Journals / Fırat Üniversitesi Sağlık Bilimleri Tıp Dergisi / 2017 / Cilt: 31 - Sayı: 3

Death Caused by Anaphylactic Shock After the First Dose of Ceftriaxone Injection: A Case Report

İlk Doz Seftriakson Enjeksiyonu Sonrası Anaflaktik Şok Sonucu Ölüm: Olgu Sunumu

Pages
157–159
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It has been concluded that the timely examining of these markers in patients followed for anaphylaxis is important for determining the cause of death.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Ceftriaxone is a third-generation cephalosporin antibiotic which is often used in the treatment of bacterial infections in clinical practice.
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Key Findings & Data:A 10-year- old boy who has allergic asthma history, was prescribed intramuscular ceftriaxone.
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Conclusion & Impact:It has been concluded that the timely examining of these markers in patients followed for anaphylaxis is important for determining the cause of death.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Ceftriaxone is a third-generation cephalosporin antibiotic which is often used in the treatment of bacterial infections in clinical practice. Anaphylaxis is a rare complication of ceftriaxone. A 10-year- old boy who has allergic asthma history, was prescribed intramuscular ceftriaxone. Anaphylactic shock developed in the patient after the drug was administered in the primary health care center. The patient died after ten days of intensive care unit follow-up. In this study, we presented this case in the light of the literature with pathologic and toxicological examinations performed following forensic autopsy. As a result; markers such as histamine, histaminase and tryptase are considered as indicators of anaphylaxis in the blood. It has been concluded that the timely examining of these markers in patients followed for anaphylaxis is important for determining the cause of death.

Özet

Seftriakson, klinik pratikte bakteriyel enfeksiyonların tedavisinde sıklıkla tercih edilen üçüncü kuşaksefalosporin grubu bir antibiyotiktir. Seftriakson kullanımı sonucu anaflaksi gelişimi nadir görülen birdurumdur. Bu çalışmada alerjik astım öyküsü bulunan 10 yaşındaki erkek çocuğa seftriaksoniçeren bir ilaç reçete edildiği, birinci basamak sağlık merkezinde ilacın uygulanmasından sonraanaflaktik şok gelişen hastanın 10 gün yoğun bakım ünitesinde takip edildikten sonra ölümgörüldüğü, adli otopsinin ardından patolojik ve toksikolojik incelemelerin yapıldığı olgu literatüreşliğinde sunuldu. Sonuç olarak, anaflaksi sebebiyle takip edilen hastalarda kanda anaflaksiningöstergeleri olarak kabul edilen histamin, histaminaz ve triptaz gibi belirteçlerin düzeylerininzamanında incelenmesinin, ölüm nedeninin tespiti açısından önemli olduğu kanaatine varılmıştır.

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Cite This Article

TÜRKOĞLU, A., DEMİR, A., TOKDEMİR, M. (2022). Death Caused by Anaphylactic Shock After the First Dose of Ceftriaxone Injection: A Case Report. Fırat Üniversitesi Sağlık Bilimleri Tıp Dergisi, Cilt: 31 - Sayı: 3, 157–159. https://ajindex.com/articles/514544

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