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Journals / Haseki Tıp Bülteni / 2022 / Cilt: 60 - Sayı: 1

A Comparative Study of the Effectiveness of Serum C-reactive Protein and Serum Pentraxin-3 Levels in the Diagnosis and Follow-up of Neonatal Sepsis

Kamil ŞAHİN
Hatice Nilgun DURU
Murat ELEVLİ
Demet OĞUZ
Emel ATAOĞLU
Tugrul ATAY
Ala ÜSTYOL
Pages
33–39
Publication Date
2022-10-17
DOI
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⚡ TL;DR(Too Long; Didn't Read)

A significant correlation was observed between pentraxin 3 levels and serum C-reactive protein levels (r=0.44, p

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: Neonatal sepsis is a disease with multisystemic involvement accompanied by bacteremia in the first 28 days of life and in which the pathogen micro-organism spreads to different systems via the blood.
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Key Findings & Data:The purpose of this study was to investigate the effectiveness of pentraxin 3 in neonatal sepsis.
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Conclusion & Impact:A significant correlation was observed between pentraxin 3 levels and serum C-reactive protein levels (r=0.44, p
🔬Design:Research Article
📍Scope:2015 Verileri
⚙️Variables:Domain Parameters

Abstract

Aim: Neonatal sepsis is a disease with multisystemic involvement accompanied by bacteremia in the first 28 days of life and in which the pathogen micro-organism spreads to different systems via the blood. Laboratory tests with high sensitivity and specificity are needed for the early diagnosis of neonatal sepsis. The purpose of this study was to investigate the effectiveness of pentraxin 3 in neonatal sepsis. Methods: This prospective clinical study was performed between November, 2015, and March, 2016, with 49 newborns diagnosed with sepsis and under monitoring at the neonatal intensive care unit and with Tollner sepsis scores of 5 or above and with 35 healthy neonates. Blood was collected from every patient diagnosed with sepsis for complete blood count, C-reactive protein, blood culture and pentraxin 3 measurements. Results: No significant difference was determined between the patient and control groups in terms of birth weight or gender. C-reactive protein, leukocyte, and pentraxin 3 levels were found to differ significantly between the healthy newborns in the control group and the septic patients. A significant correlation was observed between pentraxin 3 levels and serum C-reactive protein levels (r=0.44, p

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Cite This Article

ŞAHİN, K., DURU, H. N., ELEVLİ, M., OĞUZ, D., ATAOĞLU, E., ATAY, T., ÜSTYOL, A. (2022). A Comparative Study of the Effectiveness of Serum C-reactive Protein and Serum Pentraxin-3 Levels in the Diagnosis and Follow-up of Neonatal Sepsis. Haseki Tıp Bülteni, Cilt: 60 - Sayı: 1, 33–39. https://ajindex.com/articles/534957

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