Journals / Fiziksel Tıp ve Rehabilitasyon Bilimleri Dergisi / 2020 / Cilt: 23 - Sayı: 1

A Cross-Sectional Assessment of Neuropathic Pain in Patients with Psoriasis and Psoriatic Arthritis

Psöriyazis ve Psöriyatik Artritte Ağrının Nöropatik Bileşeni: Kesitsel Bir Çalışma

Pages
1–6
Publication Date
2022-10-18
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

However, no association was found between disease severityand neuropathic pain.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Many patients with psoriasis (Ps) and psoriatic arthritis (PsA) develop a variety of sensory skin symptoms as discomfort, burning, stinging, irritation and hypersensitivity.
📊
Key Findings & Data:This study aims to assess the prevalence of NP in patients with Ps and PsA and to investigate the association between disease severity and pain scores.Material and Methods: We conducted a cross-sectional study on 79 Ps patients, 21 PsA patients, and 45 healthy individuals.
💡
Conclusion & Impact:However, no association was found between disease severityand neuropathic pain.
🔬Design:Survey & Empirical Study
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Many patients with psoriasis (Ps) and psoriatic arthritis (PsA) develop a variety of sensory skin symptoms as discomfort, burning, stinging, irritation and hypersensitivity. We hypothesize that neuropathic pain (NP) is a component of these sensory skin symptoms. This study aims to assess the prevalence of NP in patients with Ps and PsA and to investigate the association between disease severity and pain scores.Material and Methods: We conducted a cross-sectional study on 79 Ps patients, 21 PsA patients, and 45 healthy individuals. NP was assessed by the PainDETECT Questionnaire (PDQ). Pain intensity was scored on Visual AnalogueScales (VAS). We used the Psoriasis Area Severity Index (PASI) andthe Dermatology Life Quality Index (DLQI) and Nottingham HealthProfile (NHP) to assess the disease severity and quality of life, respectively.Results: PsA patients had significantly more “likely neuropathic pain” compared with Ps patients and healthy controls (19% vs. 3.8% and 6.7%). The mean PDQ scores were higher in the Ps and PsA groups than the control group. PsA group had significantly worse scores of pain, physical activity, and fatigue compared withthe Ps group. Conclusion: Our findings suggest that neuropathic painmay be a component of the sensory symptoms manifested in PsA patients. However, no association was found between disease severityand neuropathic pain.

Özet

Psöriyazis (Ps) ve psöriyatik artrit (PsA) olan birçok hastada, ciltte rahatsızlık, yanma, acı, tahriş ve aşırı duyarlılık gibi çeşitli duyusal cilt semptomları gelişebilir ve nöropatik ağrı bu duyusal cilt semptomlarının bir bileşeni olabilir. Bu çalışma, Ps ve PsA hastalarında nöropatik ağrı varlığını değerlendirmeyi ve hastalık şiddeti ile ağrı skorları arasındaki ilişkiyi araştırmayı amaçlamaktadır. Gereç ve Yöntemler: Çalışmaya 79 Ps, 21 PsA hastası ve 45 sağlıklı kontrol alındı. Nöropatik ağrı PainDETECT anketi [PainDETECT Questionnaire (PDQ)] ile, ağrışiddeti Görsel Analog Skala [Visual Analog Scale (VAS)] ile değerlendirildi. Hastalık şiddeti ve yaşam kalitesini değerlendirmek için sırasıyla Psöriyazis Alan Ciddiyeti İndeksi (PASI) ,Dermatoloji Yaşam Kalitesi İndeksi (DLQI) ve Nottingham Sağlık Profili (Nottingham Health Profile (NHP) kullanıldı.Bulgular: PsA’lı hastalarda, Ps’li hastalar ve sağlıklı kontrollerle karşılaştırıldığında anlamlı olarak daha yüksek “muhtemel nöropatik ağrı” değerleri izlendi (sırasıyla; %19, %3,8 ve %6,7). Ortalama PDQ skorları Ps ve PsA gruplarında kontrol grubuna göre daha yüksek bulundu. PsA grubu, Ps grubuna göre anlamlı derecede kötü ağrı, fiziksel aktivite ve yorgunluk skorlarına sahipti. Sonuç: Bulgularımız nöropatik ağrının PsA hastalarında ortaya çıkan duyusal semptomların bir bileşeni olabileceğini düşündürmektedir. Bununla birlikte, psöriyazis hastalık şiddeti ve nöropatik ağrı arasında bir ilişki bulunamadı.

