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Journals / Güncel Pediatri / 2009 / Cilt: 7 - Sayı: 1

Hypothyroidism and muscle pseudohypertrophy: Kocher-debre semelaigne syndrome

Hipotiroidi ve kas psödohipertrofisi: Kocher-debre semelaigne sendromu

Tolga Altuğ ŞEN
Tevfik DEMİR
Reşit KÖKEN
Hamide MELEK
Özlem GÜRAKSIN
Hafza UÇAR
Gülay GÜN
Faruk ALPAY
Pages
37–40
Publication Date
2022-10-18
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this article, we emphasized hypothyroid myopathy by reporting a-13 4/12-year old girl with short stature who was diagnosed with hypothyroidism due to thyroid aplasia that caused pseudohypertrophy of muscles.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Long standing hypothyroidism without therapy leads to myopathy which is associated with proximal muscle weakness, fatigue, exertional pain, pseudohypertrophy due to myoedema, diminished deep tendon reflexes, and stiffness in muscles.
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Key Findings & Data:Kocher-Debre-Semelaigne syndrome is a specific, rare form of hypothyroid myopathy, which causes hypertrophy of muscles.
💡
Conclusion & Impact:In this article, we emphasized hypothyroid myopathy by reporting a-13 4/12-year old girl with short stature who was diagnosed with hypothyroidism due to thyroid aplasia that caused pseudohypertrophy of muscles.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Long standing hypothyroidism without therapy leads to myopathy which is associated with proximal muscle weakness, fatigue, exertional pain, pseudohypertrophy due to myoedema, diminished deep tendon reflexes, and stiffness in muscles. Kocher-Debre-Semelaigne syndrome is a specific, rare form of hypothyroid myopathy, which causes hypertrophy of muscles. In this article, we emphasized hypothyroid myopathy by reporting a-13 4/12-year old girl with short stature who was diagnosed with hypothyroidism due to thyroid aplasia that caused pseudohypertrophy of muscles.

Özet

Uzun süre tedavi edilmeyen hipotiroidi nedeniyle gelişen miyopatili olgularda proksimal kas güçsüzlüğü, egzersizle ortaya çıkan kas ağrıları, kas ödemine bağlı psödohipertrofi, derin tendon reflekslerinde azalma, kaslarda sertleşme vardır. Hipotiroidiye bağlı kaslarda görülen psödohipertrofi oldukça nadir görülen bir klinik tablodur ve Kocher-Debre-Semelaigne sendromu olarak bilinir. Burada boy kısalığının tetkiki için başvuran, 13 yaş 4 aylık kız olguda tespit edilen tiroid aplazisine bağlı hipotiroidi nedeniyle oluşan psödohipertrofiyi vurgulayarak, tedavi edilmeyen hipotirodinin miyopati yapıcı etkisine dikkat çekilmek istendi.

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Cite This Article

ŞEN, T. A., DEMİR, T., KÖKEN, R., MELEK, H., GÜRAKSIN, Ö., UÇAR, H., GÜN, G., ALPAY, F. (2022). Hypothyroidism and muscle pseudohypertrophy: Kocher-debre semelaigne syndrome. Güncel Pediatri, Cilt: 7 - Sayı: 1, 37–40. https://ajindex.com/articles/528100

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