Journals / İnfeksiyon Dergisi / 2001 / Cilt: 15 - Sayı: 4

Comparison of serum endothelin-1 levels in chronic liver diseases and acute viral hepatitis

Kronik karaciğer hastalıkları ve akut viral hepatitte serum endotelin-1 düzeylerinin karşılaştırılması

Pages
429–432
Publication Date
2022-10-17
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The results indicated that the serum endothelin-1 levels of patients were significantly higher than those of healthy controls.

📌 3 Key Takeaways

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Objective & Hypothesis:The serum endothelin-1 levels in nine patients with chronic liver disease such as chronic active hepatitis, cirrhosis, cirrhosis plus hepatocellular carcinoma and in 16 cases of acute viral hepatitis were compared with those of 18 healthy controls.
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Key Findings & Data:The results indicated that the serum endothelin-1 levels of patients were significantly higher than those of healthy controls.
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Conclusion & Impact:In the chronic active hepatitis group that had the mildest histopathological liver changes endothelin-1 levels were significantly lower than those in other patient groups.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The serum endothelin-1 levels in nine patients with chronic liver disease such as chronic active hepatitis, cirrhosis, cirrhosis plus hepatocellular carcinoma and in 16 cases of acute viral hepatitis were compared with those of 18 healthy controls. The results indicated that the serum endothelin-1 levels of patients were significantly higher than those of healthy controls. In the chronic active hepatitis group that had the mildest histopathological liver changes endothelin-1 levels were significantly lower than those in other patient groups.

Özet

Bu çalışmanın amacı, kronik karaciğer hastalıkları ve akut viral hepatitte serum endotelin-1 düzeylerini değerlendirmek idi. Kronik aktif hepatit, siroz, siroz + hepatoselüler karsinom saptanan dokuz kronik karaciğer hastasının ve akut viral hepatitli 16 hastanın serum endotelin-1 düzeyleri sağlıklı kontrol ile karşılaştırıldı. Endotelin-1 düzeyleri enzim immünassay ile araştırıldı. Sonuç olarak, bu hasta gruplarında serum endotelin-1 düzeylerinin sağlıklı kontrol grubuna göre anlamlı derecede yüksek olduğu saptadı. Karaciğerdeki histopatolojik değişikliklerin diğerlerine göre daha hafif olduğu kronik aktif hepatitli hastalarda, diğer hasta gruplarına göre, serum endotelin-1 düzeylerinin anlamlı derecede düşük olduğu belirlendi.

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Cite This Article

İNAL, A., BEKTAŞ, A., DİZER, U., HAYAT, L., GÜNER, Ö., ŞENGÜL, A. (2022). Comparison of serum endothelin-1 levels in chronic liver diseases and acute viral hepatitis. İnfeksiyon Dergisi, Cilt: 15 - Sayı: 4, 429–432. https://ajindex.com/articles/546758

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