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Journals / Fırat Üniversitesi Sağlık Bilimleri Tıp Dergisi / 2022 / Cilt: 36 - Sayı: 1

Evaluation of Antibody Levels and Certain Biochemical Parameters in the Patients Infected with SARS-COV-2

SARS-COV-2 Enfekte Hastalarda Antikor Düzeyleri ve Bazı Biyokimyasal Parametrelerin Değerlendirilmesi

Özgür ASLAN
Ayser MIZRAKLI
Gülseren SAMANCI AKTAR
Arzu RAHMANALI ONUR
Mehmet Hanifi DURAK
Pages
19–24
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Significant difference was determined between the two groups from the polyclinic and service/intensive care unit in terms of WBC, NEU, RBC and Hb, ferritin, CRP, PCT and D-dimer levels (p= 0.001, 0.007, 0.002, 0.006, 0.001,

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: In cases with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease clinical usefulness of serological tests remains uncertain.
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Key Findings & Data:The study aimed to evaluate anti-SARS- CoV-2 antibody and some biochemical parameters such as leukocyte (WBC), neutrophil (NEU), lymphocyte (LYM), thrombocyte (PLT), erythrocyte (RBC), hemoglobin (Hb), ferritin, procalcitonin (PCT), C-reactive protein (CRP) and D-dimer in the patient specimens sent from the polyclinic and service/intensive care unit.
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Conclusion & Impact:Significant difference was determined between the two groups from the polyclinic and service/intensive care unit in terms of WBC, NEU, RBC and Hb, ferritin, CRP, PCT and D-dimer levels (p= 0.001, 0.007, 0.002, 0.006, 0.001,
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: In cases with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease clinical usefulness of serological tests remains uncertain. The study aimed to evaluate anti-SARS- CoV-2 antibody and some biochemical parameters such as leukocyte (WBC), neutrophil (NEU), lymphocyte (LYM), thrombocyte (PLT), erythrocyte (RBC), hemoglobin (Hb), ferritin, procalcitonin (PCT), C-reactive protein (CRP) and D-dimer in the patient specimens sent from the polyclinic and service/intensive care unit. Materials and Methods: A total of 110 patients’ specimens sent from the polyclinic and from the service/intensive care unit were used. SARS-CoV-2 RT PCR, immunoassay SARS-CoV-2 antibody and other biochemical tests were assessed. Results: Anti-SARS-CoV-2 antibody was positive in 11 (5 polyclinic, 6 service/intensive care) of 24 patients with negative RT-PCR test. Significant difference was determined between the two groups from the polyclinic and service/intensive care unit in terms of WBC, NEU, RBC and Hb, ferritin, CRP, PCT and D-dimer levels (p= 0.001, 0.007, 0.002, 0.006, 0.001,

Özet

Amaç: Ağır akut solunum sendromu korona virus 2 (SARS-CoV-2) hastalığına karşı serolojik testlerin klinik yararlarının belirsizliği devam etmektedir. Çalışmada poliklinik ve servis/yoğun bakımdan gelen hasta numunelerinde SARS-CoV-2 antikor ve WBC, NEU, LYM, PLT, RBC sayısı, Hb miktarı, ferritin, PCT, CRP ve D-dimer gibi bazı biyokimyasal parametrelerin değerlendirilmesi amaçlanmıştır. Gereç ve Yöntem: Çalışmada poliklinik ve servis/yoğun bakımdan gelen toplam 110 hasta numunesi kullanılmıştır. Hastaların SARS-CoV-2 RT-PCR, immunoassay SARS-CoV-2 antikor ve diğer biyokimyasal testleri çalışılmıştır. Bulgular: RT-PCR testi negatif 24 hastanın 11’inde (5 poliklinik, 6 servis/yoğun bakım) Anti-SARS-CoV-2 antikorları pozitif saptanmıştır. WBC, NEU, RBC sayısı, Hb, ferritin, CRP, PCT, D dimer düzeyleri için poliklinik ve servis/yoğun bakımdan gelen iki grup arasında anlamlı farklılık (sırasıyla p= 0.001, 0.007, 0.002, 0.006, 0.001,

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Cite This Article

ASLAN, Ö., MIZRAKLI, A., AKTAR, G. S., ONUR, A. R., DURAK, M. H. (2022). Evaluation of Antibody Levels and Certain Biochemical Parameters in the Patients Infected with SARS-COV-2. Fırat Üniversitesi Sağlık Bilimleri Tıp Dergisi, Cilt: 36 - Sayı: 1, 19–24. https://ajindex.com/articles/514385

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