AI Summary & Key Takeaways
AI InsightAs a result, it was observed that the concentrations of IgA were correlated with glycemic control, and abnormal concentrations of other immunglobulins were found in patients who had impaired glycemic control.
📌 3 Key Takeaways
Abstract
Abnormal serum IgA levels were seen in 49 % of insulin-dependent diabetes mellitus (IDDM) patients and 52 % of non-insulin-dependent diabetes mellitus (NIDDM) patents. Abnormal concentrations of IgG were found to be lower (10.2 % of IDDM patients and 12.3 % of NIDDM patients). In contrast to IgA and IgG concentrations, the concentration of IgM were found to be lower in 43.4 % of all the diabetics as compared with the control group. It was seen that there was a correlation between IgA and fructosamine, HbAlc and albumin. As a result, it was observed that the concentrations of IgA were correlated with glycemic control, and abnormal concentrations of other immunglobulins were found in patients who had impaired glycemic control.
Özet
insuline bağımlı diabetes mellitus (IDDM)'lu hastaların % 49'unda, insûline bağımsız diabetes mellitus (NIDDM)'lu hastaların % 52'sinde anormal serum IgA yoğunlukları görüldü. Anormal IgG yoğunlukları ise daha düşük orandaydı (IDDM'ta % 10.2, NIDDM'ta % 12.3). IgA ve IgG'nin tersine, IgM yoğunlukları toplam diyabetiklerin % 43.3ünde kontrollere göre daha düşük bullundu. IgA'nın fruktozamin HbAlc, ve albumin ile korelasyon gösterdiği saptandı. Sonuç olarak IgA konsantrasyonlarının glisemik kontrol ile ilişkili oduğu ve glisemik kontrolün bozuk olduğu hastalarda diğer immunglobulinlerde de anormal yoğunlukların olduğu görüldü.