Journals / Güncel Pediatri / 2010 / Cilt: 8 - Sayı: 1

Serum magnesium level and its relation with insulin resistance in obese children

Obez çocuklarda serum magnezyum düzeyinin insülin direnci ile olan ilişkisi

Pages
24–29
Publication Date
2022-10-18
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We compared the differences in between obese and lean groups with Student’s t-test and Pearson’s correlation analysis was used to compare the variables.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Introduction: To determine the relation of serum magnesium level with metabolic and clinical parameters in obese children.
📊
Key Findings & Data:Materials and Methods: Children presenting with weight gain whose BMI was over 95th percentile (obese children) and children with BMI lower than 85th percentile (non-obese) were included to the study.
💡
Conclusion & Impact:We compared the differences in between obese and lean groups with Student’s t-test and Pearson’s correlation analysis was used to compare the variables.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Introduction: To determine the relation of serum magnesium level with metabolic and clinical parameters in obese children. Materials and Methods: Children presenting with weight gain whose BMI was over 95th percentile (obese children) and children with BMI lower than 85th percentile (non-obese) were included to the study. Taking drugs or having a history or evidence of chronic diseases, syndromal or endocrine causes of obesity were excluded. Weight and height were measured for comparing the anthropometric values. For laboratory evaluation, fasting serum glucose, insulin, lipid profile and serum magnesium levels were measured. We compared the differences in between obese and lean groups with Student’s t-test and Pearson’s correlation analysis was used to compare the variables. The value of p

Özet

Giriş: Obez çocuklarda serum magnezyum düzeyinin metabolik (lipid profili, glukoz, insülin, insülin direnç indeksi) ve antropometrik parametreler (VKİ, VKİ SDS) ile olan ilişkisini ortaya koymak. Gereç ve Yöntem: Çalışmaya, kilo artışı şikayeti ile başvuran vücut kitle indeks (VKİ) persentili 95 p üzerinde olan (obez çocuklar) ve VKİ persentili 0,05). Sonuç: Bu çalışma literatürdeki veriler ile benzer şekilde obez çocuklarda serum magnezyum düzeyinin sağlıklı çocuklara göre düşük olduğunu desteklemektedir. Ancak bu çalışmada serum magnezyum düzeyi ile insülin direnci ve lipid profilleri arasında anlamlı korelasyon gösterilememiştir. Sonuç olarak, düşük magnezyum düzeyi ile ilişkili komplikasyonların önlenmesi için obez çocuklar yeterli miktarlarda magnezyum tüketmelidirler.

🔖

Cite This Article

KARAKUŞ, N., KOÇAK, M., RAZİ, C. H., HIZLI, Ş., AKIN, O., ÖZDEMİR, O., ABACI, A. (2022). Serum magnesium level and its relation with insulin resistance in obese children. Güncel Pediatri, Cilt: 8 - Sayı: 1, 24–29. https://ajindex.com/articles/528069

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (18)

  1. Çoban E, Yılmaz A, Sarı R. The effect of weight loss on the mean platelet volume in obese patients. Platelets 2007;18:212-6
  2. Ebbeling CB, Pawlak DB, Ludwig DS. Childhood obesity: public-health crisis, common sense cure. Lancet 2002;360:473-82
  3. Spiotta RT, Luma GB. Evaluating obesity and cardiovascular risk factors in children and adolescents. Am Fam Physician 2008;78:1052-8
  4. Haslam DW, James WP. Obesity. Lancet 2005;366:1197-209
  5. Paolisso G, Barbagallo M. Hypertension, diabetes mellitus, and insulin resistance: the role of intracellular magnesium. Am J Hypertens 1997;10:346-55
  6. Takaya J, Higashino H, Kobayashi Y. Intracellular magnesium and insulin resistance. Magnes Res 2004;17:126-36
  7. Elin RJ. Magnesium metabolism in health and disease. Dis Mon 1988;34:161-218
  8. Guerrero-Romero F, Rodriguez-Moran M. Low serum magnesium levels and metabolic syndrome. Acta Diabetol 2002;39:209-13
  9. Tosiello L. Hypomagnesemia and diabetes mellitus. A review of clinical implications. Arch Intern Med 1996; 156:1143-8
  10. Sales CH, Pedrosa LF. Magnesium and diabetes mellitus: their relation. Clin Nutr 2006;25:554-62
  11. Huerta MG, Roemmich JN, Kington ML, Bovbjerg VE, Weltman AL, Holmes VF et al. Magnesium deficiency is associated with insulin resistance in obese children. Diabetes Care 2005;28:1175-81
  12. Lima ML, Cruz T, Rodrigues LE, Bomfim O, Melo J, Correia R et al. Serum and intracellular magnesium deficiency in patients with metabolic syndrome-evidences for its relation to insulin resistance. Diabetes Res Clin Pract 2009;83:257-62
  13. Nadler JL, Buchanan T, Natarajan R, Antonipillai I, Bergman R, Rude R. Magnesium deficiency produces insulin resistance and increased thromboxane synthesis. Hypertension 1993;21:1024-9
  14. National Center for Health Statistics-CDC Growth Charts: UnitedStates, 2002 [article online]. Available from
  15. Bundak R, Furman A, Gunoz H, Darendeliler F, Bas F, Neyzi O. Body mass index references for Turkish children. Acta Paediatr 2006;95:194-8
  16. American Academy of Pediatrics. National Cholesterol Education Program: Report of the Expert Panel on Blood Cholesterol Levels in Children and Adolescents Pediatrics 1992;89: 525-84
  17. Genuth S, Alberti KG, Bennett P, Buse J, Defronzo R, Kahn R, et al. Follow-up report on the diagnosis of diabetes mellitus. Diabetes Care 2003;26:3160-7
  18. Valerio G, Licenziati MR, Iannuzzi A, Franzese A, Siani P, Ric