Cases of acute purulent meningitis: Risk factors involved in mortality

The study showed that despite development in antibiotic therapy, mortality is high in purulent meningitis and mortality is particulary high in patients admitted unconsciously, with meningitis caused by pneumococci and with low levels of glucose in cerebrospinal fluid.

📌 3 Key Takeaways

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Objective & Hypothesis:Acute purulent meningitis is associated with high mortality and morbidity.

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Key Findings & Data:In this study, between March 2001-December 2004 cases of acute purulent meningitis were evaluated and mortality risk factors were investigated.

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Conclusion & Impact:The study showed that despite development in antibiotic therapy, mortality is high in purulent meningitis and mortality is particulary high in patients admitted unconsciously, with meningitis caused by pneumococci and with low levels of glucose in cerebrospinal fluid.

🔬Design:Research Article

📍Scope:2001 Verileri

⚙️Variables:Domain Parameters

Abstract

Acute purulent meningitis is associated with high mortality and morbidity. In this study, between March 2001-December 2004 cases of acute purulent meningitis were evaluated and mortality risk factors were investigated. Acute purulent meningitis was diagnosed in 41 patients and 8 (19.5%) of them died. Etiological agents were detected in 17 (41.5 %) cases and most frequently (in 29.3 %) Streptococcus pneumoniae. Unconsciousness at admission, pneumococcal meningitis and low CSF glucose level were risk factors for mortality. The study showed that despite development in antibiotic therapy, mortality is high in purulent meningitis and mortality is particulary high in patients admitted unconsciously, with meningitis caused by pneumococci and with low levels of glucose in cerebrospinal fluid.

Özet

Akut pürülan meninjitlerde mortalite ve morbidite yüksektir. Bu çalışmada Mart 2001 -Aralık 2004 tarihleri arasında akut pürülan meninjit tanısı konulan hastalar incelenerek mortalite ile ilişkili risk faktörleri araştırılmıştır. Belirtilen tarihler arasında toplam 41 hastaya akut pürülan meninjit tanısı konulmuş ve bunların 8 (%19.5)'l mortal seyretmiştir. Hastaların 17'sinde (%41.5) etken saptanmış ve çoğunluğunda (%29.3) Streptococcus pneumoniae'nm etken olduğu bulunmuştur. İlk başvuran sırasında bilinç kapalılığı, pnömokoksik meninjit ve düşük beyin-omurilik sıvısı (BOS) glukoz düzeyi mortalite ile ilişkili risk faktörleri olarak bulunmuştur. Sonuç olarak, bu çalışmada antibiyotik tedavisindeki ilerlemelere rağmen akut pürülan meninjitlerde mortalitenin halen daha yüksek olduğu, bilinci kapalı olarak başvuran hastalarda, etkenin pnömokok olduğu olgularda ve BOS glukoz düzeyinin çok düşük olduğu durumlarda mortalite oranının arttığı gösterilmiştir.

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Cite This Article

BALABAN, N., BODUR, H., ÇEVİK, M. A., AKINCI, E., ÇOLPAN, A., BARAN, G., EREN, S. S., ERBAY, A. (2022). Cases of acute purulent meningitis: Risk factors involved in mortality. İnfeksiyon Dergisi, Cilt: 19 - Sayı: 3, 303–308. https://ajindex.com/articles/546521

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