Journals / Fırat Üniversitesi Sağlık Bilimleri Tıp Dergisi / 2021 / Cilt: 35 - Sayı: 1

The Effect of Preemptive Intravenous Ibuprofen onPostoperative Opioid Consumption in Patients for DoubleJaw Surgery: A Randomized Double-blind Placebo ControlledStudy

Çift Çene Cerrahisi Yapılan Hastalarda Preemptif Intravenöz İbuprofenin Postoperatif Opioid Tüketimine Etkisi: Randomize Çift Kör Plasebo Kontrollü Çalışma

Pages
62–67
Publication Date
2022-10-18
DOI
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⚡ TL;DR(Too Long; Didn't Read)

The pain of thegroups was evaluated with Visual Analog Scale (VAS), and the total opioid consumption wasrecorded at the end of 24 hours.Results: VAS scores of the patients were compared with the Control Group, the VAS scores weresignificantly lower in the ibuprofen group at 1st, 2nd, 4th, 8th, 12th and 24th hours (P

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The effect of intravenous ibuprofen preemptively administered in pain managementafter double jaw surgery are limited.The purpose of the present study was to investigate the effectsof preemptive intravenous ibuprofen on postoperative analgesia and opioid consumption in patientswho undergo double jaw surgery (DJS).
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Key Findings & Data:Materials and Methods: After ethical committee approval, 48 patients, American Society ofAnesthesiologist (ASA) I-II, scheduled for DJS were randomly assigned into two groups.
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Conclusion & Impact:The pain of thegroups was evaluated with Visual Analog Scale (VAS), and the total opioid consumption wasrecorded at the end of 24 hours.Results: VAS scores of the patients were compared with the Control Group, the VAS scores weresignificantly lower in the ibuprofen group at 1st, 2nd, 4th, 8th, 12th and 24th hours (P
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: The effect of intravenous ibuprofen preemptively administered in pain managementafter double jaw surgery are limited.The purpose of the present study was to investigate the effectsof preemptive intravenous ibuprofen on postoperative analgesia and opioid consumption in patientswho undergo double jaw surgery (DJS). Materials and Methods: After ethical committee approval, 48 patients, American Society ofAnesthesiologist (ASA) I-II, scheduled for DJS were randomly assigned into two groups. Theibuprofen group (n=24) received 800 mg IV ibuprofen in 100 mL saline, while the control group(n=24) received 100 mL saline, thirty minutes before the surgery. All patients were administered1.000 mg iv paracetamol 30 minutes before the surgery ended and was repeated every 6 hours.Postoperative analgesia was performed with patient controlled analgesia (PCA). The pain of thegroups was evaluated with Visual Analog Scale (VAS), and the total opioid consumption wasrecorded at the end of 24 hours.Results: VAS scores of the patients were compared with the Control Group, the VAS scores weresignificantly lower in the ibuprofen group at 1st, 2nd, 4th, 8th, 12th and 24th hours (P

Özet

Amaç: Preemptif uygulanan intravenöz ibuprofenin çift çene cerrahisi sonrası ağrı yönetimindekirolü ile ilgili bilgi kısıtlıdır. Bu çalışmanın amacı çift çene cerrahisi (ÇÇC) geçiren hastalardapreemptif intravenöz ibuprofenin postoperatif analjezi ve opioid tüketimine etkisini araştırmaktır. Gereç ve Yöntem: Etik kurul onayı alındıktan sonra, ÇÇC planlanan, Amerikan AnesteziyolojiDerneği (ASA) I-II, 48 hasta, rastgele iki gruba ayrıldı. Ameliyattan otuz dakika önce ibuprofengrubu (n=24) 100 mL salin içinde 800 mg IV ibuprofen alırken, kontrol grubu (n=24) 100 mL salinaldı. Tüm hastalar operasyon bitiminden yarım saat önce 1.000 mg parasetamol aldı ve her 6saatte bir tekrarlandı. Postoperatif analjezi hasta kontrollü analjezi (HKA) ile sağlandı. Her ikigrubun ağrısı Vizüel Analog Skala (VAS) ile değerlendirildi ve 24 saat sonunda toplam opioidtüketimleri kaydedildi. Bulgular: VAS skorları kontrol grubuyla karşılaştırıldığında ibuprofen grubunda 1., 2., 4., 8., 12. ve24. saatlerde istatistiksel olarak düşüktür (P

