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Journals / Güncel Pediatri / 2008 / Cilt: 6 - Sayı: 2

The relationship between serum insulin-like growth factor-1 levels and retinopathy of prematurity

Prematüre retinopatisi ile serum insülin benzeri büyüme faktörü-1 düzeyleri arasındaki ilişki

Merih ÇETİNKAYA
Ahmet T. ÖZMEN
Nigün KÖKSAL
Hilal ÖZKAN
Pages
47–52
Publication Date
2022-10-18
DOI
—
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Aim: The aim of this study was to investigate the association between serum insulin like growth factor I (IGF-I) and retinopathy of prematurity (ROP).Materials and Method: We prospectively studied the newborn infants born at a postmenstrual age of

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Objective & Hypothesis:Aim: The aim of this study was to investigate the association between serum insulin like growth factor I (IGF-I) and retinopathy of prematurity (ROP).Materials and Method: We prospectively studied the newborn infants born at a postmenstrual age of
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Key Findings & Data:Aim: The aim of this study was to investigate the association between serum insulin like growth factor I (IGF-I) and retinopathy of prematurity (ROP).Materials and Method: We prospectively studied the newborn infants born at a postmenstrual age of
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Conclusion & Impact:Aim: The aim of this study was to investigate the association between serum insulin like growth factor I (IGF-I) and retinopathy of prematurity (ROP).Materials and Method: We prospectively studied the newborn infants born at a postmenstrual age of
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📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: The aim of this study was to investigate the association between serum insulin like growth factor I (IGF-I) and retinopathy of prematurity (ROP).Materials and Method: We prospectively studied the newborn infants born at a postmenstrual age of

Özet

Amaç: Bu çalışmanın amacı serum insülin benzeri büyüme faktörü-I (IGF-I) ile prematüre retinopatisi (ROP) arasında ilişki olup olmadığının belirlenmesidir.Gereç ve Yöntem: Bu prospektif çalışmaya Kasım 2006 ile Mayıs 2007 arasında 34 gestasyonel haftadan küçük olarak doğan toplam 33 bebek dahil edildi. Prematüre retinopatisi (ROP), uluslararası ROP sınıflandırmasına göre sınıflandırıldı. Serum IGF-I düzeyleri doğumdan hemen sonra çalışılmaya başlandı ve olgular taburcu edilene kadar haftalık olarak çalışılmaya devam edildi.Bulgular: Çalışmaya alınan 33 bebekten %36’sında ROP saptandı. Düşük doğum ağırlığı ve daha küçük gestasyonel yaş daha yüksek ROP gelişimi oranı ile ilişkili idi. ROP grubundaki ortalama serum IGF-1 düzeylerinin ROP olmayan gruba göre istatistiksel olarak anlamlı düşük olduğu bulundu (p=0,03). Haftalık ölçülen serum IGF-1 düzeyleri ile ROP gelişimi arasında ise istatistiksel olarak anlamlı ilişki saptanmadı (p>0,05).Tartışma: Sonuç olarak, preterm bebeklerdeki düşük ortalama IGF-1 düzeyleri ROP gelişimi oranı ile ilişkili bulunmuştur.

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Cite This Article

ÇETİNKAYA, M., ÖZMEN, A. T., KÖKSAL, N., ÖZKAN, H. (2022). The relationship between serum insulin-like growth factor-1 levels and retinopathy of prematurity. Güncel Pediatri, Cilt: 6 - Sayı: 2, 47–52. https://ajindex.com/articles/528112

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