Journals / Fırat Üniversitesi Sağlık Bilimleri Tıp Dergisi / 2020 / Cilt: 34 - Sayı: 2

Prevalence of Intestinal Protozoan Parasites in Adult Cancer Patients in Elazığ: A Cross-Sectional Study

Elazığ’da Yetişkin Kanser Hastalarındaki Bağırsak Protozoan Parazitlerinin Prevalansı: Kesitsel Bir Çalışma

Pages
97–102
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We think that this area needs more research,which will help clinicians and create new approaches for patients' treatment and follow-up.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Among cancer patients, immunosuppression due to the disease itself or the therapeuticagents used increases the risk of intestinal parasitic infections.
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Key Findings & Data:The aim of the present study was todetermine the types of parasites, the incidence and risk factors that might affect the treatmentprocess and the life quality in cancer patients.Materials and Methods: This study was carried out in Firat University Hospital and 18 years oldand over oncology patients were followed up and treated.
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Conclusion & Impact:We think that this area needs more research,which will help clinicians and create new approaches for patients' treatment and follow-up.
🔬Design:Lab & Field Experiment
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Among cancer patients, immunosuppression due to the disease itself or the therapeuticagents used increases the risk of intestinal parasitic infections. The aim of the present study was todetermine the types of parasites, the incidence and risk factors that might affect the treatmentprocess and the life quality in cancer patients.Materials and Methods: This study was carried out in Firat University Hospital and 18 years oldand over oncology patients were followed up and treated. Stool specimens were taken 3 times (atleast once) on different days from patients and examined primarily by native and lugol methods.Subsequently, preparations prepared by applying the formol-ether concentration method wereexamined by specific staining methods.Results: Among 111 oncology patients, 43 (38.7%) were infected with one or more parasites. In 33(29.7%) patients, a parasite was detected, whereas 7 of them (6.3%) had two species, and 1 ofthem (0.9%) had three species of parasites. Blastocystis sp. was the most common parasiticspecies in 34 (30.6%) cases. Only commensal parasites were detected in 32 (28.8%) stoolspecimens and commensal and pathogenic parasites were detected in 11 (9.9%) stool specimens.There was no significant difference in the distribution of parasitic infections according todemographic characteristics, disease history, personal hygiene habits, clinical status andcomplaints of the patients.Conclusion: The prevalence of intestinal protozoa in our study group is higher than the prevalencedetected in the normal population in our region. We think that this area needs more research,which will help clinicians and create new approaches for patients' treatment and follow-up.

Özet

Amaç: Kanser hastalarında, hastalığın kendisinden veya kullanılan terapötik ajanlardan kaynaklanan immünsüpresyon, intestinal paraziter enfeksiyon riskini arttırır. Bu çalışmada, parazit türlerinin belirlenmesi, insidansı ve risk faktörlerinin belirlenmesi amaçlanmıştır. Gereç ve Yöntem: Bu çalışma Fırat Üniversitesi Hastanesi'nde takip ve tedavi edilen 18 yaş ve üzeri onkoloji hastalarında yapıldı. Hastalardan en az bir kez olmak üzere farklı günlerde 3 kez gaita alındı. Daha sonra, formol-eter konsantrasyon yöntemi uygulanarak hazırlanan preparatlar, özel boyama yöntemleri ile incelenmiştir. Bulgular: 111 onkoloji hastasının 43'ünde (%38.7) bir veya daha fazla parazit mevcuttu. Hastaların 33'ünde (%29.7) bir parazit türü saptanırken, 7'sinde (%6.3) iki tür, 1'inde (%0.9) üç tür parazit vardı. 34 (%30.6) olguda saptanan Blastocystis sp. en sık görülen paraziter türdü. Dışkı örneklerinin 32’sinde (%28.8) sadece kommensal parazitler, 11’inde (%9.9) kommensal ve patojenik parazitler tespit edildi. Paraziter enfeksiyonların demografik özelliklerine, hastalık öyküsüne, kişisel hijyen alışkanlıklarına, klinik durumuna ve hastaların şikayetlerine göre dağılımında anlamlı bir fark bulunamadı. Sonuç: Çalışma grubumuzdaki intestinal protozoaların prevalansı, bölgemizdeki normal popülasyonda tespit edilen prevalanstan daha yüksek olduğu bulunmuştur. Bu alan ile ilgili klinisyenlerin hasta takibi ve tedavisi için yeni yaklaşımlar yaratmasına yardımcı olabilecek daha fazla araştırmaya ihtiyaç duyulduğunu düşünüyoruz.

