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Journals / İnfeksiyon Dergisi / 2005 / Cilt: 19 - Sayı: 4

E test investigation of antimicrobial susceptibilities of Stenotrophomonas maltophilia strains isolated from clinical specimens

Çeşitli klinik örneklereden izole edilen Stenotrophomonas maltophilia suşlarının antimikrobiyal duyarlılıklarının E test ile araştırılması

Alper KANDİŞER
Dilara ÖĞÜNÇ
Dilek ÇOLAK
Meral GÜLTEKİN
Gözde ÖNGÜT
Ayla ÖZCAN
Pages
425–428
Publication Date
2022-10-17
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The result of the study showed that the most effective antimicrobial agent against S. maltophilia strains isolated from clinical specimens was TMP/SMX.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Stenotrophomonas maltophilia which causes nosocomial infections is an opportunistic pathogen commonly found in the environment.
📊
Key Findings & Data:The aim of this study was to determine the antimicrobial susceptibilities of 36 clinical isolates of S. maltophilia collected from 31 patients in Akdeniz University Hospital Central Laboratory Microbiology Department, during August-October 2003 period.
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Conclusion & Impact:The result of the study showed that the most effective antimicrobial agent against S. maltophilia strains isolated from clinical specimens was TMP/SMX.
🔬Design:Research Article
📍Scope:2003 Verileri
⚙️Variables:Domain Parameters

Abstract

Stenotrophomonas maltophilia which causes nosocomial infections is an opportunistic pathogen commonly found in the environment. The bacterium is known to have intrinsic resistance to many antimicrobial agents due to its beta-lactamases, aminoglycozid acetyl-transferases, enzymes inactivating erythromycin and genes that code efflux pumps. During the antimicrobial chemotherapy, many problems arise due to this resistance. The aim of this study was to determine the antimicrobial susceptibilities of 36 clinical isolates of S. maltophilia collected from 31 patients in Akdeniz University Hospital Central Laboratory Microbiology Department, during August-October 2003 period. The strains were tested for susceptibility to trimethoprim-sulfamethoxazole (TMP/SMX), ticarcillin-clavulanate (TIM) and ciprofloxacin (C) with E-test. All of 36 S. maltophilia strains were susceptible to TMP/SMX, 24 of 36 (%66) were susceptible to TIM and 26 (%72) were susceptible to C. The result of the study showed that the most effective antimicrobial agent against S. maltophilia strains isolated from clinical specimens was TMP/SMX.

Özet

tenotrophomonas maltophilia doğada ve hastane ortamında yaygın olarak bulunan fırsatçı bir patojendir. Beta-laktamaz, aminoglikozit asetil transferaz ve eritromisini inaktive eden enzimleri ve eflüks pompaları kodlayan genleri nedeni ile S. maltophilia birçok antibiyotiğe intrensek olarak dirençlidir. Bu nedenle tedavide birçok direnç sorunuyla karşılaşılmaktadır. Çalışmada, Akdeniz Üniversitesi Hastanesi Merkez Laboratuvari Mikrobiyoloji Birimi'nde Ağustos-Kasım 2003 tarihleri arasında 31 hastaya ait 36 klinik örnekten izole edilen S. maltophilia suşlarının trimetoprim-sulfametoksazol (TMP/SXT), tikarsilin-klavulanat (TİM) ve siprofloksasin© duyarlılıklarının E-test yöntemiyle saptanması amaçlanmıştır. İncelenen 36 susun tümü TMP/SXT'e, 24 (%66)'ü TIM'a ve 26 (%72) 'sı siprofloksasine duyarlı olarak saptanmıştır. Sonuç olarak, S. maltophilia suşlarına in vitro en etkili antimikrobiyal ilacın TMP/SXT olduğu bulunmuştur.

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Cite This Article

KANDİŞER, A., ÖĞÜNÇ, D., ÇOLAK, D., GÜLTEKİN, M., ÖNGÜT, G., ÖZCAN, A. (2022). E test investigation of antimicrobial susceptibilities of Stenotrophomonas maltophilia strains isolated from clinical specimens. İnfeksiyon Dergisi, Cilt: 19 - Sayı: 4, 425–428. https://ajindex.com/articles/546470

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