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Journals / İnfeksiyon Dergisi / 2001 / Cilt: 15 - Sayı: 3

Existence of chromosomal beta-lactamase and extended spectrum beta-lactamase in nonfermentative gram-negative bacteria

Nonfermentatif gram-negatif bakterilerde genişlemiş spektrumlu ve kromozomal beta-laktamaz varlığının araştırılması

A. Esin AKTAŞ
Doğruman Funda AL
Nimet YİĞİT
Ahmet AYYILDIZ
Altoparlak Ülkü ŞAHİN
Pages
315–318
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

ESBL activity was found to be positive in six (11.8%), and CBL in 33 (64.7%) of the strains.

📌 3 Key Takeaways

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Objective & Hypothesis:The purpose of the study was to determine the presence of chromosomal beta-lactamase and Extended Spectrum Beta-Lactamase (ESBL) in clinical isolates of nonfermentative gram-negative bacteria.
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Key Findings & Data:Totally 51 strains were studied: 22 Pseudomonas aeruginosa, 14 Pseudomonas flourescens, four Burkholderia cepacia, four Weeksella virosa, seven Acinetobacter baumannii.
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Conclusion & Impact:ESBL activity was found to be positive in six (11.8%), and CBL in 33 (64.7%) of the strains.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The purpose of the study was to determine the presence of chromosomal beta-lactamase and Extended Spectrum Beta-Lactamase (ESBL) in clinical isolates of nonfermentative gram-negative bacteria. Totally 51 strains were studied: 22 Pseudomonas aeruginosa, 14 Pseudomonas flourescens, four Burkholderia cepacia, four Weeksella virosa, seven Acinetobacter baumannii. Double disk synergy method for the detection of ESBL and direct induction method for the CBL activity were applied. Cefoxitine and imipenem were used as inducer agents. ESBL activity was found to be positive in six (11.8%), and CBL in 33 (64.7%) of the strains.

Özet

Klinik örneklerden izole edilen 22 Pseudomonas aeruginosa, 14 Pseudomonas fluorescens, dört Burkholderia cepacia, dört Weeksella virosa, yedi Acinetobacter baumannii olmak üzere toplam 51 non-fermentatif Gram-negatif bakteri suşunun genişlemiş spektrumlu beta-laktamaz (Extended Spectrum Beta Lactamase=ESBL) ve kromozomal beta-laktamaz oluşturmaları yönünden incelenmesi amaçlandı. ESBL üretiminin saptanması için çift disk sinerji testi, kromozomal beta-laktamazların saptanması için de direkt indüksiyon testi uygulandı. İndükleyici ajan olarak sefoksitin ve imipenem seçildi. Suşların altısının (%11.8) ESBL, 33'ünün (%64.7) kromozomal beta-laktamaz oluşturduğu saptandı.

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Cite This Article

AKTAŞ, A. E., AL, D. F., YİĞİT, N., AYYILDIZ, A., ŞAHİN, A. Ü. (2022). Existence of chromosomal beta-lactamase and extended spectrum beta-lactamase in nonfermentative gram-negative bacteria. İnfeksiyon Dergisi, Cilt: 15 - Sayı: 3, 315–318. https://ajindex.com/articles/546742

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