Journals / İnfeksiyon Dergisi / 1996 / Cilt: 10 - Sayı: 3

Cytokine levels in acute and chronic viral hepatitis

Akut ve kronik viral hepatitlerde sitokin düzeyleri

Pages
253–258
Publication Date
2022-10-17
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

However, hepatitis C cases showed TNF-a levels a little higher than those of normal controls.

📌 3 Key Takeaways

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Objective & Hypothesis:To determine the interaction of different cytokines SİL-2R, TNF-a, IL-6 ve IL-1a levels were measured with ELISA in 29 patients wth acute viral hepatitis, 11 patients with chronic viral hepatitis and 15 healthy individuals.
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Key Findings & Data:Serum SİL-2R, TNF-a, IL-6 levels were higher and serum IL-1a was lower in the acute viral hepatitis cases.
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Conclusion & Impact:However, hepatitis C cases showed TNF-a levels a little higher than those of normal controls.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

To determine the interaction of different cytokines SİL-2R, TNF-a, IL-6 ve IL-1a levels were measured with ELISA in 29 patients wth acute viral hepatitis, 11 patients with chronic viral hepatitis and 15 healthy individuals. Serum SİL-2R, TNF-a, IL-6 levels were higher and serum IL-1a was lower in the acute viral hepatitis cases. In chronic acute viral hepatitis cases due to hepatitis B virus no TNF-a was found. However, hepatitis C cases showed TNF-a levels a little higher than those of normal controls.

Özet

Yirmidokuz akut viral hepatit ve 11 kronik aktif viral hepatit hastasında ve 15 normal kişide SİL-2R, TNF-a, IL-6 ve IL-1a düzeyleri EUSA ile ölçülerek sonuçlar kendi aralarında, normal grupla ve biyokimyasal değerlerle karşıiaştırıimıştır. Akut viral hepatit (HAV, HBV, HCV) olguların serumlarında SİL-2R, TNF-a, IL-6 yüksek; IL-1a düşük olarak saptanmıştır. Kronik aktif viral hepatitlerde ise SİL-2R yüksek IL-6 ve L-1a düşük olarak saptanırken, HBV'ye bağlı kronik aktif hepatitte TNF-a hiç saptanamamış, HCV'de normale göre hafif yüksek olduğu görülmüştür.

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Cite This Article

KÖSE, Ş., BATUR, Y., KOKULUDAĞ, A., SİN, A., SEBİK, F., KABAKÇI, T., TERZİOĞLU, E. (2022). Cytokine levels in acute and chronic viral hepatitis. İnfeksiyon Dergisi, Cilt: 10 - Sayı: 3, 253–258. https://ajindex.com/articles/547183

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