The IR spectra (υ, cm−1) were viewed with a Perkin-Elmer 1600 FTIR spectrometer inKBr pellets.
📌 3 Key Takeaways
🎯
Objective & Hypothesis:A series of Schiff base ligands containing 1,2,4-triazole ring were obtained by the addition ofaldehydes to the amino compound under mild conditions in 80–82% yields.
📊
Key Findings & Data:New ligands wereinvestigated for their antioxidant activities such as DPPH (2,2-diphenyl-1-picrylhydrazyl), ABTS(2,2’-azino-bis (3-ethylbenzo-thizoline-6-sulphonic acid) diammonium salt) radical scavengingand reducing power. 1H and 13C-NMR spectra (δ, ppm) were observed on a Varian Mercury 200MHz spectrophotometer as standard substance using tetramethylsilane Match constants (Jvalues) were given as Hertz.
💡
Conclusion & Impact:The IR spectra (υ, cm−1) were viewed with a Perkin-Elmer 1600 FTIR spectrometer inKBr pellets.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters
Abstract
A series of Schiff base ligands containing 1,2,4-triazole ring were obtained by the addition ofaldehydes to the amino compound under mild conditions in 80–82% yields. A reduction of theseligands with sodium borohydride resulted in Schiff base reduction products. New ligands wereinvestigated for their antioxidant activities such as DPPH (2,2-diphenyl-1-picrylhydrazyl), ABTS(2,2’-azino-bis (3-ethylbenzo-thizoline-6-sulphonic acid) diammonium salt) radical scavengingand reducing power. 1H and 13C-NMR spectra (δ, ppm) were observed on a Varian Mercury 200MHz spectrophotometer as standard substance using tetramethylsilane Match constants (Jvalues) were given as Hertz. NMR coefficients are truncated as follows: s=singlet, d=dublet,t=triplet, m=multiplet signal. Combustion analysis was performed on a Carlo Erba 1106 elementalanalyzer. All the compounds gave C, H, and N analysis results within ±0.6 % of the theoreticalvalues. The IR spectra (υ, cm−1) were viewed with a Perkin-Elmer 1600 FTIR spectrometer inKBr pellets.
🔖
Cite This Article
GUMRUKCUOGLU, N., SOKMEN, B. B. (2022). Synthesis of New Ligands Containing Azomethine Group and Investigation of Antioxidant, Antiurease Activities. Gazi University Journal of Science, Cilt: 33 - Sayı: 3, 662–671. https://ajindex.com/articles/521287
Carter, M.J., Rillema, D.P., Basolo, F.J., “Oxygen carrier and redox properties of some neutral cobalt chelates. Axial and in-plane ligand effects”, Am. Chem. Soc., 96: 392-400, (1974).
Asada, H., Hayashi, K., Negoro, S., Fujiwara, M., Matsushita, T., “Preparation and structures of tri nuclear manganese (II) complexes with N-2-pyridiylmethylidene-2-hydroxy-5-substitutedphenylamine”, Inorg. Chem. Commun., 6: 193-196, (2003).
Saghatforoush, L., Aminkhani, A., Ershad, S., Karimnezhad, G., Ghammamy, S., Kabiri, R., “Preparation of Zinc (II) and Cadmium (II) Complexes of the Tetradentate Schiff Base Ligand 2-((E)- (2-(2-(pyridine-2-yl)-ethylthio)ethylimino)methyl)-4-bromophenol (PytBrsalH)”, Molecules, 13: 804- 811, (2008).
Li, S., Chen, S., Ma, H., Yu, R., Liu, D.,“Investigation on some Schiff bases as HCl corrosioninhibitors for copper”, Corros. Sci., 41: 1273-1287, (1999).
Khalifa, K.M., Maihub, A.A., El-Ajaily, M.M., Mobain, S.A., “Coordination Trends of 6-Amino-4- hydroxy-2-mercaptopyrimidine Towards Co (II), Ni (II) and Cu (II) Ions”, J. Chem. Soc. Pak., 32: 650- 653, (2010).
Unaleroglu, C., Temelli, B., Hokelek, T., “Conformational and structural analysis of N-N′-bis(4- methoxybenzylidene)ethylenediamine”, J. Mol. Struct., 570: 91-95, (2001).
Barba, V., Santillan, R., Farfan, N., “Dimeric Boronates Derived from the Reaction of Schiff Bases and Boronic Acids”, J. Braz. Chem. Soc., 16: 449-455, (2005).
Chen, W., Ou, W., Wang, L., Hao, Y., Cheng, J., Li, J., Liu, Y.N., “Synthesis and biological evaluation of hydroxyl-substituted Schiff-bases containing ferrocenyl moieties”, Dalton Trans. 42: 15678-15686, (2013).
Norman, D.W., Edwards, J.P., Vogels, C.M., Decken, A.S., Westcott, A., “Synthesis and reactivity of novel Schiff bases containing boronate esters”, Can. J. Chem., 80: 31-40, (2002).
Singh, R.V., Biyala, M.K., “Structural studies with antimicrobial and antifertility activity of a monofunctional bidentate ligand with its boron(III), palladium(II), and platinum(II) complexes”, Phosphorus Sulfur Silicon Relat. Elem., 181: 1477-1491, (2006).
Hou, A., Zhang, C., Wang, Y., “Preparation and UV-protective properties of functional cellulose fabrics based on reactive azobenzene Schiff base derivative”, Carbohydr. Polym., 87: 284-288, (20