AI Summary & Key Takeaways
AI InsightThirty-five of 71 M. tuberculosis isolates were susceptible (MIC90, 1: 0.5 microg/ml), nine were intermediate susceptible (MIC90, 8:4 micro/ml), and 27 were resistant to amoxicillin-clavulanic acid.
📌 3 Key Takeaways
Abstract
The purpose of this study was to determine the in vitro susceptibility of Mycobacterium tuberculosis to amoxicillin-clavulanic acid and clarithromycin. The activities of amoxicillin-clavulanic acid and clarithromycin on 71 clinical isolates of M. tuberculosis were determined by using E-test. Fifty four of 71 M. tuberculosis isolates were susceptible (MIC90, 16 microg/ml) to clarithromycin. Thirty-five of 71 M. tuberculosis isolates were susceptible (MIC90, 1: 0.5 microg/ml), nine were intermediate susceptible (MIC90, 8:4 micro/ml), and 27 were resistant to amoxicillin-clavulanic acid.
Özet
Bu çalışmanın amacı, Mycobacterium tuberculosis'in amoksisilin-klavulanik asit ve klaritromisine in vitro duyarlılığını saptamak idi. Çeşitli klinik örneklerden soyutlanan 71 M. tuberculosis izolatının amoksisilin-klavulanik asit ve klaritromisine duyarlılığı E-test yöntemi ile araştırılmıştır. Klaritromisine karşı 54 izolat duyarlı (MIC90, 16 microg/ml); amoksisilin-klavulanik asite karşı 35 izolat duyarlı (MIC90, 1: 0.5 microg/ml), dokuz izolat orta derecede duyarlı (MIC90, 8: 4 microg/ml), 27 izolat dirençli (MİK90, > 32: 16 microg/ml) bulunmuştur.