Journals / Gaziantep Medical Journal / 2015 / Cilt: 21 - Sayı: 1

Tiroid disfonksiyonlu hastalarda HbA1c düzeyleri

The levels of HbA1c in p atients w ith thyroid dysfunction

Pages
5–8
Publication Date
2022-10-18
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

HbA1c leve ls were significantly higher inhyperthyroid group when compared to hypothyroid and euthyroid groups (p

📌 3 Key Takeaways

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Objective & Hypothesis:Thyroid hormones increase the hepatic glyconeogenesis, glycogenolysis and the absorption of glucose.
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Key Findings & Data:HbA1c is the most important determinant of long term glysemicstatus in diabetic patients.
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Conclusion & Impact:HbA1c leve ls were significantly higher inhyperthyroid group when compared to hypothyroid and euthyroid groups (p
🔬Design:Research Article
📍Scope:2009 Verileri
⚙️Variables:Domain Parameters

Abstract

Thyroid hormones increase the hepatic glyconeogenesis, glycogenolysis and the absorption of glucose. Glucoseintolerance is common in thyroid dysfunction. HbA1c is the most important determinant of long term glysemicstatus in diabetic patients. HbA1c is affected from various factors. In this study we evaluated the relationbetween thyroid function tests and HbA1c in non - diabetic patients with thyro id dy sfunction. Non -diabetic 43patients with hyperthyroidism, 20 patients with hypothyroidism and for control group 29 euthyroid p atientswhich appealed to Ankara Numune Training and Research Hospital Internal Outpatient Clinic between June2008 and January 2009 were recruited to this study. Fasting blood sugar, urea, creatinine, hemoglobine,HbA1c, TSH, FT3, FT4 and albumin e levels of all of the patients that recruited to study were determined. Therewas no statistically significant difference for the mean age (p=0.271) and gender distribution (p=0.23) in thecases of hyperthyroidism, hypothyroidism and euthyroid controls. HbA1c leve ls were significantly higher inhyperthyroid group when compared to hypothyroid and euthyroid groups (p

Özet

Tiroid hormonları hepatikglukoneogenezi, glikojenolizi ve intestinal glukoz emilimini arttırırlar. Tiroiddisfonksiyonunda glukoz intoleransı sıkça karşılaşılan bir durumdur. HbA1c diyabetik hastalarda uzun süreliglisemik durumun değerlendirilmesinde en önemli belirteçdir. HbA1c düzeyi ise çeşitli faktörlerdenetkilenebilmektedir. Biz bu çalışmamızda diyabetik olmayan yeni tanı konmuş tedavi almamış tiroiddisfonskiyonu olan hastalarda tiroid fonksiyon testleri ve HbA1c arasındaki ilişkiyi inceledik. Bu çalışmaAnkara Numune Eğitim ve Araştırma Hastanesi Dahiliye polikliniklerine (2008 Haziran -2009 Ocak) başvurandiyabetik olmayan ve ilk kez tanı alan 43 hipertiroidi ve 20 hipotiroidi hastası yla 29 ötiroidili kontrol grubuarasında yapıldı. Çalışmaya katılan tüm olguların açlık kan şekeri, üre, kreatinin, hemoglobin, HbA1c, TSH, FT3,FT4, albümin değerlerine bakıldı. Hipertiroidi, hipotiroidi ve ötiroidi olguların yaş ortalamaları (p = 0,271) vecinsiyet dağılımları (p=0,23) açısından istatiski olarak anlamlı fark bulunmadı. Hipertiroidi grubunda HbA1cseviyesi hipotiroidi ve ötiroid i gruplarına göre istatistiki olarak anlamlı derecede yüksekti.(p

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Cite This Article

TAM, A. A., ÜÇLER, R., ESKİOĞLU, E., BALKAN, F., USLUOĞULLARI, C. A., TAM, H., DEDE, İ., KAYA, C. (2022). Tiroid disfonksiyonlu hastalarda HbA1c düzeyleri. Gaziantep Medical Journal, Cilt: 21 - Sayı: 1, 5–8. https://ajindex.com/articles/518587

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