Journals / İnfeksiyon Dergisi / 1998 / Cilt: 12 - Sayı: 2

The in vitro activity of meropenem on Pseudomonas aeruginosa, Klebsiella pneumoniae and Aacinetobacter species

Meropenemin Pseudomonas aeruginosa, Klebsiella pneumoniae ve Acinetobacter kökenlerine in vitro etkinliği

Pages
161–164
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Totally 270 P. aeruginosa and 62 Acinetobacte strains isolated from patients with nosocomial infection were enrolled the study. $MİK_{50}$ and $MİK_{90}$ values of meropenem against these strains were found 1 $mu$g/ml and 16$mu$g/ml (range 0.06-256 $mu$g/ml), in P. aeruginosa. 0.06 $mu$g/ml and 0.25 $mu$g/ml (range 0.06-0.2 $mu$g/ml) in K. pneumoniae and 1 $mu$g/ml and 8 $mu$g/m (range 0.06-0.32 $mu$g/ml) in Acinetobacter spp, respectively.

📌 3 Key Takeaways

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Objective & Hypothesis:Efficacy of meropenem against Pseudomonas aeruginosa.
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Key Findings & Data:Klebsiella pneumoniae and Acinetobacter species were investigated by agar dilution method.
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Conclusion & Impact:Totally 270 P. aeruginosa and 62 Acinetobacte strains isolated from patients with nosocomial infection were enrolled the study. $MİK_{50}$ and $MİK_{90}$ values of meropenem against these strains were found 1 $mu$g/ml and 16$mu$g/ml (range 0.06-256 $mu$g/ml), in P. aeruginosa. 0.06 $mu$g/ml and 0.25 $mu$g/ml (range 0.06-0.2 $mu$g/ml) in K. pneumoniae and 1 $mu$g/ml and 8 $mu$g/m (range 0.06-0.32 $mu$g/ml) in Acinetobacter spp, respectively.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Efficacy of meropenem against Pseudomonas aeruginosa. Klebsiella pneumoniae and Acinetobacter species were investigated by agar dilution method. Totally 270 P. aeruginosa and 62 Acinetobacte strains isolated from patients with nosocomial infection were enrolled the study. $MİK_{50}$ and $MİK_{90}$ values of meropenem against these strains were found 1 $mu$g/ml and 16$mu$g/ml (range 0.06-256 $mu$g/ml), in P. aeruginosa. 0.06 $mu$g/ml and 0.25 $mu$g/ml (range 0.06-0.2 $mu$g/ml) in K. pneumoniae and 1 $mu$g/ml and 8 $mu$g/m (range 0.06-0.32 $mu$g/ml) in Acinetobacter spp, respectively.

Özet

Meropenemin hastane infeksiyonu etkeni olarak soyutlanan Pseudomonas aeruginosa. Klebsiella pneumoniae ve Acinetobacter türlerine in vitro etkinliğinin araştırılması amacıyla 270 P. aeruginosa ve 62 Acinetobacte kökeninin meropenem duyarlılıkları agar dilüsyon yöntemi ile incelendi. Meropenem için P. aeruginosa kökenlerinde$MİK_{50}$ 1 $mu$g/ml ve $MİK_{90}$ 16 $mu$g/ml (aralık 0.06-256 $mu$g/ml), K. pneumoniae kökenlerinde $MİK_{50}$ 0.06 $mu$g/ml ve $MİK_{90}$ 0.25 $mu$g/ml (aralık 0.06-0.2 $mu$g/ml) ve Acinetobacter türlerinde de MlK50 1$mu$g/ml ve $MİK_{90}$ 8 $mu$g/ml (aralık 0.06-0.2 $mu$g/ml) olarak belirlendi

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Cite This Article

ÖZKAN, F., HİLMİOĞLU, S., NAFİLE, B., HASSAN, A., ÖZİNEL, M. A., TÜNGER, A., ÇAVUŞOĞLU, C. (2022). The in vitro activity of meropenem on Pseudomonas aeruginosa, Klebsiella pneumoniae and Aacinetobacter species. İnfeksiyon Dergisi, Cilt: 12 - Sayı: 2, 161–164. https://ajindex.com/articles/547046

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