Journals / İnfeksiyon Dergisi / 1999 / Cilt: 13 - Sayı: 4

Brucellosis and lipid peroxidation

Bruselloz ve lipit peroksidasyonu

Pages
493–495
Publication Date
2022-10-17
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The difference between the two groups was statistically significant (p

📌 3 Key Takeaways

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Objective & Hypothesis:Recent studies suggest that enhanced release of free oxygen radicals plays an important role in the pathogenesis of infections.
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Key Findings & Data:To investigate whether lipid peroxidation increases in brucellosis or not, plasma malondialdehyde (MDA) concentration was determined in healthy subjects and in patients with brucellosis.
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Conclusion & Impact:The difference between the two groups was statistically significant (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Recent studies suggest that enhanced release of free oxygen radicals plays an important role in the pathogenesis of infections. Free radicals cause important changes in cellular components as lipids and proteins, in cellular structure and functions. The most important effect of free radicals on lipid is lipid peroxidation. To investigate whether lipid peroxidation increases in brucellosis or not, plasma malondialdehyde (MDA) concentration was determined in healthy subjects and in patients with brucellosis. Mean plasma MDA concentration was 1.222±0.305 µmol/L for the brucellosis group and 0.576±0.182 µmol/L for the control group. The difference between the two groups was statistically significant (p

Özet

Son çalışmalar serbest oksijen radikallerinin salınımındaki artışın infeksiyonların patogenezinde önemli bir rol oynadığını göstermektedir. Serbest radikaller lipitler ve proteinler gibi hücre bileşenlerinde, hücre yapı ve fonksiyonlarında önemli değişikliklere neden olmaktadır. Serbest radikallerin lipitler üzerinde oluşturduğu en önemli olay lipit peroksidasyonudur. Brusellozda lipit peroksidasyonunun artıp artmadığını araştırmak için, sağlıklı kişilerde ve brusellozlu hastalarda plazma malondialdehit (MDA) düzeyleri belirlendi. Ortalama malondialdehit düzeyi bruselloz grubunda 1.222 ±0.305 µmol/L, kontrol grubunda 0.576±0.182 µmol/L olarak saptandı. İki grup arasındaki fark istatistiksel olarak anlamlıydı (p

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Cite This Article

ERBAY, A. R., BAYKAM, N., DOKUZOĞUZ, B., EREN, Ş., ERBAY, A. (2022). Brucellosis and lipid peroxidation. İnfeksiyon Dergisi, Cilt: 13 - Sayı: 4, 493–495. https://ajindex.com/articles/547005

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