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Journals / İnfeksiyon Dergisi / 2005 / Cilt: 19 - Sayı: 2

Blastoschizomyces capitatus infection with multiple organ involvement in a child with acute leucemia

Akut lösemili bir çocukta çoklu organ tutulumuna neden olan Blastoschizomyces capitatus infeksiyonu

Dilek Yeşim METİN
Hilmioğlu Süleyha POLAT
Ramazan İNCİ
Emel TÜMBAY
Tuba KARATAŞ
Erer Buket DEL-CASTELLO
Pages
257–262
Publication Date
2022-10-17
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The 7-year-old male patient with acute lymphocytic leukemia developed multiorgan infection due to the fungus during the period of bone marrow aplasia despite empiric antifungal therapy.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Blastoschizomyces capitatus, formerly known as Trichosporon capitatum and Geotrichum capitatum, is an opportunistic fungus that causes invasive infections in immunocompromised patients.
📊
Key Findings & Data:In this paper, a fatal case of B. capitatus infection is presented.
💡
Conclusion & Impact:The 7-year-old male patient with acute lymphocytic leukemia developed multiorgan infection due to the fungus during the period of bone marrow aplasia despite empiric antifungal therapy.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Blastoschizomyces capitatus, formerly known as Trichosporon capitatum and Geotrichum capitatum, is an opportunistic fungus that causes invasive infections in immunocompromised patients. In this paper, a fatal case of B. capitatus infection is presented. The 7-year-old male patient with acute lymphocytic leukemia developed multiorgan infection due to the fungus during the period of bone marrow aplasia despite empiric antifungal therapy.

Özet

Daha önce Trichosporon capitatum ve Geotrichum capitatum olarak bilinen Blastoschizomyces capitatus immün direnci baskılanmış hastalarda invazif infeksiyonlara neden olan fırsatçı bir mantardır. Yedi yaşında, akut lenfositer lösemili bir erkek çocukta, kemik iliği aplazisi döneminde gelişen ve empirik antifungal sağaltıma karşın çoklu organ tutulumu ile ölümcül seyreden B. capitatus infeksiyonu sunulmuştur.

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Cite This Article

METİN, D. Y., POLAT, H. S., İNCİ, R., TÜMBAY, E., KARATAŞ, T., DEL-CASTELLO, E. B. (2022). Blastoschizomyces capitatus infection with multiple organ involvement in a child with acute leucemia. İnfeksiyon Dergisi, Cilt: 19 - Sayı: 2, 257–262. https://ajindex.com/articles/546517

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References (15)

  1. Segal E, Elad D. Candida species and Blastoschizomyces capitatus. In: Collier L, Balows A, Susman M, eds. Topley and Wilson's Microbiology and Microbial infections. Vol 4. Ajello L, Hay RJ, vol eds. Medical Mycology. 9th ed. New York: Oxford University Press, 1998: 423-60
  2. Martino R, Subira M. Invasive fungal infections in hematology: new trends. Ann Hematol 2002; 81: 233-43
  3. Aşçıoglu S, Rex HJ, De Pauw B, et al. Defining opportunistic invasive fungal infctions in immunocompromised patients with cancer and hematopoietic stem cell transplants: an international consensus. Clin Infect Dis 2002; 34: 7-14
  4. Winston DJ, Balsley GE, Rhodes J, Linne SR. Disseminated Trichoporon capitatum infection in an immunosuppressed host. Arch Intern Med 1977; 137: 1192-5
  5. Salkin I, Gordon M, Samsonoff W, Rieder C. Blastoschizomyces capitatus, a new combination. Mycotaxon 1985; 22: 375-80
  6. Gueho E, De Hoog GS, Smith MT, Meyer SA. DNA relatedness, taxonomy, and medical significance of Geotrichum capitatum. J Clin Microbiol 1987; 25: 1191-4
  7. Haupt HM, Merz WG, Beschorner WE, Vaughan WP, Saral R. Colonization and infection with Trichosporon species in the immunosuppressed host. J Infect Dis 1983; 147: 199-203
  8. Martino P, Venditti M, Micozzi A, et al. Blastoschizomyces capitatus: An emerging cause of invasive fungal disease in leukemia patients. Rev Infect Dis 1990; 12: 570-82
  9. Arnold AG, Gribin B, Leval MDE, Macartney F, Slack M. Trichosporon capitatum causing recurrent fungal endocarditis. Thorax 1981; 36:478-80
  10. Ito T, Ishicawa Y, Fujii R, et al. Disseminated Trichosporon capitatum infection in a patient with acute leukemia. Cancer 1988; 61: 585-8
  11. Mahul P, Piens MA, Guyotat D, et al. Disseminated Geotrichum capitatum infection in a patient with acute myeloid leukemia. Mycoses 1989; 32: 573-7
  12. Polacheck I, Salkin IF, Kitzes-Cohen R, Raz R. Endocarditis caused by Blastoschizomyces capitatus and taxonomic review of the genus. J Clin Microbiol 1992; 30: 2318-22
  13. D' Antonio D, Piccolomini R, Fiortini G, et al. Osteomyelitis and intervertebral discitis caused by Blastoschizomyces capitatus in a patient with acute leukemia. J Clin Microbiol 1994; 32: 224-7
  14. Schiemann R, Glasmacher A, Bailly E, et al. Geotrichum capitatum septicaemia in neutropenic patients: case report and review of the literature. Mycoses 1998; 41:113-6
  15. Krcmery V Jr, Mateicka F, Kunova A, et al. Hematogenous trichosporonosis in cancer patients: report of 12 cases in