Journals / Geriatri / 2001 / Cilt: 4 - Sayı: 2

Relationship between age and carotid artery intima-media thickness, hemoglobin A1c in nondiabetic, healthy geriatric population

Nondiyabetik, sağlıklı geriatrik olgularda yaşla, karotid arter intima-media kalınlığı ve hemoglobin A1c arasındaki ilişki

Journal
Geriatri
Pages
63–68
Publication Date
2022-10-17
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Comperative studies done with the elderly who do not benefit from preventive health care prog-rams are needed.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The aims of our study were to investigate the casual relationship between age and carotid artery intima-media thickness (IMT) and hemoglobin A1c (HbA1c) levels and to assess the effects of possible risk factors in healthy nondiabetic elderly. 72 healthy, well-educated, nondiabetic elderly over age of 65 (65-86, mean age was 71.50 ± 5.01) admitted to GATA Geriatric Outpatient Unit for follow-up.
📊
Key Findings & Data:All subjects underwent a comprehensive assessment including a battery of psychosocial and functional performance tests.
💡
Conclusion & Impact:Comperative studies done with the elderly who do not benefit from preventive health care prog-rams are needed.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The aims of our study were to investigate the casual relationship between age and carotid artery intima-media thickness (IMT) and hemoglobin A1c (HbA1c) levels and to assess the effects of possible risk factors in healthy nondiabetic elderly. 72 healthy, well-educated, nondiabetic elderly over age of 65 (65-86, mean age was 71.50 ± 5.01) admitted to GATA Geriatric Outpatient Unit for follow-up. All subjects underwent a comprehensive assessment including a battery of psychosocial and functional performance tests. In addition, also all were asked about health prevention topics including exercise, dietary habits, smoking, vaccination, cholesterol screening etc.. Carotid artery IMT was measured by ultrasonography. Blood samples were obtained for fasting glucose, HbA1c, cholesterol, triglyceride and fibrinogen. Mean carotid artery IMT was 0.94 ± 0.13 mm and mean HbA1c le-vels was 5.29 ± 0.65 mg/dl. We found no significant correlation between age and carotid artery IMT (R= 0.06935), HbA1c levels (R= -0.04776) and other possible atherosclerosis risk factors. Also there was no correlation between carotid artery IMT and HbA1c levels (R= -0.009711). Our study showed that preventive health care measures and risk factor modification is important and must be improved in the elderly age group. Comperative studies done with the elderly who do not benefit from preventive health care prog-rams are needed.

Özet

Sağlıklı nondiyabetik yaşlılarda, yaşla karotid arter intima-media (İM) kalınlığı ve hemoglobin A1c (HbA1c) düzeyleri arasındaki ilişkiyi araştırmak ve muhtemel risk faktörlerinin etkilerini ortaya koymak.GATA Geriatri Polikliniği'ne kontrol amaçlı başvuran, 72 sağlıklı, eğitim düzeyi yüksek, nondiyabetik yaşlı bireyler (65-86, ortalama yaş: 71.50 ± 5.01). Tüm olgular psikososyal ve fonksiyonel performans testlerini de içeren çok yönlü geriatrik değerlendirmeye tabi tutuldu. Aynı zamanda, egzersiz, yeme alışkanlıkları, sigara kullanımı, aşılama, kolesterol taraması gibi koruyucu sağlık hizmetleri ile ilgili konular da sorgulandı. Karotid arter İM kalınlığı ultrasonografi ile ölçüldü. Açlık kan glukozu, HbA1c, kolesterol, trigliserid, fibrinojen tayini için kan örnekleri alındı.Olgularda, ortalama karotid arter İM kalınlığı 0.94 ± 0.13 mm ve ortalama HbA1c düzeyi 5.29 ± 0.65 mg/dl olarak tespit edildi. Yapılan istatistiki değerlendirmede yaşla, karotid arter İM kalınlığı (R= 0.06935) ve HbA1c düzeyleri (R= -0.04776) ve diğer muhtemel ateroskleroz risk faktörleri arasında anlamlı bir ilişki bulunamadı. Aynı zamanda, karotid arter İM kalınlığı ile HbA1c düzeyleri arasında da anlamlı bir korelasyon mevcut değildi (R= -0.009711). Çalışmamız, geriatrik yaş grubunda da koruyucu sağlık hizmetlerinin önemini ve geliştirilmesi gerekliliğini vurgulamaktadır. Ancak, koruyucu sağlık hizmetlerinden faydalanmayan yaşlı hasta grupları ile karşılaştırmalı çalışmalara ihtiyaç vardır.

