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Journals / Fiziksel Tıp ve Rehabilitasyon Bilimleri Dergisi / 2017 / Cilt: 20 - Sayı: 3

Successful Management of Gait and Balance Disorder in Hereditary Spastic Paraparesis with an Intrathecal Baclofen Infusion: Case Report

Herediter Spastik Paraparezide Yürüme ve Denge Bozukluğunun İntratekal Baklofen İnfüzyonu ile Başarılı Tedavisi

Mehmet AĞIRMAN
Mustafa Yemliha AYHAN
İlknur SARAL
Oğuz DURMUŞ
Engin ÇAKAR
Pages
146–149
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This report shares a case that was unresponsive tovarious antispastic treatments, but showed marked improvement in the gait disorder with a reducedfall risk after administering an intrathecal baclofen infusion with a pump.

📌 3 Key Takeaways

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Objective & Hypothesis:Hereditary spastic paraparesis (HSP) is a genetic disorder that causes a gait disorderwith spasticity and weakness of the lower extremities.
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Key Findings & Data:The treatment goal is symptomatic: to improve the spasticity and gait disorderand to increase the patient’s quality of life.
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Conclusion & Impact:This report shares a case that was unresponsive tovarious antispastic treatments, but showed marked improvement in the gait disorder with a reducedfall risk after administering an intrathecal baclofen infusion with a pump.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Hereditary spastic paraparesis (HSP) is a genetic disorder that causes a gait disorderwith spasticity and weakness of the lower extremities. HSP causes marked disability and substantialsocioeconomic losses. The treatment goal is symptomatic: to improve the spasticity and gait disorderand to increase the patient’s quality of life. For the symptomatic treatment of HSP, oralantispastic medications, botulinum toxin injections, physical therapy, and surgery can be useful,but there is no consensus on the ideal therapy. This report shares a case that was unresponsive tovarious antispastic treatments, but showed marked improvement in the gait disorder with a reducedfall risk after administering an intrathecal baclofen infusion with a pump.

Özet

Herediter spastik paraparezi, alt ekstremitelerde spastisite ve güçsüzlüğe neden olan genetik bir bozukluktur. Önemli oranda dizabiliteye ve sosyoekonomik kayıplara neden olmaktadır. Tedavinin hedefi; spastisiteyi azaltmak, yürüme bozukluğunu düzeltmek ve hastanın yaşam kalitesini artırmaktır. HSP’nin semptomatik tedavisinde oral antispastik medikasyonlar, botulinum toksin enjeksiyonu, fizik tedavi ve cerrahi faydalı olabilmektedir, ancak tedavisi üzerinde hâlen konsensüs sağlanamamıştır. Bu çalışmada; çeşitli antispastik tedavilere yanıt vermeyen, ancak intratekal baklofen pompası uygulamasından sonra yürüme bozukluğunda ve düşme riskinde anlamlı iyileşme olan bir olgunun sunulması amaçlanmıştır.

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Cite This Article

AĞIRMAN, M., AYHAN, M. Y., SARAL, İ., DURMUŞ, O., ÇAKAR, E. (2022). Successful Management of Gait and Balance Disorder in Hereditary Spastic Paraparesis with an Intrathecal Baclofen Infusion: Case Report. Fiziksel Tıp ve Rehabilitasyon Bilimleri Dergisi, Cilt: 20 - Sayı: 3, 146–149. https://ajindex.com/articles/516821

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References (10)

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