Journals / Haseki Tıp Bülteni / 2020 / Cilt: 58 - Sayı: 3

Factors Affecting Outcomes of Salvage Micro Testicular Sperm Extraction Following a Failed Testicular Sperm Extraction

Başarısız Testiküler Sperm Ekstraksiyonu Sonrası Yapılan Kurtarma Mikro Testicular Sperm Extraction Sonuçlarını Etkileyen Unsurlar

Pages
281–285
Publication Date
2022-10-17
DOI
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The rate of patients with SCOS was significantly higher in the failure group (p

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Objective & Hypothesis:Aim: To investigate the likelihood of sperm retrieval in repeated micro-testicular sperm extraction (micro-TESE) in non-obstructive azoospermia (NOA) patients.Methods: Data of 310 patients, who underwent a micro-TESE procedure at a center experienced in in vitro fertilization between January 2015 and July 2019, was evaluated retrospectively.
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Key Findings & Data:Seventy-three patients who had a previous failed sperm retrieval procedure (33 micro-TESE, and 40 TESE) were included in the study.
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Conclusion & Impact:The rate of patients with SCOS was significantly higher in the failure group (p
🔬Design:Research Article
📍Scope:2015 Verileri
⚙️Variables:Domain Parameters

Abstract

Aim: To investigate the likelihood of sperm retrieval in repeated micro-testicular sperm extraction (micro-TESE) in non-obstructive azoospermia (NOA) patients.Methods: Data of 310 patients, who underwent a micro-TESE procedure at a center experienced in in vitro fertilization between January 2015 and July 2019, was evaluated retrospectively. Seventy-three patients who had a previous failed sperm retrieval procedure (33 micro-TESE, and 40 TESE) were included in the study. The patients were divided into two groups (group 1: successful, group 2: failure) according to sperm retrieval in salvage micro-TESE. The groups were compared in terms of demographic characteristics and hormonal and histological features.Results: The mean age of the patients was 36.71±8.1 (25-45) years and duration of infertility was 59.45±21.4 (22-247) months. The sperm retrieval rate in patients who underwent salvage micro-TESE was 36.99% (27/73). Sperm retrieval rates were 8/43, 8/16 and 11/14 for patients diagnosed with Sertoli Cell-only syndrome (SCOS), maturation arrest and hypospermatogenesis. The rate of patients with SCOS was significantly higher in the failure group (p

Özet

Amaç: Daha önce başarısız testiküler sperm ekstraksiyonu (TESE) öyküsüne sahip non-obstrüktif azospermi (NOA) hastalarında kurtarma mikro-TESE işleminin sperm bulma olasılığını etkileyen faktörleri analiz etmektir. Yöntemler: Ocak 2015 ve Temmuz 2019 tarihleri arasında in vitro fertilizasyon konusunda deneyimli bir merkezde TESE uygalanan 310 hastanın verileri incelendi. Daha önce başarısız mikro-TESE öyküsü olan 73 hasta (33 mikro-TESE, 40 TESE) çalışmaya dahil edildi. Kurtarma mikro-TESE işleminde sperm bulunan hastalar “başarılı”; bulunamayanlar ise “başarısız” olarak sınıflandırıldı. Gruplar demografik veriler, hormonal durum ve histolojik bulgular açısından karşılaştırıldı. Bulgular: Hastaların ortalama yaşı ve infertilite süresi sırasıyla 36,71±8,1 (25-45) yıl ve 59,45±21,4 (22-247) ay idi. Kurtarma mikro-TESE sonrasında sperm elde etme oranı %36,99 (27/73) idi. Sperm elde etme oranları Sertoli Cell-only Syndrome (SCOS), maturasyon arresti and hipospermatogenesis için sırasyla 8/43, 8/16 ve 11/14 idi. Gruplar arasında yaş, infertilite süresi, kurtarma mikro TESE öncesi hormon parametreleri açısından anlamlı farklılık izlenmedi. Başarısız grupta anlamlı olarak SCOS oranı daha yüksek idi (p

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Cite This Article

ÇUBUK, A., BALABAN, M., ÖZKAPTAN, O. (2022). Factors Affecting Outcomes of Salvage Micro Testicular Sperm Extraction Following a Failed Testicular Sperm Extraction. Haseki Tıp Bülteni, Cilt: 58 - Sayı: 3, 281–285. https://ajindex.com/articles/535030

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