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Cite This Article

YAYIK, A. M., AYDIN, M. E., ERTAŞ, Ü., BEDİR, Z., SALCAN, S., ATEŞ, İ. (2022). The Effect of Preemptive Intravenous Ibuprofen onPostoperative Opioid Consumption in Patients for DoubleJaw Surgery: A Randomized Double-blind Placebo ControlledStudy. Fırat Üniversitesi Sağlık Bilimleri Tıp Dergisi, Cilt: 35 - Sayı: 1, 62–67. https://ajindex.com/articles/514427

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References (13)

  1. Practice guidelines for acute pain management in the perioperative setting: An updated report by the American Society of Anesthesiologists Task Force on acute pain management. Anesthesiology 2012; 116: 248-273
  2. Soper NJ, Stockmann PT, Dunnegan DL, Ashley SW. Laparoscopic cholecystectomy. The new 'gold standard'? Arch Surg 1992; 127: 917-921
  3. Moucha CS, Weiser MC, Levin EJ. Current strategies in anesthesia and analgesia for total knee arthroplasty. J Am Acad Orthop Surg 2016; 24: 60-73
  4. Liu L, Yi J, Wasson MN. Techniques for Preemptive Analgesia in Gynecologic Surgery. J Minim Invasive Gynecol 2019; 26:197
  5. Kien NT, Geiger P, Van Chuong H, et al. Preemptive analgesia after lumbar spine surgery by pregabalin and celecoxib: A prospective study. Drug Des Devel Ther. 2019; 13: 2145-2152
  6. Kim MP, Godoy C, Nguyen DT, et al. Preemptive painmanagement program is associated with reduction of opioid prescriptions after benign minimally invasive foregut surgery. J Thorac Cardiovasc Surg 2020; 159:734-744.e4
  7. Gago Martínez A, Escontrela Rodriguez B, Planas Roca A, Martínez Ruiz A. Intravenous ibuprofen for treatment of post-operative pain: A multicenter, double blind, placebocontrolled, randomized clinical trial. PLoS One 2016; 11: e0154004
  8. Kroll PB, Meadows L, Rock A, Pavliv L. A multicenter, randomized, double-blind, placebo-controlled trial of intravenous ibuprofen (i.v.-ibuprofen) in the management of postoperative pain following abdominal hysterectomy. Pain Pract 2011; 11: 23-32
  9. Moss JR, Watcha MF, Bendel LP, et al. A multicenter, randomized, double-blind placebo-controlled, single dose trial of the safety and efficacy of intravenous ibuprofen for treatment of pain in pediatric patients undergoing tonsillectomy. Paediatr Anaesth 2014; 24: 483-4999
  10. Southworth SR, Woodward EJ, Peng A, Rock AD. An integrated safety analysis of intravenous ibuprofen (Caldolor(®)) in adults. J Pain Res 2015; 8:753-765
  11. Cunningham SJ, Garratt AM, Hunt NP. Development of a condition-specific quality of life measure for patients with dentofacial deformity: I. Reliability of the instrument. Community Dent Oral Epidemiol 2000; 28:195-201
  12. Ahiskalioglu A, İnce İ, Aksoy M, et al. Effects of a singledose of pre-emptive pregabalin on postoperative pain and opioid consumption after double-jaw surgery: A Randomized Controlled Trial. J Oral Maxillofac Surg 2016; 74: 53.e1-7
  13. Cillo JE, Jr., Dattilo DJ. Pre-emptive analgesia with pregabalin and celeco