Journals / GORM:Gynecology Obstetrics & Reproductive Medicine / 2016 / Cilt: 22 - Sayı: 1

Meigs' Syndromes with Extremelly High CA125 Level Mimicking Advanced Ovarian Cancer

Pages
42–44
Publication Date
2022-10-17
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Despite the suggestion of ovarian malignancy in preoperative period, the frozen/section examination is the mainstay in the management of adnexal masses.

📌 3 Key Takeaways

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Objective & Hypothesis:Meigs' syndrome is defined as pelvic mass with ascites and pleural effusion which can mimic ovarianmalignancy.
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Key Findings & Data:Additionally, elevated serum CA125 level can be seen in Meigs' syndrome.
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Conclusion & Impact:Despite the suggestion of ovarian malignancy in preoperative period, the frozen/section examination is the mainstay in the management of adnexal masses.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Meigs' syndrome is defined as pelvic mass with ascites and pleural effusion which can mimic ovarianmalignancy. Additionally, elevated serum CA125 level can be seen in Meigs' syndrome. We present 2cases with solid adnexal mass, ascites and bilateral pleural effusion with high serum CA125 level (2824IU/mL and 1400 IU/mL) which were diagnosed as ovarian malignancy preoperatively. In both cases levelof CA125 were extremely high for Meigs' syndrome and high level of CA125 in Meigs' Syndrome is unusual. Solid adnexal mass and serous ascites was detected in explorative laparotomy in 2 cases also.Other genital and abdominal structures were normal. In both cases the right salpingo-oophorectomy wasperformed. In addition, the ovarian fibroma was reported in one case and nonspecific for other case during frozen/section examination. Contralateral salpingo-oophorectomy and total hysterectomy was performed because of the age of patients in one case and non- diagnostic frozen section examination inthe other case. Final pathology confirmed the diagnosis of ovarian fibroma in first case and thecoma inthe second one. Despite the suggestion of ovarian malignancy in preoperative period, the frozen/section examination is the mainstay in the management of adnexal masses.

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Cite This Article

KOÇAK, Ö., KARALÖK, A., ÜREYEN, I., TÜRKMEN, O., KOÇ, S., YIRCI, B., KARAKAYA, K. N., TAŞÇI, T., TULUNAY, G., TURAN, T. (2022). Meigs' Syndromes with Extremelly High CA125 Level Mimicking Advanced Ovarian Cancer. GORM:Gynecology Obstetrics & Reproductive Medicine, Cilt: 22 - Sayı: 1, 42–44. https://ajindex.com/articles/525851

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