Journals / İnfeksiyon Dergisi / 1998 / Cilt: 12 - Sayı: 1

The comparison of the efficacy of vancomycin and trimethoprim-sulfamethoxazole on Staphylococcus aureus

Staphylococcus aureus'a karşı vankomisin ve trimetoprim-sulfametaksazol etkinliğinin karşılaştırılması

Pages
39–41
Publication Date
2022-10-17
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

For all MRSA and MSSA strains MIC50 Va was found as 0.5 ugr/ml and MIC50 TMP-SMX was in the 1/19 - 2/38 ugr/ml range.

📌 3 Key Takeaways

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Objective & Hypothesis:Vancomycin (Va) and trimethoprim-sulfamethoxazole (TMP-SMX) susceptibilities of 178 Staphylococcus aureus strains isolated from various clinical samples were studied with disk-diffusion and microbroth dilution methods.
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Key Findings & Data:All of the strains were found susceptible to Va with disk-diffusion method. % 91.4 of MRSA strains and % 94.5 of MSSA strains were susceptible to TMP-SMX.
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Conclusion & Impact:For all MRSA and MSSA strains MIC50 Va was found as 0.5 ugr/ml and MIC50 TMP-SMX was in the 1/19 - 2/38 ugr/ml range.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Vancomycin (Va) and trimethoprim-sulfamethoxazole (TMP-SMX) susceptibilities of 178 Staphylococcus aureus strains isolated from various clinical samples were studied with disk-diffusion and microbroth dilution methods. All of the strains were found susceptible to Va with disk-diffusion method. % 91.4 of MRSA strains and % 94.5 of MSSA strains were susceptible to TMP-SMX. For all MRSA and MSSA strains MIC50 Va was found as 0.5 ugr/ml and MIC50 TMP-SMX was in the 1/19 - 2/38 ugr/ml range.

Özet

Çeşitli klinik örneklerden soyutlanan 178 Staphylococcus aureus susunun vankomisin (Va) ve trimetoprim-sulfametaksazol (TMP-SMX) duyarlılıkları disk difüzyon ve buyon mikrodilüsyon yöntemleriyle incelendi. Tüm suşlar disk difüzyon yöntemiyle Va'e duyarlı bulundu. TMP-SMX'e duyarlılık, metisiline duyarlı Staphylococcus aureus (MRSA) suşlarında % 91.4, metisiline dirençli olanlarda (MSSA) % 94.5 düzeyinde saptandı. Tüm suşlar için Va MİK50 değeri 0.5 ugr/ml, TMP-SMX MİK50 değeri 1/19 - 2/38 ugr/ml arasında saptandı.

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Cite This Article

SONGUR, M., YÜCE, A., SAYAN, M., YULUĞ, N. (2022). The comparison of the efficacy of vancomycin and trimethoprim-sulfamethoxazole on Staphylococcus aureus. İnfeksiyon Dergisi, Cilt: 12 - Sayı: 1, 39–41. https://ajindex.com/articles/547087

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