Journals / İnfeksiyon Dergisi / 1998 / Cilt: 12 - Sayı: 3

The susceptibility of shigella strains to antimicrobial agents

Shigella suşlarının antimikrobiyal ajanlara duyarlılıkları

Pages
381–383
Publication Date
2022-10-17
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It is concluded that Shigella strains have acquired resistance to routine antibiotics used in the treatment of Shigellosis and that therapy should be carried out according to the antibiotic susceptibility tests.

📌 3 Key Takeaways

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Objective & Hypothesis:This study aimed at determining the antibiotic susceptibility of Shigella strains.
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Key Findings & Data:Sixty-seven Shigella strains were isolated from stool specimens in the Laboratory of Microbiology Department, Medical School, Pamukkale University, in 1995 and 1996.
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Conclusion & Impact:It is concluded that Shigella strains have acquired resistance to routine antibiotics used in the treatment of Shigellosis and that therapy should be carried out according to the antibiotic susceptibility tests.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

This study aimed at determining the antibiotic susceptibility of Shigella strains. Sixty-seven Shigella strains were isolated from stool specimens in the Laboratory of Microbiology Department, Medical School, Pamukkale University, in 1995 and 1996. The isolates were identified biochemically and serologically. Thirty four per cent of 67 Shigella strains was S. flexneri: 23 % S. sonnei, 8 % S. dysenteriae and 2 % S. boydii. The antibiotic susceptibility tests were by using disk diffusion method. Sixty per cent of 67 isolates was susceptible to ampicillin, 84 % to amoxicillin-clavulanate, 84 % to sulbactam-ampicillin, 54 % to trimethoprim-sulfamethoxazole, 67 % to chloramphenicol, 40 % to tetracyline, 69 % to cephalothin, 96 % to gentamicin. All Shigella strains were susceptible to ceftriaxone, imipenem and ciprofloxacin. It is concluded that Shigella strains have acquired resistance to routine antibiotics used in the treatment of Shigellosis and that therapy should be carried out according to the antibiotic susceptibility tests.

Özet

Bu çalışmanın amacı, Shigella suşlarının antibiyotik duyarlılıklarını saptamaktır. 1995 ve 1996 yıllarında Pamukkale Üniversitesi Tıp Fakültesi Mikrobiyoloji Laboratuvan'nda dışkı kültürlerinden izole edilen 67 Shigella susunun türleri belirlenerek çeşitli antibiyotiklere karşı in vitro duyarlılıkları disk difüzyon yöntemiyle incelendi, izole edilen 67 sustan 34'ü S. flexneri. 23'ü S. sonnei. sekizi S. dysenteriae. ikisi S. boydu olarak bulundu. Bu suşların ampisiline % 60';; sulbaktam-ampisiline % 84'ü; amoksisilin-klavulonata % 84'ü; trimetoprim-sülfametoksazole % 54'ü; kloramfenikole % 67'si; tetrasikline % 40'; sefaletine % 69'u; gentamisine % 96'sı duyarlı bulunurken, tüm suşlar seftriakson, imipenem, siprofloksasine % 100 duyarlı bulundu. Shigelloz tedavisinde rutin kullanılan birçok antibiyotiğe etkenin direnç kazanmış olduğu ve tedavinin antibiyotik duyarlılık testlerine göre yönlendirilmesi gerektiği sonucuna varıldı.

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Cite This Article

KALELİ, İ., ÖZEN, N., AKŞİT, F., ŞENGÜL, M. (2022). The susceptibility of shigella strains to antimicrobial agents. İnfeksiyon Dergisi, Cilt: 12 - Sayı: 3, 381–383. https://ajindex.com/articles/547061

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