Journals / Gazi Medical Journal / 2001 / Cilt: 12 - Sayı: 2

Nitric oxide level of aqueous humour after photorefractive keratectomy in Guinea pigs

Pages
55–58
Publication Date
2022-10-19
DOI
—
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Conclusion: Excimer laser keratectomy did not change the NO level of aqueous humour in guinea pigs 24 hours following photoablation and this finding could be explained by increased transforming growth factor-$beta$1, (TGF-$beta$1) level of aqueous humour after excimer laser therapy.

📌 3 Key Takeaways

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Objective & Hypothesis:To investigate the level of nitric oxide (NO) in aqueous humour after excimer laser keratectomy in guinea pigs.
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Key Findings & Data:Group I served as control, 10 m$mu$ excimer laser corneal photoablation was performed in Group II and 20 m$mu$l corneal photoablation in Group III.
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Conclusion & Impact:Conclusion: Excimer laser keratectomy did not change the NO level of aqueous humour in guinea pigs 24 hours following photoablation and this finding could be explained by increased transforming growth factor-$beta$1, (TGF-$beta$1) level of aqueous humour after excimer laser therapy.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

To investigate the level of nitric oxide (NO) in aqueous humour after excimer laser keratectomy in guinea pigs. Methods: NO levels of the aqueous humour were measured by nitric oxide analyser with chemiluminescence assay in three Groups. Group I served as control, 10 m$mu$ excimer laser corneal photoablation was performed in Group II and 20 m$mu$l corneal photoablation in Group III. Results: NO levels of all groups showed no difference when compared to the control (p>0.05). Conclusion: Excimer laser keratectomy did not change the NO level of aqueous humour in guinea pigs 24 hours following photoablation and this finding could be explained by increased transforming growth factor-$beta$1, (TGF-$beta$1) level of aqueous humour after excimer laser therapy.

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Cite This Article

YİS, Ö., BİLGİHAN, A., BİLGİHAN, K., HASANREİSOĞLU, B., ERBAŞ, D. (2022). Nitric oxide level of aqueous humour after photorefractive keratectomy in Guinea pigs. Gazi Medical Journal, Cilt: 12 - Sayı: 2, 55–58. https://ajindex.com/articles/520615

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