🔖

Cite This Article

DORUK, H., ATEŞKAN, Ü., SAĞLAM, M., KUTLU, M., MAS, M. R. (2022). Relationship between age and carotid artery intima-media thickness, hemoglobin A1c in nondiabetic, healthy geriatric population. Geriatri, Cilt: 4 - Sayı: 2, 63–68. https://ajindex.com/articles/525202

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (11)

  1. Arnetz BR, Kallner A. Theorell T: The influence of aging on hemoglubin A1c (HbA1c). J. Gerontol. 1982, 37:203-211
  2. Blankenhorn DH, Hodis HN: Arterial imaging and arheroscle-rosis reversal. Arterioscler. Thromb. 1994, 14: 177-19 3. Bond MG, Barnes RW. Riley WA, Wilmoth SK. Chambless LE, Howard G. Owens B: High-resolotion B-mode ultrasound scanning methods in the ARIC cohort: The ARIC Study Group J, Neuroimag. 1991, 1: 68-73 4. Ebrahim S, Papacosta O, Whincup P, Wannamethee G, Walker M, Nicolaides AN, Dhanjil S, Griffin M, Bekam G, RumIey A, Lowe GDO: Carotid plaque, intima media thickness, cardiovascular risk factors, and prevalent cardiovascular disease in men and women: The British Regional H cart Study. Stroke 1999, 30:841-850 5. Fabris F, Zanacchi M, Bo M, Fonte G, Fiandra U, Poli L: Risk factors for atherosclerosis and aging. Int. Angiol. 1994. 13: 52-58 6. Hashimoto Y, Futamura A. Ikushima M: Effect of aging on HbA1c in a working male Japanese population. Diabetes Care 1995, 18:1337-1340
  3. Hatemi H, Ömer A: Proteinlerin glikozillenmesi ve diabetes mellitustaki önemi. Pusula 2 1996:1-31
  4. Hazzard WR: Athcroselerosis and aging: A seenario in flux. Am. J. Cardiol. 1989; 2:20-24
  5. Hodis HN, Mack WJ: Risk factor assestment, treatment strategy and prevention of coronary artery disease: The need for a more rational approach. J. Intern. Med. 1994: 236:111-113
  6. Hudis HN, Mack WJ, LaBree L, Selzer RH, Liu C, Liu C, Azen SP: The role of carotid arterial intima-media thickness in pre-dicting clinical coronary events. Ann. Intern. Med. 1998; 128:262-269
  7. Kabadi UM: Glycosylation of proteins: Lack of influence of aging. Diabetes Care 1988; 11: 429-432
  8. Mannami T, Konishi M. Baba S, Nishi N, Terao A: Prevalence of asymtomatîc carotid atherosclerotic lesions detected by high-resolution ultrasonography and its relatîon to cardiovascular risk factors in the general population of a Japanese City: The Suita Study. Stroke 1997. 28:518-525
  9. Margiti SE, Bund MG. Crouse JR, Furberg CD, Probstfield JL: Progression and regression of carotid atherosclerosis in clinical trials. Atherosclerosis 1991; 11:443-451
  10. Marcus RA, Mack WJ, Azen SP, Hodis HN: İnfluence of lifestyle modification on atherosclerotic progression determined by ultrasonographic change in the common carotid intîma-media thickness. Am. J. Hin. Nutr. 1997; 65:1000-1004
  11. Meigs JB, Nathan DM, Cupples LA, Wilson PWF, Singer De: Tracking of glycated hemoglobin in the original