemogram parametreleri ve işitme testleri incelendi. Hastalar ile benzer özelik taşıyan sağlıklı bireylerden kontrol gurubu oluşturuldu. Hastalar işitme kaybı derecesi kaybına göre de 3 guruba ayrıldı. Çalışmamızda; hemoglobin, trombosit hacmi (MPV), platelet, nötrofil, nötrofil lenfosit oranı (NLO) ve platelet lenfosit oranı (PLO), platelet x nötrofil / lenfosit (PxN/L) değerleri karşılaştırıldı. AİK’lı gurup ile kontrol gurubu arasında hemoglobin, nötrofil, lenfosit, MPV, PLO, NLO, PxN/Ldeğerleri açısından istatiksel fark saptandı. Hastalığın tanı aşamasında yapılan rutin ve ucuz bir tetkik ile AİK tanısında ve prognozunda bu parametreler yeni bir belirteç olarak kullanılabilir.

🔖

Cite This Article

CENGİZ, D. U., TAN, M., BAYINDIR, T., KARAKAŞ, O. (2022). Effect of Inflammatory Markers in Routine Hemogram on Prognosis in Patients with Sudden Hearing Loss. İnönü üniversitesi Sağlık Hizmetleri Meslek Yüksek Okulu Dergisi, Cilt: 9 - Sayı: 1, 130–139. https://ajindex.com/articles/548280

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (10)

  1. Akopuz, A., Turan, V., Özcan, A., Kopuz, Y., Toz, E., Kurt, S. (2016). A novel marker for the assessment of the treatment result in pelvic inflammatory disease. Minerva ginecologica, 68(2), 117-123.
  2. Balta, S., Demirkol, S., Küçük, U. (2013). The platelet lymphocyte ratio may be useful inflammatory indicator in clinical practice. Hemodialysis International, 4(17), 668-669.
  3. Boyraz, İ., Koç, B., Boyacı, A., Tutoğlu, A., Sarman, H., Özkan, H. (2014). Ratio of neutrophil/lymphocyte and platelet/lymphocyte in patient with ankylosing spondylitis that are treating with anti-TNF. International journal of clinical and experimental medicine, 7(9), 2912. Braekkan, S., Mathiesen, E., Njølstad, I., Wilsgaard, T., Størmer, J., Hansen, J. (2010). Mean platelet volume is a risk factor for venous thromboembolism: the Tromsø study. Journal of Thrombosis and Haemostasis, 8(1), 157-162.
  4. Cadoni, G., Agostino, S., Manna, R., De Santis, A., Fetoni, A. R., Vulpiani, P.,. Ottaviani, F. (2003). Clinical associations of serum antiendothelial cell antibodies in patients with sudden sensorineural hearing loss. The Laryngoscope, 113(5), 797-801.
  5. Caligiuri, G., Nicoletti, A. (2006). Lymphocyte responses in acute coronary syndromes: lack of regulation spawns deviant behaviour. In: The University of Chicago Press.
  6. Chau, J. K., Lin, J. R., Atashband, S., Irvine, R. A., Westerberg, B. D. (2010). Systematic review of the evidence for the etiology of adult sudden sensorineural hearing loss. The Laryngoscope, 120(5), 1011-1021.
  7. Chu, S., Becker, R., Berger, P., Bhatt, D., Eikelboom, J., Konkle, B.,. Berger, J. (2010). Mean platelet volume as a predictor of cardiovascular risk: a systematic review and meta‐analysis. Journal of Thrombosis and Haemostasis, 8(1), 148-156.
  8. Cook, E. J., Walsh, S. R., Farooq, N., Alberts, J. C., Justin, T. A., Keeling, N. J. (2007). Post-operative neutrophil–lymphocyte ratio predicts complications following colorectal surgery. International Journal of Surgery, 5(1), 27-30.
  9. Coppinger, J. A., Cagney, G., Toomey, S., Kislinger, T., Belton, O., McRedmond, J. P.,. Maguire, P. B. (2004). Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions. Blood, 103(6), 2096-2104.
  10. Durmuş, K., Terzi, H., Karataş, T. D., Doğan, M., Uysal, I. Ö., Sencan, M.,. Altuntaş, E. E. (2016). Assessment of hematological factors involved in development and prognosis of idiopathic sudden se