Journals / İnfeksiyon Dergisi / 2000 / Cilt: 14 - Sayı: 1

In vitro fusidic acid susceptibility of Staphylococcus aureus strains isolated from various clinical specimens

Çeşitli klinik örneklerden soyutlanan Staphylococcus aureus kökenlerinin fusidik aside in vitro duyarlılığı

Pages
95–97
Publication Date
2022-10-17
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It is concluded that fusidic acid is an effective antibiotic against staphylococci.

📌 3 Key Takeaways

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Objective & Hypothesis:In this study, the antimicrobial activity of fusidic acid on Staphylocccus aureus strains was investigated by disk diffusion and microdilution methods.
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Key Findings & Data:The methicillin resistance and then fusidic acid susceptibility were determined in 140 S. aureus strains.
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Conclusion & Impact:It is concluded that fusidic acid is an effective antibiotic against staphylococci.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

In this study, the antimicrobial activity of fusidic acid on Staphylocccus aureus strains was investigated by disk diffusion and microdilution methods. The methicillin resistance and then fusidic acid susceptibility were determined in 140 S. aureus strains. To determine the diameter of inhibition zones and minimum inhibition concentration (MIC) range, the criteria of Comite' de l'Antibiogramme de la Societe Française de Microbiologie were used. The rate of susceptibility to fusidic acid, in which methicillin resistance was 6 %, was 98 %. Of these strains only three (2 %) were found to be intermediate susceptible. It is concluded that fusidic acid is an effective antibiotic against staphylococci.

Özet

Bu çalışmada Staphylococcus aureus kökenleri üzerine fusidik asidin antimikrobiyal etkinliğinin disk difüzyon ve mikrodilüsyon yöntemleri ile araştırılması amaçlandı. Toplam 140 S. aureus kökeninde metisilin direnci belirlendikten sonra bu kökenlerin fusidik aside karşı duyarlılıkları araştırıldı. Minimum inhibisyon konsantrasyonu (MİK) ve inhibisyon zon çapları Comite de l'Antibiogramme de la societe française de Microbiologie kriterlerine göre belirlendi. Metisilin direnci % 6 olan bu kökenlerin fusidik aside duyarlılık oranı %98 olarak saptandı. Sadece üç kökenin (% 2) fusidik aside orta derecede duyarlı olduğu görüldü. Bu çalışmanın sonucuna göre, stafilokok infeksiyonlarında fusidik asit etkili bir antibiyotiktir.

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Cite This Article

HOŞGÖR, M., ERAÇ, B., COŞAR, G., ERMERTCAN, Ş. (2022). In vitro fusidic acid susceptibility of Staphylococcus aureus strains isolated from various clinical specimens. İnfeksiyon Dergisi, Cilt: 14 - Sayı: 1, 95–97. https://ajindex.com/articles/546903

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