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Journals / İnfeksiyon Dergisi / 2006 / Cilt: 20 - Sayı: 1

Comparison of a quantiFERON-TB test with tuberculin skin test in patients of latent and active tuberculosis infection

Latent ve aktif tüberkülozu olan hastalarda tüberkülin deri testi ile quantiFERON-TB testinin karşılaştırılması

Altınay BİLGİÇ
Candan ÇİÇEK
F. Engin YAYGIN
Gürsel ÇOK
Mustafa ÖZHAN
Pages
15–18
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Group II consisted of 20 patients who were TST positive (TST>15mm) and Group III consisted of 12 patients who were TST negative (TST

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Tuberculin skin test has been used for many years for the diagnosis of latent tuberculosis infection.
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Key Findings & Data:A total of 53 patients were evaluated in this study.
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Conclusion & Impact:Group II consisted of 20 patients who were TST positive (TST>15mm) and Group III consisted of 12 patients who were TST negative (TST
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Tuberculin skin test has been used for many years for the diagnosis of latent tuberculosis infection. The aim of this study was to compare the effectiveness of tuberculin skin test (TST) and QuantiFERON-TB (QFT) in diagnosing latent and active tuberculosis. A total of 53 patients were evaluated in this study. Group I consisted of 21 patients with primary active tuberculosis. Group II consisted of 20 patients who were TST positive (TST>15mm) and Group III consisted of 12 patients who were TST negative (TST

Özet

Tüberkülin deri testi, latent tüberküloz infeksiyonun tanısında yıllardır kullanılmaktadır. Bu çalışmada, aktif ve latent tüberkülozlu kişilerde tüberkülin deri testi ile QuantiFERON-TB testinin etkinliğini araştırmak amaçlanmıştır. Elli üç kişi değerlendirmeye alınmıştır. Grup I, primer aktif tüberkülozlu 21 hastadan oluşmaktadır. Grup II tüberkülin deri testi pozitif olan (TDT>15 mm) 20 kişiden ve Grup III ise tüberkülin deri testi negatif (TDT< 5 mm) olan 11 kişiden oluşmaktadır. Hastaların tümüne tüberkülin deri testi ve QuantiFERON-TB testi uygulanmıştır. Grup I'de QuantiFERON-TB testi ile yedi hasta pozitif, iki hasta negatif olarak bulunmuş ve 12 hastada mitojen uyarımı izlenmemiştir. QuantiFERON-TB testi Grup II'deki hastaların biri hariç tümünde pozitif, Grup III'deki hastaların biri hariç tümünde de negatif bulunmuştur. QuantiFERON-TB testinin aktif tüberkülozlu hastaların çoğunluğunda mitojen uyarımı olmaması nedeniyle başarısız olduğu izlenmiştir. Ancak latent tüberkülozu olan ve tüberkülin deri testi negatif olan kişilerde QuantiFERON-TB testi sonuçları TDT ile eşdeğer bulunmuştur.

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Cite This Article

BİLGİÇ, A., ÇİÇEK, C., YAYGIN, F. E., ÇOK, G., ÖZHAN, M. (2022). Comparison of a quantiFERON-TB test with tuberculin skin test in patients of latent and active tuberculosis infection. İnfeksiyon Dergisi, Cilt: 20 - Sayı: 1, 15–18. https://ajindex.com/articles/546446

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