Journals / İnfeksiyon Dergisi / 1998 / Cilt: 12 - Sayı: 4

In vitro susceptibility of candida strains isolated from hemocultures to fluconazole

Kan kültürlerinden soyutlanan candida kökenlerinin flukonazole in vitro duyarlılığı

Pages
531–533
Publication Date
2022-10-17
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Of the C. tropicalis strains, 91% (21) were susceptible and 9% (2) were susceptible-dose dependent.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Between January 1996 and May 1997, in vitro susceptibility of a total of 60 Candida strains (27 C. albicans: 23 Ç. tropicalis and W C. parapsilosis) to fluconazole, which were isolated from haemocultures of non-neutropenic patients treated in several intansive care units at Ege University Hospital was studied by the macrodilution method ( M27-P ) of NCCLS.
📊
Key Findings & Data:Of the C. albicans strains, 93% (25) were susceptible (MIC < 8 $mu$g/ml) and 7% (2) susceptible-dose dependent (MIC 16-32 $mu$g/rnl) .
💡
Conclusion & Impact:Of the C. tropicalis strains, 91% (21) were susceptible and 9% (2) were susceptible-dose dependent.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Between January 1996 and May 1997, in vitro susceptibility of a total of 60 Candida strains (27 C. albicans: 23 Ç. tropicalis and W C. parapsilosis) to fluconazole, which were isolated from haemocultures of non-neutropenic patients treated in several intansive care units at Ege University Hospital was studied by the macrodilution method ( M27-P ) of NCCLS. Of the C. albicans strains, 93% (25) were susceptible (MIC < 8 $mu$g/ml) and 7% (2) susceptible-dose dependent (MIC 16-32 $mu$g/rnl) . Of the C. tropicalis strains, 91% (21) were susceptible and 9% (2) were susceptible-dose dependent.

Özet

Ege Üniversitesi Tıp Fakültesi Hastanesi, yoğun bakım ünitelerinde, Ocak 1996-Mayıs 1997 tarihleri arasında, nötropenisi olmayan, çeşitli hastalıkları nedeniyle izlenen, kandidoz kuşkulu hastaların kan kültürlerinden soyutlanan toplam 60 Candida kökeni (27 C. albicans. 23 C. tropicalis ve 10 C. parapsilosis) 'n/n flukonazole in vitro duyarlılığı "National Committee for Clinical Laboratory Standards" (NCCLS )'ın önerdiği makrodilüsyon yöntemi ( M27-P ) ile araştırıldı. C. albicans kökenlerinin %93 (25)' ü duyarlı (Minimal İnhibisyon Konsantrasyonu (M İ K) < 8 /$mu$g/ml), %7 (2)'si doza bağımlı duyarlı (MİK 16-32 y.g/ml) olarak saptandı. C. tropicalis kökenlerinin %91 (21)'i duyarlı, %9 (2)'u ise doza bağımlı duyarlı idi. C. parapsilosis kökenlerinde ise MİK değeri < 8 /$mu$g/ml (duyarlı) idi.

🔖

Cite This Article

ERMERTCAN, Ş., HİLMİOĞLU, S., İNCİ, R., TÜMBAY, E. (2022). In vitro susceptibility of candida strains isolated from hemocultures to fluconazole. İnfeksiyon Dergisi, Cilt: 12 - Sayı: 4, 531–533. https://ajindex.com/articles/547038

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...