Journals / Göztepe Tıp Dergisi / 2003 / Cilt: 18 - Sayı: 3

The relation of the grade of hepatic steatosis with the risk factors and its association with cholelithiasis

Hepatik steatoz derecesinin risk faktörleri ile ilişkisi ve kolelitiasis birlikteliği

Pages
132–134
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

There was no relationship between age and sex of the patient, the duration of and the treatment modality used for diabetes and the presence of hypertension, but it was shown that as the BMI increases, the grade of steatosis also increases (p

📌 3 Key Takeaways

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Objective & Hypothesis:The risk factors for hepatic steatosis and the factors which increases the grade of steatosis still remain unclear.
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Key Findings & Data:In this study, the relationship between the grade of hepatic steatosis, which was detected by ultrasonographic examination, and age, sex, body mass index (BMI) of the patient, presence of hypertension, hyperlipidemia, daibetes mellitus, the duration and the treatment modality used for diabetes, the liver function tests and the presence of cholelithiasis were evaluated. 136 patients admitted to our hospital between April 2000-December 2001, who were diagnosed as having hepatosteatosis by ultrasonographic examination but without a history of alcohol intake and with negative HCV and HBSAg by serological test were included in the study.
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Conclusion & Impact:There was no relationship between age and sex of the patient, the duration of and the treatment modality used for diabetes and the presence of hypertension, but it was shown that as the BMI increases, the grade of steatosis also increases (p
🔬Design:Research Article
📍Scope:2000 Verileri
⚙️Variables:Domain Parameters

Abstract

The risk factors for hepatic steatosis and the factors which increases the grade of steatosis still remain unclear. In this study, the relationship between the grade of hepatic steatosis, which was detected by ultrasonographic examination, and age, sex, body mass index (BMI) of the patient, presence of hypertension, hyperlipidemia, daibetes mellitus, the duration and the treatment modality used for diabetes, the liver function tests and the presence of cholelithiasis were evaluated. 136 patients admitted to our hospital between April 2000-December 2001, who were diagnosed as having hepatosteatosis by ultrasonographic examination but without a history of alcohol intake and with negative HCV and HBSAg by serological test were included in the study. Data were evaluated retrospectively. 68 patients were male (50 %, mean age: 48.5±11.7 years), 68 were female (50 %, mean age: 56.6±9.2 years). The patients with diabetes were grouped according to the duration of diabetes. Hepatic steatosis was graded according to ultrasonographic appearance. Chi-square and anova tests were used for the statistical analysis of datas. There was no relationship between age and sex of the patient, the duration of and the treatment modality used for diabetes and the presence of hypertension, but it was shown that as the BMI increases, the grade of steatosis also increases (p

Özet

Hepatik steatoz için risk faktörleri ve derecesini artıran faktörler halen net olarak bilinmemektedir. Bu çalışmada, ultrasonografik olarak steatoz derecesi belirlenen hastalarda, steatoz derecesi ile yaş, cinsiyet, vücut kitle indeksi (VKİ), hipertansiyon, hiperlipidemi ve diyabet varlığı, diyabetin süresi ve kullanılan tedavi metodu, karaciğer fonksiyon testleri arasında bir ilişki olup olmadığı ve kolelitiasis birlikteliği araştırıldı.Çalışmaya, Nisan 2000-Aralık 2001 tarihleri arasında hastanemizde ultrasonografik incelemede steatoz tanısı alan, alkol alım öyküsü olmayan ve HCV ve HBS Ag negatif olan 136 hasta alındı. Veriler retrospektif olarak incelendi. Hastaların 68'i erkek (% 50, yaş ortalaması: 48.5±11.7), 68'i kadındı (% 50, yaş ortalaması: 56.6±9.2). Diyabeti olan hastalar diyabet süresine göre gruplandırıldı. Hepatik steatoz ultrasonografik görünümüne göre evrelendirildi. Verilerin istatistiksel analizi ki-kare ve anova testleri ile yapılmıştır. Hastanın yaşı, cinsiyeti, diyabet süresi ve kullandığı tedavi yöntemi ve hipertansiyon varlığının steatoz derecesi ile ilişkili olmadığı, fakat artan VKI ile steatoz evresinin de arttığı gösterilmiştir (p< 0.05). Lipid düzeyleri, transaminaz, LDH, GGT düzeyleri ve kolelitiasis varlığı ile steatoz derecesi arasında bir ilişki bulunamadı. Sonuç olarak, steatoz için majör bir risk faktörü olduğu bilinen obesite, steatoz derecesini de etkileyen bir faktördür ve steatoz tedavisi için en etkili yöntem kilo vermektir. Steatoz olgularında kesin prognostik faktörler halen tam olarak açıklanamadığından, karaciğer biyopsisi hastaların değerlendirilmesi ve takibinde altın standard özelliğindedir.

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Cite This Article

YÜCEL, A., DEMİR, S. (2022). The relation of the grade of hepatic steatosis with the risk factors and its association with cholelithiasis. Göztepe Tıp Dergisi, Cilt: 18 - Sayı: 3, 132–134. https://ajindex.com/articles/526471

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