AI Summary & Key Takeaways
AI InsightDoxa-zosin treatment was associated with significant improvement in HDL and apo B (p
📌 3 Key Takeaways
Abstract
Antihypertensive, Cardiac and Metabolic Effects of Doxazosin in Essential Hypertension In this study, we aimed to evaluate the effect of doxazosin theraphy (1-4 mg/day) on blood pressure, left ventricular mass, systolic and diastolic functions and metabolic profile in patients with mild or moderate essential hypertension.Thirty-four patients, who were included in the study, were serially studied during 12 weeks with 2 weekly intervals by recording of blood pressures, heart rate, metabolic profile and echo-cardiogram. After 3-month treatment systolic blood pressure and diastolic blood pressure were significantly reduced (p0.05). Doxa-zosin treatment was associated with significant improvement in HDL and apo B (p
Özet
Bu çalışmamızda, selektifpostsinaptikCLl-adrenoreseptör blokeri olan doksazosinin hafif ve¬ya orta dereceli esansiyel hipertansiyonlu olguların tedavisindeki yeri ile kardiyak ve metabolik etkilerini araştırmayı amaçladık. Çalışmaya 20'si (%58.8) kadın, 14'ü (%41.1) erkek ve yaş ortalaması 53 ±8.2 yıl olan hafif veya orta dereceli esansiyel hipertansiyonulu 34 olgu alındı. Oniki haftalık doksazosin tedavisi sonrasında hem diastolik kan basıncında (p