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Journals / İnfeksiyon Dergisi / 2006 / Cilt: 20 - Sayı: 2

Investigation of siderophore and serum resistance in Klebsiella isolates

Klebsiella suşlarında siderofor ve serum direncinin araştırılması

Nural CEVAHİR
Umut YILDIRIM
Melek DEMİR
İlknur KALELİ
Pages
97–101
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Serum resistance was positive in 63.3% of the total strains.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The purpose of this study was to determine the production of siderophores and serum resistance in Klebsiella strains.
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Key Findings & Data:Of the total 120 strains 80 were obtained from urinary specimens and 40 from various other specimens.
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Conclusion & Impact:Serum resistance was positive in 63.3% of the total strains.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The purpose of this study was to determine the production of siderophores and serum resistance in Klebsiella strains. Of the total 120 strains 80 were obtained from urinary specimens and 40 from various other specimens. Of the 120 Klebsiella isolates, 90 were K. pneumoniae and 30 were K. oxytoca. Aerobactin and enterobactin production was determined by bioassay method. The production of aerobactin was found in 30.8% and enterobactin in 91.7% of the isolates. Serum resistance was positive in 63.3% of the total strains.

Özet

Bu çalışmanın amacı, Klebsiella kökenlerinde siderofor ve serum direncini saptamak idi. Çalışmaya alınan toplam 120 Klebsiella kökeninin 80'ni idrar örneklerinden, 40'ı diğer örneklerden soyutlanmıştı.Toplam 120 suşun 90'ı K. pneumoniae, 30'u K. oxytoca idi. Aerobaktin ve enterobaktin varlığı biyolojik yöntemle araştırıldı. Toplam 120 Klebsiella suşunun %30.8'inin aerobaktin, %91.7'sinin enterobaktin sentezlediği bulundu. Enterobaktin sentezi aerobaktin sentezinden daha yüksek bulundu. Suşların %63.3'ünde serum direnci pozitif olarak saptandı.

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Cite This Article

CEVAHİR, N., YILDIRIM, U., DEMİR, M., KALELİ, İ. (2022). Investigation of siderophore and serum resistance in Klebsiella isolates. İnfeksiyon Dergisi, Cilt: 20 - Sayı: 2, 97–101. https://ajindex.com/articles/546458

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References (16)

  1. Koneman EW, Allen SD, Janda WM, Schreckenberger PC, Winn WC. Color Atlas and Textbook of Diagnostic Microbiology. 5th ed. Philadelphia: JB Lippincott Co, 1997: 171-252
  2. Erdem B. Enterobacteriaceae. Ustaçelebi Ş, ed. Temel ve Klinik Mikrobiyoloji'öe. Ankara: Güneş Kitabevi, 1999: 471-517
  3. Podschun R, Ullman U. Klebsiella spp. as nosocomial pathogens: Epidemiology, taxonomy, typing methods and pathogenity factors. Clin Microbiol Rev 1998; 11: 589-603
  4. Neilands JB. Siderophores: Structure and function of microbial iron transport compounds. J Biol Chem 1995; 270: 26723-6
  5. Wooldridge KG, Williams PH. Iron uptake mechanism of pathogenic bacteria. FEMS Microbiol Rev 1993; 12: 325-48
  6. Erdem B. Bakterilerde sideroforlar ve diğer demir alım sistemleri. Infek Derg 1996; 10: 101-3
  7. Neilands JB. Siderophores. Arch Biochem Biophys 1993; 302: 1-3
  8. Rabsch W, Reissbrodt R. Biotest zum Nachweis von hydroxamat-Fe-chelatoren (Aerobactin). J Basic Microbiol 1985; 25: 663-7
  9. Rabsch W, Reissbrodt R. Investigations of Salmonella strains from different clinical-epidemiological orgin with phenolate and hydroxamate (aero- bactin) siderophore bioassays. J Hyg Epidemiol Microbiol Immunol 1988; 32: 353-60
  10. Puzova H, Siegfried L, Kmetova M, Filka J, Takacova V, Durovicova J. Fimbriation, surface hydrophobicity and serum resistance in uropathogenic strains of Escherichia coli. FEMS Immunol Med Microbiol 1994; 9: 223-9
  11. Podschun R, Fischer A, Ullmann U. Siderophore production of Klebsiella species isolated from different sources. Zentralbl Bakteriol 1992; 276: 481-6
  12. Anğ Küçüker M, Küçükbasmacı B, Tekin M, Akbulut D, Büyükbaba-Boral Ö, Anğ Ö. Üropatojen Klebsiella suşlarının serotiplendirilmesi, siderofor sentezi, serum direnci ve genişlemiş spektrum betalaktamaz tayini. Türk Mikrobiol Cem Derg 2002; 32: 265-9
  13. Jaya B, Sanjay C. Siderophore production by clinical isolates of Klebsiella pneumoniae. Ind J Med Microbiol 1995; 13: 34-6
  14. Tarkkanen AM, Allen BL, Williams PH, et al. Fimbriation, capsulation, and iron-scavenging systems of Klebsiella strains associated with human urinary tract infection. Infect Immun 1992; 60:1187-92
  15. Podschun R, Pietsch S, Holler C, Ullmann U. Incidence of Klebsiella species in surface waters and their expression of virulence factors. Appl Env Microbiol 2001; 67: 3325-7
  16. Anğ Küçüker M, Topal A, Törümküney D ve ark. Prematüre yenidoğanlardan alınan klinik örneklerden izole edilen Klebsiella pneumoniae suşları