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Journals / GORM:Gynecology Obstetrics & Reproductive Medicine / 1998 / Cilt: 4 - Sayı: 1

Predictive value of serum Ca 15-3 levels in gynecologic neoplasms

Jinekolojik tümörlerde serum Ca 15-3 düzeylerinin predüktif önemi

Uğur SAYGILI
Oktay ERTEN
Alev USLU
Erbil DOĞAN
Turhan USLU
Pages
40–44
Publication Date
2022-10-17
DOI
—
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Serum CA 15-3 and CA 125 values of malignant ovarian neoplasms were higher than those of the benign group, and the difference was statistically significant (P

📌 3 Key Takeaways

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Objective & Hypothesis:OBJECTIVE: To investigate the predictive value of CA 15-3 and CA 125 in the management of gynecologic malignancies MATERIALS AND METHODS: Serum levels of CA 15-3 and CA 125 were measured in 55 patients with a gynecologic neoplasm of which 35 were malignant (13 epithelial ovarian cancer, 11 cervix cancer, 10 endometrium cancer, and 1 vulvar cancer) and 20 were benign.
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Key Findings & Data:Cut -off values for CA 15-3 was taken as 30U/mL. and 60U/mL. ; for CA 125 it was taken as 35U/mL. and 50U/mL .
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Conclusion & Impact:Serum CA 15-3 and CA 125 values of malignant ovarian neoplasms were higher than those of the benign group, and the difference was statistically significant (P
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

OBJECTIVE: To investigate the predictive value of CA 15-3 and CA 125 in the management of gynecologic malignancies MATERIALS AND METHODS: Serum levels of CA 15-3 and CA 125 were measured in 55 patients with a gynecologic neoplasm of which 35 were malignant (13 epithelial ovarian cancer, 11 cervix cancer, 10 endometrium cancer, and 1 vulvar cancer) and 20 were benign. Cut -off values for CA 15-3 was taken as 30U/mL. and 60U/mL. ; for CA 125 it was taken as 35U/mL. and 50U/mL . Sensitivity, specificity, positive and negative predictive values for each of the cut-off value are calculated. RESULTS: The mean values of CA 15-3 were 41.3 ± 8.4 and 20.2 ± 3.5 for malignant and benign tumors, respectively. Serum CA 15-3 and CA 125 values of malignant ovarian neoplasms were higher than those of the benign group, and the difference was statistically significant (P

Özet

OBJECTIVE: To investigate the predictive value of CA 15-3 and CA 125 in the management of gynecologic malignancies MATERIALS AND METHODS: Serum levels of CA 15-3 and CA 125 were measured in 55 patients with a gynecologic neoplasm of which 35 were malignant (13 epithelial ovarian cancer, 11 cervix cancer, 10 endometrium cancer, and 1 vulvar cancer) and 20 were benign. Cut -off values for CA 15-3 was taken as 30U/mL. and 60U/mL. ; for CA 125 it was taken as 35U/mL. and 50U/mL . Sensitivity, specificity, positive and negative predictive values for each of the cut-off value are calculated. RESULTS: The mean values of CA 15-3 were 41.3 ± 8.4 and 20.2 ± 3.5 for malignant and benign tumors, respectively. Serum CA 15-3 and CA 125 values of malignant ovarian neoplasms were higher than those of the benign group, and the difference was statistically significant (P

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Cite This Article

SAYGILI, U., ERTEN, O., USLU, A., DOĞAN, E., USLU, T. (2022). Predictive value of serum Ca 15-3 levels in gynecologic neoplasms. GORM:Gynecology Obstetrics & Reproductive Medicine, Cilt: 4 - Sayı: 1, 40–44. https://ajindex.com/articles/525871

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