Journals / Infectious diseases and clinical microbiology (Online) / 2021 / Cilt: 3 - Sayı: 1

Persistent Symptoms After Discharge ofCOVID-19 patients

Pages
22–30
Publication Date
2022-10-19
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

The discharged patients were surveyed for their symptoms by calling.Results: On average, 14 weeks after being discharged, it was found that a least one symptom persisted in 27.4% (n =73) of 266 patients.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Many observational studies have reported high morbidity and mortality associated with COVID-19 during hospitalisation.
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Key Findings & Data:This study aimed to examine the longterm symptoms and related factors of patients hospitalised due to COVID-19.Materials and Methods: Clinical and laboratory characteristics of 266 patients who were followed up in the hospital with the diagnosis of COVID-19 were recorded.
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Conclusion & Impact:The discharged patients were surveyed for their symptoms by calling.Results: On average, 14 weeks after being discharged, it was found that a least one symptom persisted in 27.4% (n =73) of 266 patients.
🔬Design:Survey & Empirical Study
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Many observational studies have reported high morbidity and mortality associated with COVID-19 during hospitalisation. This study aimed to examine the longterm symptoms and related factors of patients hospitalised due to COVID-19.Materials and Methods: Clinical and laboratory characteristics of 266 patients who were followed up in the hospital with the diagnosis of COVID-19 were recorded. The patients were followed for an average of 14 weeks after discharge. The discharged patients were surveyed for their symptoms by calling.Results: On average, 14 weeks after being discharged, it was found that a least one symptom persisted in 27.4% (n =73) of 266 patients. The three most common symptoms after discharge were 38.3% (n = 28) cough, headache (36.9%, n = 27), shortness of breath (27.3%, n = 20), respectively. In multivariate analysis, it was found that symptoms persist more in patients with high CRP (C-reactive protein) and ferritin during hospitalisation (p: 0.03; p: 0.005, respectively). Conclusion: After COVID-19, it was observed that complaints continued after discharge in a significant number of patients. During hospitalisation, high ferritin and CRP levels were found to be associated with the persistence of symptoms. It was considered that symptoms associated with COVID-19 persist more in those with a high inflammatory response.

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Cite This Article

EVLİCE, O., KUŞ, F., BEKTAŞ, M. (2022). Persistent Symptoms After Discharge ofCOVID-19 patients. Infectious diseases and clinical microbiology (Online), Cilt: 3 - Sayı: 1, 22–30. https://ajindex.com/articles/539090

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References (10)

  1. 1 World HealthCenters for Disease Control and Prevention (CDC). Long-Term Effects of COVID-19. 2020 Nov 13 (cited 2021 January 11). Available from: https://www.cdc.gov/coronavirus/2019-ncov/ long-term-effects.html. 2 National Institute for Health and Care Excellence (NICE). COVID-19 rapid guideline: managing the long-term effects of COVID-19. 2020 Dec 18 (cited 2021 January 11). Available from: https://www.nice.org.uk/guidance/NG188. 3 Goërtz YMJ, Van Herck M, Delbressine JM, Vaes AW, Meys R, Machado FVC, et al. Persistent symptoms 3 months after a SARS-CoV-2 infection: the post-COVID-19 syndrome? ERJ Open Res 2020
  2. 00542-2020. 4 World Health Organization. Global surveillance for COVID-19 caused by human infection with COVID-19 virus: interim guidance. 2020 March 20 (cited 2021 January 11). Available from: https://apps.who.int/iris/handle/10665/331506. 2020. 5 Magnus P, Gunnes N, Tveito K, Bakken IJ, Ghaderi S, Stoltenberg C, et al. Chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ ME) is associated with pandemic influenza infection, but not with an adjuvanted pandemic influenza vaccine. Vaccine 2015
  3. 6 Moldofsky H, Patcai J. Chronic widespread musculoskeletal pain, fatigue, depression and disordered sleep in chronic post-SARS syndrome
  4. a case-controlled study. BMC Neurol. 2011
  5. 7 Huang C, Huang L, Wang Y, Li X, Ren L, Gu X, et al. 6-month consequences of COVID-19 in patients discharged from hospital: a cohort study. Lancet 2021
  6. 8 Galal I, Hussein AARM, Amin MT, Saad MM, Zayan HEE, Abdelsayed MZ, et al. Determinants of persistent post COVID-19 symptoms: value of a novel COVID-19 symptoms score. Medrxiv 2020. 11.11.20230052 9 Kernan KF, Carcillo JA. Hyperferritinemia and inflammation. Int Immunol 2017
  7. 401–9. 10 Rosário C, Zandman-Goddard G, Meyron-Holtz EG, D'Cruz DP, Shoenfeld Y. The hyperferritinemic syndrome: macrophage activation syndrome, Still's disease, septic shock and catastrophic antiphospholipid syndrome. BMC Med. 2013
  8. 11 Lalueza A, Ayuso B, Arrieta E, Trujillo H, Folgueira D, Cueto C, et al. Elevation of serum ferritin levels for predicting a poor outcome in hospitalized patients with influenza infection. Clin Microbiol Infect 2020
  9. e9-1557.e15 12 Huang I, Pranata R, Lim MA, Oehadian A, Alisjahbana B. C-reactive protein, procalcitonin, D-dimer, and ferritin in severe coronavirus disease-2019: a meta-analysis. Ther Adv Respir Dis 2020
  10. 1753466620937175. 13 Sun X, Wang T