Journals / Gazi Medical Journal / 2016 / Cilt: 27 - Sayı: 2

Hemolitik Anemi Nedeniyle Oluşan Çok Düşük HbA1c Düzeyi

Extraordinarily Low Level of HbA1c due to Hemolytic Anemia

Pages
76–77
Publication Date
2022-10-19
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Herein, we report a very rare clinical presentation of a case of geriatric male patient with an extraordinarily low level of HbA1c (2.7%) which was caused by immune hemolytic anemia associated with chronic lymphocytic leukemia.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:HbA1c measurement gives us information about glycemic levels in patients with diabetes mellitus for the last 3 months.
📊
Key Findings & Data:Some factors such as drugs, anemia (hemolytic anemia, hemoglobinopathies etc.), alcoholism, renal failure may affect HbA1c levels via decreasing erythrocyte survival.
💡
Conclusion & Impact:Herein, we report a very rare clinical presentation of a case of geriatric male patient with an extraordinarily low level of HbA1c (2.7%) which was caused by immune hemolytic anemia associated with chronic lymphocytic leukemia.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

HbA1c measurement gives us information about glycemic levels in patients with diabetes mellitus for the last 3 months. Some factors such as drugs, anemia (hemolytic anemia, hemoglobinopathies etc.), alcoholism, renal failure may affect HbA1c levels via decreasing erythrocyte survival. Herein, we report a very rare clinical presentation of a case of geriatric male patient with an extraordinarily low level of HbA1c (2.7%) which was caused by immune hemolytic anemia associated with chronic lymphocytic leukemia.

Özet

HbA1c ölçümü diyabetik hastalarda son 3 ay içerisindeki kan glukoz düzeyleri hakkında bize fikir vermektedir. İlaçlar, anemi (hemolitik anemi, hemoglobinopatiler vs.), alkolizm ve böbrek yetmezliği gibi bazı durumlar eritrosit yaşam süresini kısaltarak HbA1c düzeylerini etkileyebilmektedir. Burada, çok nadir görülen bir olguyu, kronik lenfositik lösemi ile ilişkili immün hemolitik anemi nedeniyle meydana gelen çok düşük HbA1c düzeyi görülen (%2,7) yaşlı bir erkek hastayı sunuyoruz.

🔖

Cite This Article

SUMER, F., KİLİC, M. K., ULGER, Z., CİVELEK, R., KİZİLARSLANOGLU, M. C. (2022). Hemolitik Anemi Nedeniyle Oluşan Çok Düşük HbA1c Düzeyi. Gazi Medical Journal, Cilt: 27 - Sayı: 2, 76–77. https://ajindex.com/articles/519954

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (7)

  1. Mcdonald MJ, Shapiro R, Bleichman M, Solway J, Bunn HF. Glycosylated minor components of human adult hemoglobin. Purification, identification, and partial structural analysis. J Biol Chem 1978; 253: 2327-32.
  2. Bry L, Chen PC, Sacks DB. Effects of hemoglobin variants and chemically modified derivatives on assays for glycohemoglobin. Clin Chem 2001; 47: 153-63.
  3. Unnikrishnan R, Anjana RM, Jayashri R, Mohan V. Unexpectedly low HbA1c levels in two diabetes patients following dapsone use. Indian J Endocrinol Metab 2012; 16: 658-9.
  4. Albright ES, Ovalle F, Bell DS. Artificially low hemoglobin A1c caused by use of dapsone. Endocr Pract 2002; 8: 370-2.
  5. Fluckiger R, Woodtli T, Berger W. Quantitation of glycosylated hemoglobin by boronate affinity chromatography. Diabetes 1984; 33: 73-6.
  6. Panzer S, Kronik G, Lechner K, Bettelheim P, Neumann E, Dudczak R. Glycosylated hemoglobins (GHb): an index of red cell survival. Blood 1982; 59: 1348-50.
  7. Levitan EB, Liu S, Stampfer MJ, Cook NR, Rexrode KM, Ridker PM, Buring JE, Manson JE. HbA1c measured in stored erythrocytes and mortality rate among middle-aged and older women. Diabetologia 2008; 51: 267-75. Wiener K. A falling HbA1c is not necessarily an indicator of improving diabetes control. Ann Clin Biochem 2001; 38: 406-7.