🔖

Cite This Article

GÜLER, T., ASLAN, N., DÖRTBAŞ, F., ÇİMEN, Y. G. (2022). A Cross-Sectional Assessment of Neuropathic Pain in Patients with Psoriasis and Psoriatic Arthritis. Fiziksel Tıp ve Rehabilitasyon Bilimleri Dergisi, Cilt: 23 - Sayı: 1, 1–6. https://ajindex.com/articles/516782

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (12)

  1. Ozkaya DB, Onsun N, Topukçu B, et al. The relationship between body mass index, waist circumference and psoriatic arthritis in the Turkish population. Postepy Dermatol Alergol. 2016
  2. [Crossref] [PubMed] [PMC] 2. Choi JW, Kim BR, Seo E, et al. Could psoriatic arthritis be easily diagnosed from current suspicious physical findings in the dermatology clinic? Ann Dermatol. 2017
  3. [Crossref] [PubMed] [PMC] 3. Ljosaa TM, Stubhaug A, Mork C, et al. Improvement in psoriasis area and severity index score predicts improvement in skin pain over time in patients with psoriasis. Acta Derm Venereol. 2013
  4. [Crossref] [PubMed] 4. Ljosaa TM, Mork C, Stubhaug A, et al. Skin pain and skin discomfort is associated with quality of life in patients with psoriasis. J Eur Acad Dermatol Venereol. 2012
  5. [Crossref] [PubMed] 5. Ljosaa TM, Rustoen T, Mørk C, et al. Skin pain and discomfort in psoriasis: an exploratory study of symptom prevalence and characteristics. Acta Derm Venereol. 2010
  6. [Crossref] [PubMed] 6. Moverley AR, Vinall-Collier KA, Helliwell PS. It’s not just the joints, it’s the whole thing: Qualitative analysis of patients’ experience of flare in psoriatic arthritis. Rheumatology (Oxford). 2015
  7. [Crossref] [PubMed] 7. Treede RD, Jensen TS, Campbell JN, et al. Neuropathic pain: redefinition and a grading system for clinical and research purposes. Neurology. 2008
  8. [Crossref] [PubMed] 8. van Laarhoven AI, Kraaimaat FW, WilderSmith OH, et al. Sensitivity to itch and pain in patients with psoriasis and rheumatoid arthritis. Exp Dermatol. 2013
  9. [Crossref] [PubMed] 9. Gölge UH, Şen HM, Kuyucu E, et al. Investigation of knee pain in osteoarthritic and neuropathic pain awareness.Acta Orthop Belg. 2015
  10. [PubMed] 10. Spahr N, Hodkinson D, Jolly K, et al. Distinguishing between nociceptive and neuropathic components in chronic low back pain using behavioural evaluation and sensory examination. Musculoskelet Sci Pract. 2017
  11. [Crossref] [PubMed] [PMC] 11. Rifbjerg-Madsen S, Wæhrens EE, Danneskiold-Samsøe B, et al. Psychometric properties of the painDETECT questionnaire in rheumatoid arthritis, psoriatic arthritis and spondyloarthritis: Rasch analysis and test-retest reliability. Health Qual Life Outcomes. 2017
  12. [Crossref] [PubMed] [PMC] 12. von Elm E, Altman DG, Egger M, et al. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines f