Journals / İnfeksiyon Dergisi / 2001 / Cilt: 15 - Sayı: 2

Determination of the in vitro activity of several antimicrobial agents against blood culture isolates of Staphylococcus using the biomic system

Kan kültürlerinden soyutlanan Staphylococcus kökenlerinin antibiyotik duyarlılıklarının biomic sistemi ile saptanması

Pages
235–238
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

These results should be taken into account for initiating empirical therapy of bacteremia when staphylococci are suspected.

📌 3 Key Takeaways

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Objective & Hypothesis:The purpose of the present study was to determine the antibiotic susceptibility of staphylococci causing systemic infection.
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Key Findings & Data:The in vitro susceptibility of Staphylococcus aureus (45) and coagulase-negative staphylococci (CNS) (105) to vancomycin, erythromycin, amikacin, gentamicin and ciprofloxacin was determined by disk diffusion and BIOMIC system.
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Conclusion & Impact:These results should be taken into account for initiating empirical therapy of bacteremia when staphylococci are suspected.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The purpose of the present study was to determine the antibiotic susceptibility of staphylococci causing systemic infection. The in vitro susceptibility of Staphylococcus aureus (45) and coagulase-negative staphylococci (CNS) (105) to vancomycin, erythromycin, amikacin, gentamicin and ciprofloxacin was determined by disk diffusion and BIOMIC system. The resistance rates to methicillin were 65 % and 57 % in S. aureus and CNS, respectively. Resistance to vancomycin was not detected while higher rates of resistance against erythromycin, gentamicin and ciprofloxacin were found in methicillin-resistant isolates. These results should be taken into account for initiating empirical therapy of bacteremia when staphylococci are suspected.

Özet

Bu çalışmanın amacı, sistemik infeksiyon etkeni stafilokokların antibiyotiklere duyarlılığını saptamak idi. Kan kültürlerinden soyutlanan 45 Staphylococcus aureus ve 105 koagülaz-negatif stafilokok (KNS) kökeninin vankomisin, eritromisin, amikasin, gentamisin ve siprofloksasine in vitro duyarlılığı, disk difüzyon ve BIOMIC sistemi kullanılarak saptandı. Metisiline direnç oranları S. aureus ve KNS kökenlerinde sırasıyla, % 65 ve % 57 olarak bulundu. S. Aureus ve KNS kökenlerinin hiçbirinde vankomisin direnci saptanmazken, diğer antibiyotiklere değişen oranlarda direnç saptandı. Metisiline dirençli stafilokoklarda eritromisin, gentamisin ve siprofloksasine yüksek oranlarda direnç bulundu. Bu sonuçlar, stafilokoklann olası etken olabileceği bakteremilerin ampirik sağaltımında dikkate alınmalıdır.

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Cite This Article

ÜNLÜ, V. G., BAKICI, M. Z., ÜNLÜ, M., GÜR, D. (2022). Determination of the in vitro activity of several antimicrobial agents against blood culture isolates of Staphylococcus using the biomic system. İnfeksiyon Dergisi, Cilt: 15 - Sayı: 2, 235–238. https://ajindex.com/articles/546783

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