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Cite This Article

KAPLAN, M., MÜLAYİM, S., KELEŞTEMUR, N., AKSOY, A. (2022). Prevalence of Intestinal Protozoan Parasites in Adult Cancer Patients in Elazığ: A Cross-Sectional Study. Fırat Üniversitesi Sağlık Bilimleri Tıp Dergisi, Cilt: 34 - Sayı: 2, 97–102. https://ajindex.com/articles/514450

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References (12)

  1. Mohammadi-Ghalehbin B, Pezeshki A, Kohansal MH, Esmaeilnezhad G. Frequency of Intestinal Parasites in Patients with Malignancy in Ardabil Province, Northwest Iran. J Hum. Environ. Health Promot 2017; 2: 118-124
  2. Keiser J, Utzinger J. The Drugs we have and the Drugs we need against Major Helminth Infections. Adv Parasit 2010; 73: 197-230
  3. Evering T, Weiss LM. The immunology of parasite infections in immunocompromised hosts. Parasite Immunol 2006; 28: 549-565
  4. Marcos LA, Gotuzzo E. Intestinal protozoan infections in the immunocompromised host. Curr Opin Infect Dis 2013; 26: 295-301
  5. Jeske S, Bianchi TF, Moura MQ, et al. Intestinal parasites in cancer patients in the South of Brazil. Braz J Biol 2018; 78: 574-578 6. Lustigman S, Prichard RK, Gazzinelli A, et al. A research agenda for helminth diseases of humans: The problem of helminthiases. PLoS Negl Trop Dis 2012; 6: e1582
  6. Bundy DA, Hall A, Medley G, Savioli L. Evaluating Measures to Control Intestinal Parasitic Infections. World Health Stat Q 1992; 45: 168-179
  7. Kipyegen CK, Shivairo RS, Odhiambo RO. Prevalence of intestinal parasites among HIV patients in Baringo, Kenya. Pan Afr Med J 2013; 13: 37
  8. Rasti S, Hassanzadeh M, Hooshyar H, et al. Intestinal parasitic infections in different groups of immunocompromised patients in Kashan and Qom cities, central Iran. Scand J Gastroenterol 2017; 52: 738-741 10. Koksal F, Baslanti I, Samasti M. A Retrospective evaluation of the prevalence of intestinal parasites in Istanbul, Turkey. Türkiye Parazitol Derg 2010; 34: 166­171
  9. Tas T, Ayaz E, Kocoglu E, Bucak O, Karabork Ş. The Distribution of Intestinal Parasites Detected in the Abant Izzet Baysal University Medical Faculty Hospital. Abant Medical Journal 2014; 3: 124-127
  10. Pektas B, Aksoy Gokmen A, Inci A, Biten AA, Kesli R. Three years of distribution of intestinal parasites in an Education and Research Hospital: A retrospective study. J Clin Exp Invest (JCEI) 2015; 6: 269-273
  11. Duzyol D, Kilimcioglu AA, Ozyurt BC, Ozkan H, Girginkardeşler N. Incidence of intestinal parasites detected in the Department of Parasitology in Celal Bayar University Hospital between 2006 and 2010. Türkiye Parazitol Derg 2012; 36: 147-151
  12. Turgay N, Unver-Yolasıgmaz A, Oyur T, Bardak-Ozcem S, Toz S. Monthly distribution of intestinal parasites detected in a part of Western Turkey between May 2009- April 2010-Results of acid fast and modified trichrome staining methods. Türkiye Parazitol Derg 2012; 36: