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Journals / İnfeksiyon Dergisi / 2006 / Cilt: 20 - Sayı: 2

Two new protein synthesis inhibitors: Linezolid and streptogramins (Quinupristin/dalfoprustin)

İki yeni protein sentez inhibitörü: Linezolit ve streptograminler (Kinopristin/dalfoprustin)

Davut ÖZDEMİR
Abdülkadir KÜÇÜKBAYRAK
Pages
145–151
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Due to the unique action mechanism of oxazolidinones, it is believed that oxazolidinones do not show cross resistance with other types of antibiotics.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Since 1999 the streptogramin combination quinupristin/dalfoprustin and the oxazolidinone linezolid, new classes of synthetic antibacterial agents, exhibit activity against a large number of Gram-positive organisms.
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Key Findings & Data:Their mode of action has been shown to inhibit protein synthesis.
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Conclusion & Impact:Due to the unique action mechanism of oxazolidinones, it is believed that oxazolidinones do not show cross resistance with other types of antibiotics.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Since 1999 the streptogramin combination quinupristin/dalfoprustin and the oxazolidinone linezolid, new classes of synthetic antibacterial agents, exhibit activity against a large number of Gram-positive organisms. Their mode of action has been shown to inhibit protein synthesis. Due to the unique action mechanism of oxazolidinones, it is believed that oxazolidinones do not show cross resistance with other types of antibiotics.

Özet

Streptogramin grubundan olan kinopristin/dalfoprustin kombinasyonu ve oksazolidinon grubundan olan linezolit Gram-pozitif infeksiyonlara neden olan patojenlere karşı etki gösteren ve 1999'dan beri kullanımda olan iki yeni kuşak antibiyotiktir. Her ikisi de protein sentezi inhibisyonu yaparak etki gösterirler. Oksazolidinonlar farklı etki mekanizmaları nedeniyle diğer antibiyotikler ile çapraz direnç göstermezler.

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Cite This Article

ÖZDEMİR, D., KÜÇÜKBAYRAK, A. (2022). Two new protein synthesis inhibitors: Linezolid and streptogramins (Quinupristin/dalfoprustin). İnfeksiyon Dergisi, Cilt: 20 - Sayı: 2, 145–151. https://ajindex.com/articles/546418

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