Protective effect of Melatonin and Ganoderma lucidum against the negative effects of extremely low frequency electric and magnetic fields in the periodontal tissues
A statisticallysignificant difference was determined in the groups treated with MLT andGL (p
📌 3 Key Takeaways
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Objective & Hypothesis:Aim: The purpose of this study was to determine whether extremely lowfrequency electric and magnetic field (ELF-EMF) had any detrimentaleffects on periodontal tissue and to investigate, histologically andimmunohistochemically whether melatonin (MLT) and Ganodermalucidum (GL) had a protective role against these detrimental effects.Methodology: A total of 56 adults, male Wistar Albino rats were usedin this study.
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Key Findings & Data:Rats were divided into 7 equal groups and exposed to ELFEMF,which was produced by a high voltage source, 8 hours / day for 26days.
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Conclusion & Impact:A statisticallysignificant difference was determined in the groups treated with MLT andGL (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters
Abstract
Aim: The purpose of this study was to determine whether extremely lowfrequency electric and magnetic field (ELF-EMF) had any detrimentaleffects on periodontal tissue and to investigate, histologically andimmunohistochemically whether melatonin (MLT) and Ganodermalucidum (GL) had a protective role against these detrimental effects.Methodology: A total of 56 adults, male Wistar Albino rats were usedin this study. Rats were divided into 7 equal groups and exposed to ELFEMF,which was produced by a high voltage source, 8 hours / day for 26days. GL (20 mg / kg / day) and MLT (10 mg / kg / day) were administeredby the oral gavage and intraperitoneal method.Results: Fibrous degeneration in the periodontal membrane,inflammatory cell infiltration, connective tissue fiber organization,dilation, and hemorrhage in the blood vessels changes were determinedin the periodontal tissue of the rats in groups I and IV. A statisticallysignificant difference was determined in the groups treated with MLT andGL (p
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Cite This Article
YAVAŞ, M. C., GÜL, M., DÜNDAR, S. (2022). Protective effect of Melatonin and Ganoderma lucidum against the negative effects of extremely low frequency electric and magnetic fields in the periodontal tissues. International Dental Research, Cilt: 9 - Sayı: 3, 119–126. https://ajindex.com/articles/539522
Hashish AH, El-Missiry MA, Abdelkader HI, Abou-Saleh RH. Assessment of biological changes of continuous whole body exposure to static magnetic field and extremely low frequency electromagnetic fields in mice. Ecotoxicol Environ Saf. 2008;71(3):895-902. (Crossref
McCann J, Dietrich F, Rafferty C. The genotoxic potential of electric and magnetic fields: an update. Mutat Res. 1998;411(1):45-86. (Crossref
Ivancsits S, Diem E, Jahn O, Rüdiger HW. Intermittent extremely low frequency electromagnetic fields cause DNA damage in a dose-dependent way. Int Arch Occup Environ Health. 2003;76(6):431-6. (Crossref
Oksay T, Naziroğlu M, Doğan S, Güzel A, Gümral N, Koşar PA. Protective effects of melatonin against oxidative injury in rat testis induced by wireless (2.45 GHz) devices. Andrologia. 2014;46(1):65-72. (Crossref
Feychting M, Jonsson F, Pedersen NL, Ahlbom A. Occupational magnetic field exposure and neurodegenerative disease. Epidemiology. 2003;14(4):413-419; discussion 427-8. (Crossref
Franzellitti S, Valbonesi P, Ciancaglini N, Biondi C, Contin A, Bersani F, et al. Transient DNA damage induced by highfrequency electromagnetic fields (GSM 1.8 GHz) in the human trophoblast HTR-8/SVneo cell line evaluated with the alkaline comet assay. Mutat Res. 20105;683(1-2):35-42. (Crossref
Yokus B, Akdag MZ, Dasdag S, Cakir DU, Kizil M.Extremely low frequency magnetic fields cause oxidative DNA damage in rats. Int J Radiat Biol. 2008;84(10):789-95. (Crossref
Yokus B, Cakir DU, Akdag MZ, Sert C, Mete N. Oxidative DNA damage in rats exposed to extremely low frequency electro magnetic fields. Free Radic Res. 2005 Mar;39(3):317-23. (Crossref
Zmyslony M. Weak (5 mT) static magnetic field stimulates lipid peroxidation in isolated rat liver microsomes in vitro. Electro and Magnetobiology. 1998;17(2):109-113. (Crossref
Akdag MZ, Dasdag S, Canturk F, Karabulut D, Caner Y, Adalier N. Does prolonged radiofrequency radiation emitted from Wi- Fi devices induce DNA damage in various tissues of rats? J Chem Neuroanat. 2016;75(Pt B):116-22. (Crossref
Kimura S, Yonemura T, Kaya H. Increased oxidative product formation by peripheral blood polymorphonuclear leukocytes in human periodontal diseases. J Periodontal Res. 1993;28(3):197-203. (Crossref
Zamanian A, Hardiman C. Electromagnetic Radiation and Human Health: A Review of Sources and Effects. High Frequency Electronics. 2005;4(3):16-26
Doğan MS, Yavaş MC, Günay A, Yavuz İ, Deveci E, Akku