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Journals / Fırat Üniversitesi Sağlık Bilimleri Tıp Dergisi / 2016 / Cilt: 30 - Sayı: 1

Applications of Botulinum Toxin in Orofacial Region

Orofasial Bölgede Botulinum Toksin Uygulamaları

Nuray YILMAZ ALTINTAŞ
Ümmügülsüm COŞKUN
Pages
43–49
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

For this reason, this review discusses through the latest literature the historical development structure, the mechanism of action, toxicity, indications, contraindications and side effects of the agent

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Botulinum toxin, the most potent biological toxin, which can be used both for therapeutic as well as for cosmetic purposes in several medical conditions and diseases over the last 30 years.
📊
Key Findings & Data:Although its use has been popular in the field of cosmetic treatment in the recent years, it has also been used by a number of disorders thought to be caused by excess contraction of the muscles.
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Conclusion & Impact:For this reason, this review discusses through the latest literature the historical development structure, the mechanism of action, toxicity, indications, contraindications and side effects of the agent
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Botulinum toxin, the most potent biological toxin, which can be used both for therapeutic as well as for cosmetic purposes in several medical conditions and diseases over the last 30 years. Although its use has been popular in the field of cosmetic treatment in the recent years, it has also been used by a number of disorders thought to be caused by excess contraction of the muscles. In the orofacial region; botulinum toxin has become one of the treatment options in the treatment of many diseases associated with muscles such as temporomandibular joint and salivary gland disorders. For this reason, this review discusses through the latest literature the historical development structure, the mechanism of action, toxicity, indications, contraindications and side effects of the agent

Özet

Botulinum toksini, son 30 yılda tıbbin bir çok dalında ve rahatsızlıkta, hem terapötik hem de kozmetik amaçla kullanılabilen bilinen en güçlü biyolojik toksindir. Her ne kadar son yıllarda kozmetik kullanımı nedeni ile oldukça popüler olsa da, kasların fazla kasılmasının sebep olduğu düşünülen birçok hastalıkta başarılı olarak kullanılmaktadır. Orofasiyal bölgede de; temporomandibular eklem hastalıkları, tükürük bezi hastalıkları gibi kaslar ile ilişkili bir çok rahatsızlığın tedavisinde, botulinum toksin tedavi seçeneklerinin arasına girmiştir. Bu nedenle bu derlemede, botulinum toksinin tarihi gelişimi, yapısı ve etki mekanizması, toksisitesi, endikasyonları, kontraendikasyonları ve yan etkilerine son literatür eşliğinde değinilmiştir

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Cite This Article

ALTINTAŞ, N. Y., COŞKUN, Ü. (2022). Applications of Botulinum Toxin in Orofacial Region. Fırat Üniversitesi Sağlık Bilimleri Tıp Dergisi, Cilt: 30 - Sayı: 1, 43–49. https://ajindex.com/articles/514589

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References (17)

  1. Majid OW. Clinical use of botulinum toxins in oral and maxillofacial surgery. International Journal of Oral and Maxillofacial Surgery 2010; 39: 197-207
  2. Nayyar P, Kumar P, Nayyar PV, Singh A. BOTOX: Broadening the horizon of dentistry. J Clin Diagn Res 2014; 8: ZE25-29
  3. Erbguth FJ, Naumann M. Historical aspects of botulinum toxin: Justinus Kerner (1786-1862) and the "sausage poison". Neurology 1999; 53: 1850-1853
  4. Durmazlar PK. Botulinum toksini (Uygulamaya geçmeden bilinmesi gerekenler). Turkiye Klinikleri J Med Sci 2008; 29: 702-707
  5. Burgen AS, Dickens F, Zatman LJ. The action of botulinum toxin on the neuro-muscular junction. J Physiol 1949; 109: 10-24 6. Tinastepe N, Kucuk BB, Oral K. Botulinum toxin for the treatment of bruxism. Cranio 2015; 33: 291-298
  6. Jankovic J. Botulinum toxin in clinical practice. Journal of Neurology, Neurosurgery, and Psychiatry 2004; 75: 951- 957
  7. Zhou JY, Wang D. An update on botulinum toxin A injections of trigger points for myofascial pain. Current Pain and Headache Reports 2014; 18: 386
  8. Dressler D, Benecke R. Pharmacology of the rapeutic botulinum toxin preparations. Disability and rehabilitation 2007; 29: 1761-1768
  9. Freeman SR, Cohen JL. New neurotoxins on the horizon. Aesthetic Surgery Journal / The American Society for Aesthetic Plastic Surgery 2008; 28: 325-330
  10. Herrero BA, Ecklung AE, Streett CS, Ford DF, King JK. Experimental botulism in monkeys--a clinical pathological study. Experimental and Molecular Pathology 1967; 6: 84- 95
  11. Schantz EJ, Johnson EA. Properties and use of botulinum toxin and other microbial neurotoxins in medicine. Microbiol Rev 1992; 56: 80-99
  12. Kılıç S, Biyolojik Silah Olarak Toksinler. Türk Hij Den Biyol Derg 2006; 63: 85-106 14. Chen YW, Chiu YW, Chen CY, Chuang SK. Botulinum toxin therapy for temporomandibular joint disorders: A systematic review of randomized controlled trials. International Journal of Oral and Maxillofacial Surgery 2015; 44: 1018-1026
  13. Freund B, Schwartz M. The use of botulinum toxin for the treatment of temporomandibular disorder. Oral Health 1998; 88: 32-37
  14. Yalçın S, Aktaş İ. Dişhekimliğinde Temporomandibular Eklem Hastalıklarına Yaklaşım
  15. Baskı, İstanbul: Vestiyer Yayın Grubu; 2010
  16. Freund BJ, Schwartz M. Relief of tension-type headache symptoms in subjects with temporomandibular disorders treated with botulinum toxin-A. Headache 2002; 42: 1033- 1037
  17. De Andres J, Cerda-Olmedo G, Valia JC, et al. Use of botulin