Journals / Fırat Üniversitesi Sağlık Bilimleri Tıp Dergisi / 2011 / Cilt: 25 - Sayı: 1

Erkeklerde kemik mineral dansite belirteçleri

Predictors of bone mineral density in men

Pages
33–38
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

We suggest that all of these parameters must be taken into account during the evaluation of diagnosis of osteoporotic patients.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: It is well known that men loose bone density with aging and are at risk for osteoporosis.
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Key Findings & Data:One-hundred and ninety-three aged men between 35-65 years were evaluated.
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Conclusion & Impact:We suggest that all of these parameters must be taken into account during the evaluation of diagnosis of osteoporotic patients.
🔬Design:Survey & Empirical Study
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: It is well known that men loose bone density with aging and are at risk for osteoporosis. The risk factors for osteoporosis in men remain controversial. The objective of the study is to assess determinants of bone mineral density (BMD) in middle aged Turkish men. Materials and Methods: A cross-sectional study was conducted. One-hundred and ninety-three aged men between 35-65 years were evaluated. Bone density was measured using dual-energy Xray absorptiometry (DEXA). Patients were interviewed using a questionnaire which included variables such as age, weight, height, formal education status, co-morbidity that might cause osteoporosis and as well as for malignancy or rheumatological or neurological diseases, and medications that affect bone metabolism (anticonvulsants, diuretics, thyroid hormone, corticosteroids, heparin, warfarin, methotrexate, and cyclosporine), smoking history, physical activity and calcium intake. Results: According to the lumbar BMD values, 33.7% of them were osteoporotic. According to the hip BMD values, only 13% of were within osteoporotic range. Regression analysis indicated that calcium and alcohol consumption, smoking history, testosterone and cholesterol levels were significant predictors of hip and lumbar bone mineral density. We found a negative correlation between bone loss and calcium, alcohol consumption, testosterone and cholesterol levels. A positive correlation was found between smoking history and osteoporosis. Conclusion: Smoking is one of the major causes of bone loss in Turkish males. We suggest that all of these parameters must be taken into account during the evaluation of diagnosis of osteoporotic patients.

Özet

Amaç: Erkeklerin yaşlanmakla kemik yoğunluklarının azaldığı ve osteoporoz açısından risk altında oldukları iyi bilinmektedir. Erkeklerde osteoporoz için risk faktörleri halen tartışmalıdır. Bu çalışmanın amacı orta yaşlı Türk erkeklerinde kemik mineral yoğunluğu (KMY) belirleyicilerinin değerlendirilmesidir. Gereç ve Yöntem: Kesitsel bir çalışma yapılmıştır. Yüz doksan üç, 35-65 yaş arasında erkek değerlendirilmiştir. Kemik yoğunlukları dual-enerji X-ray absorpsiyometri (DEXA) kullanılarak ölçüldü. Hastalar, yaş, boy, kilo, eğitim durumu, osteoporoza neden olabilecek malignansi, nörolojik, romatolojik hastalıklar gibi komorbidite ve kemik metabolizmasını etkileyen ilaçlar (antikonvülzanlar, diüretikler, tiroid hormonu, kortikosteroidler, heparin, varfarin, metotreksat ve siklosporin), sigara öyküsü, fiziksel aktivite ve kalsiyum alımını içeren bir anket kullanılarak görüşülmüştür. Bulgular: Lomber KMY değerlerine göre, % 33.7’si osteoporotikti. Kalça KMY değerlerine göre, sadece % 13’ü osteoporotik sınırlar içinde idi. Regresyon analizinde kalsiyum ve alkol tüketimi, sigara öyküsü, testosteron ve kolesterol düzeyleri kalça ve lomber kemik mineral yoğunluğunun anlamlı bir yordayıcısı olduğunu göstermiştir. Kemik kaybı ve kalsiyum, alkol tüketimi, testosteron ve kolesterol düzeyleri arasında negatif korelasyon bulundu. Sigara öyküsü ve osteoporoz arasında positif bir korelasyon saptandı. Sonuç: Sigara, Türk erkeklerinde kemik kaybının önemli nedenlerinden biridir. Biz tüm bu parametrelerin osteoporotik hastalarının tanı değerlendirmesi sırasında dikkate alınması gerektiğini önermekteyiz.

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Cite This Article

ÇAKCI, A., İKBAL, K. K., HEKİMOĞLU, B., BAŞARAN, A., KUTSAL, Y. G. (2022). Erkeklerde kemik mineral dansite belirteçleri. Fırat Üniversitesi Sağlık Bilimleri Tıp Dergisi, Cilt: 25 - Sayı: 1, 33–38. https://ajindex.com/articles/514728

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References (18)

  1. Campion JM, Maricic MJ: Osteoporosis in men. Am Fam Physician 2003; 67: 1521-1526
  2. Lane NE: Epidemiology, etiology, and diagnosis of osteoporosis. Am J Obstet Gynecol 2006; 194: 3-11
  3. Kanis JA: Diagnosis of osteoporosis. Osteoporos Int 1997; 7: 108-116
  4. Khosla S, Amin S, Orwoll E: Osteoporosis in men. Endocr Rev 2008; 29: 441-464
  5. Izumotani K, Hagiwara S, Izumotani T, et al: Risk factors for osteoporosis in men. J Bone MinerMetab 2003; 21: 86- 90
  6. Ellen H, Mıller: Osteoporosis is an important public health issue among men, affecting up to 20% of all men in the United States >50 years of age. Vitamin D Insufficiency in Male Osteoporosis Clinical Cornerstone 2006; 8: 14-19
  7. Clarke BL, Ebeling PR, Jones JD, et al: Predictors of bone mineral density in aging healthy men varies by skeletal site. Calcif Tissue Int 2002; 70: 137-145
  8. Krassas GE, Papandrapolou FG, Doukidis D: Age Related In Bone Density Among Healthy Greak Males. J Endocrinal Invest 2001; 24: 326-333
  9. Cankurtaran M, Yavuz BB, Halil M, et al: General characteristics, clinical features and related factors of osteoporosis in a group of elderly Turkish men. Aging Clin Exp Res 2005; 17: 108-115
  10. Nelson DA, Jacobsen G, Barondess DA, Parfitt AM: Ethnic differences in regional bone density, hip axis length, and lifestyle variables among healthy black and white men. J Bone Miner Res 1995; 10: 782-787
  11. Cheung EY, Ho AY, Lam KF, et al: Determinants of bone mineral density in Chinese men. Osteoporos Int 2005; 16: 1481-1486
  12. Toth E, Ferenc V, Meszaros S, et al: Effects of body mass index on bone mineral density in men. Orv Hetil 2005; 146: 1489-1493
  13. Orwoll ES, Bevan L, Phipps KR: Determinants of bone mineral density in older men. Osteoporosis Int 2000; 11: 815-821
  14. Vogel JM, Davis JW, Nomura A, et al: The effects of smoking on bone mass and the rates of bone loss among elderly Japanese-American men. J Bone Miner Res 1997; 12: 1495–1501
  15. Burger H, de Laet CE, van Daele PL, et al: Risk factors for increased bone loss in an elderly population: the Rotterdam study. Am J Epidemiol 1998; 147: 871–879
  16. Ward KD, Klesges RC: A meta-analysis of the effects of cigarette smoking on bone mineral density. Calcif Tissue Int 2001; 68: 259-270
  17. Santori C, Ceccanti M, Diacinti D, et al: Skeletal turnover, bone mineral density, and fractures in male chronic abusers of alcohol. J Endocrinol Invest 2008; 31: 321-326
  18. Turner RT: Skeletal response to alcohol. Alcohol C