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Journals / İnfeksiyon Dergisi / 2001 / Cilt: 15 - Sayı: 4

Detection of clostridium difficile toxin A in antibiotic associated nosocomial diarrhea

Antibiyotikle ilişkili nozokomiyal diyarelerde clostridium difficile toksin A araştırılması

İmre ALTUĞLU
Altınay BİLGİÇ
Selda ERENSOY
Şöhret AYDEMİR
Ayşin ZEYTİNOĞLU
Pages
495–497
Publication Date
2022-10-17
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Toxin A was found in the stool specimens of seven (18.4%) patients.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Clostridium difficile has been recognized as the major cause of nosocomial diarrhea and pseudomembranous colitis in persons receiving antibiotic therapy.
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Key Findings & Data:Stool specimens of 38 patients hospitalized in intensive care units for more than three days receiving antibiotic therapy and then developed diarrhea were tested for Clostridium difficile toxin A with a commercial enzyme linked fluorescent assay (bio Merieux Vitek, France).
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Conclusion & Impact:Toxin A was found in the stool specimens of seven (18.4%) patients.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Clostridium difficile has been recognized as the major cause of nosocomial diarrhea and pseudomembranous colitis in persons receiving antibiotic therapy. The aim of the present study was to determine the prevalence of C. difficile in nosocomial diarrhea. Stool specimens of 38 patients hospitalized in intensive care units for more than three days receiving antibiotic therapy and then developed diarrhea were tested for Clostridium difficile toxin A with a commercial enzyme linked fluorescent assay (bio Merieux Vitek, France). Toxin A was found in the stool specimens of seven (18.4%) patients.

Özet

Clostridium difficile, antibiyotik ile ilişkili nozokomiyal diyare ve psödomembranöz kolit olgularından sorumlu olan bir bakteridir. Bu çalışmanın amacı, nozokomiyal diyarelerde C. difficile yerini belirlemek idi. Yoğun bakım ünitelerinde üç günden fazla yatarak antibiyotik kullanan ve diyare gelişen 38 hastaların dışkı örneklerinde "enzyme linked fluorescent assay" (bio Merieux Vitek, Fransa) ile C. difficile toksin A araştırıldı. Olguların yedisinin (%18.4) dışkı örneğinde C. difficile toksin A olumlu bulundu.

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Cite This Article

ALTUĞLU, İ., BİLGİÇ, A., ERENSOY, S., AYDEMİR, Ş., ZEYTİNOĞLU, A. (2022). Detection of clostridium difficile toxin A in antibiotic associated nosocomial diarrhea. İnfeksiyon Dergisi, Cilt: 15 - Sayı: 4, 495–497. https://ajindex.com/articles/546778

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