Journals / Fırat Üniversitesi Sağlık Bilimleri Tıp Dergisi / 2021 / Cilt: 35 - Sayı: 1

Can the Triglyceride/HDL Ratio in Chronic Kidney Disease bePredictive of Cardiac Risk?

Kronik Böbrek Hastalığında Trigliserit/HDL Oranı Kardiyak Riskinin Öngördürücüsü Olabilir mi?

Pages
35–39
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

TG/HDL-C ratio was found to behigher in patients with chronic kidney disease that did not undergo dialysis, compared to chronickidney patients undergoing dialysis and the healthy control group.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Chronic Kidney Failure is one of the important causes of increased morbidity andmortality recently.
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Key Findings & Data:In our study, 40 healthy, 50 dialysedpatients with chronic renal failure and 50 patients without receiving dialysis (predialysis) whoapplied to internal medicine outpatient clinic were included.
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Conclusion & Impact:TG/HDL-C ratio was found to behigher in patients with chronic kidney disease that did not undergo dialysis, compared to chronickidney patients undergoing dialysis and the healthy control group.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Chronic Kidney Failure is one of the important causes of increased morbidity andmortality recently. Cardiovascular mortality is an important cause of mortality in patients withchronic kidney failure. It has been reported that triglyceride/high density lipoprotein ratio (TG/HDL) cholesterol ratio shows cardiac risk in previous studies. In our study, we aimed to show whetherthere is a relationship between TG/HDL cholesterol ratio and cardiovascular risk in patients withchronic renal failure receiving dialysis treatment and not. Materials and Methods: A single-center retrospective study. In our study, 40 healthy, 50 dialysedpatients with chronic renal failure and 50 patients without receiving dialysis (predialysis) whoapplied to internal medicine outpatient clinic were included. Patients' files were scannedretrospectively. TG/HDL ratios were recorded and calculated. Patients who use lipid-lowering drugs and patients with diabetes were not included in our study. Results: TG/HDL cholesterol ratio was found to be statistically significantly higher in predialysispatients and patients receiving dialysis due to chronic renal failure compared to healthy controls.TG/HDL cholesterol ratio was higher in patients with chronic renal failure that did not undergodialysis compared to patients with chronic renal failure that were dialysed, but it was not statisticallysignificant. Conclusion: As an indicator of cardiovascular mortality due to chronic kidney disease, theTG/HDL-C ratio can be an inexpensive, reproducible predictor. TG/HDL-C ratio was found to behigher in patients with chronic kidney disease that did not undergo dialysis, compared to chronickidney patients undergoing dialysis and the healthy control group.

Özet

Amaç: Kronik Böbrek Yetmezliği, son zamanlarda artan morbidite ve mortalitenin önemlinedenlerinden biridir. Kardiyovasküler mortalite, kronik böbrek yetmezliği olan hastalarda önemli birölüm nedenidir. Önceki çalışmalarda trigliserid/HDL (TG/HDL) kolesterol oranının kardiyak riskigösterdiği bildirilmiştir. Çalışmada, diyalize girmeyen kronik böbrek yetmezliği ve diyalize girenkronik böbrek yetmezliği hastalarında TG/HDL kolesterol oranı ile kardiyovasküler risk arasında birilişki olup olmadığını göstermeyi amaçlanmıştır. Gereç ve Yöntem: Bu çalışmaya Dahiliye Polikliniği'ne başvuran 40 sağlıklı, 50 diyalizli kronikböbrek yetmezliği hastası ve diyalize girmeyen 50 kronik böbrek hastası dahil edildi. Hastalarındosyaları geriye dönük olarak tarandı. TG/HDL oranları kaydedildi ve hesaplandı. Çalışmada lipid düşürücü ilaç kullanan hastalar ve diyabetli hastalar dahil edilmedi. Bulgular: TG/HDL kolesterol oranı diyaliz öncesi ve kronik böbrek yetmezliği olan hastalardasağlıklı kontrollere göre istatistiksel olarak anlamlı yüksek bulundu. TG/HDL kolesterol oranı, diyalizuygulanmayan kronik böbrek yetmezliği olan hastalarda, diyaliz yapılan kronik böbrek yetmezliğihastalarına göre daha yüksekti, ancak istatistiksel olarak anlamlı değildi. Sonuç: Kronik böbrek hastalığına bağlı kardiyovasküler mortalitenin bir göstergesi olarak,TG/HDL-C oranı ucuz, tekrarlanabilir bir prediktör olabilir. Diyalize giren kronik böbrek hastaları vesağlıklı kontrol grubuna göre diyalize girmeyen kronik böbrek hastalığı olanlarda TG/HDL-C oranıdaha yüksek bulundu.

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Cite This Article

AKTAŞ, A., GEDİKLİ, M. A., KARA, C., BAKIR, M. R. (2022). Can the Triglyceride/HDL Ratio in Chronic Kidney Disease bePredictive of Cardiac Risk?. Fırat Üniversitesi Sağlık Bilimleri Tıp Dergisi, Cilt: 35 - Sayı: 1, 35–39. https://ajindex.com/articles/514401

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