Journals / Experimental Biomedical Research / 2022 / Cilt: 5 - Sayı: 3

The prognostic value of neutrophil–to-lymphocyte ratio and platelet–to-lymphocyte ratio in the severe COVID-19 cases

Pages
344–350
Publication Date
2022-10-12
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Results: When all the data were analyzed, NLR/PLR and CRP levels were found to be higher at statistically significant levels in the severe patient group than in the control group, and LMR was lower (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: COVID-19 is a cause of high-mortality pandemic with the RNA virus in its etiology and has an effect all over the world.
📊
Key Findings & Data:In the present study, the relationship between in-hospital prognosis and mortality was investigated by comparing neutrophil-to-lymphocyte ratio (NLR), platelet –to-lymphocyte ratio (PLR) values with C-reactive protein (CRP) and with a detailed analysis of complete blood count and biochemical parameters in mild and severe COVID-19 cases.
💡
Conclusion & Impact:Results: When all the data were analyzed, NLR/PLR and CRP levels were found to be higher at statistically significant levels in the severe patient group than in the control group, and LMR was lower (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: COVID-19 is a cause of high-mortality pandemic with the RNA virus in its etiology and has an effect all over the world. In the present study, the relationship between in-hospital prognosis and mortality was investigated by comparing neutrophil-to-lymphocyte ratio (NLR), platelet –to-lymphocyte ratio (PLR) values with C-reactive protein (CRP) and with a detailed analysis of complete blood count and biochemical parameters in mild and severe COVID-19 cases. Method: A total of 271 patients who were diagnosed with pneumonia because of COVID-19 and 278 healthy control groups were included in the study. In our study, COVID-19 cases were divided into 2 groups as mild and severe, and the data were compared with healthy people without COVID-19. Lung tomography results of the cases that were diagnosed with COVID-19 were examined. Those with positive RT-PCR (Real-Time Polymerized Chain Reaction) test results were recorded from the system. Biochemical tests and complete blood count parameters of the patients, NLR/ lymphocyte- to- monocyte ratio (LMR)/PLR N/L, and CRP levels were compared with the control group. The results were evaluated and analyzed in statistical terms. Results: When all the data were analyzed, NLR/PLR and CRP levels were found to be higher at statistically significant levels in the severe patient group than in the control group, and LMR was lower (p

🔖

Cite This Article

TÜMER, M., OTAL, Y., ÇELİK, K. (2022). The prognostic value of neutrophil–to-lymphocyte ratio and platelet–to-lymphocyte ratio in the severe COVID-19 cases. Experimental Biomedical Research, Cilt: 5 - Sayı: 3, 344–350. https://ajindex.com/articles/512581

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (14)

  1. Organization WH. Clinical management of severe acute respiratory infection (SARI) when COVID-19 disease is suspected: interim guidance, 13 March 2020. World Health Organization, 2020. [2]Tao RJ, Luo XL, Xu W, et al. Viral infection in community acquired pneumonia patients with fever: a prospective observational study. J Thorac Dis. 2018
  2. 10(7): 4387–95. [3]Henry BM, Aggarwal G, Wong J, et al. Lactate dehydrogenase levels predict coronavirus disease 2019 (COVID-19) severity and mortality: A pooled analysis. Am J Emerg Med. 2020
  3. 38(9):1722-1726. [4]Guan WJ, Ni ZY, Hu Y, et al. China Medical Treatment Expert Group for Covid-19. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med. 2020
  4. 382 (18):1708–20. [5]Lagunas-Rangel FA. Neutrophil-tolymphocyte ratio and lymphocyte-to-Creactive protein ratio in patients with severe coronavirus disease 2019 (COVID-19): A meta-analysis. J Med Virol. 2020
  5. 92(10):1733-34. [6]Liu Y, Du X, Chen J, et al. Neutrophil-tolymphocyte ratio as an independent risk factor for mortality in hospitalized patients with COVID-19. J Infect. 2020
  6. 81(1):e6-e12. [7]Smilowitz NR, Kunichoff D, Garshick M, et al. C-reactive protein and clinical outcomes in patients with COVID-19. Eur Heart J. 2021
  7. 42(23):2270-79. [8]Fathi N, Rezaei N. Lymphopenia in COVID19: Therapeutic opportunities. Cell Biol Int. 2020
  8. 44(9):1792-97. [9]Seyit M, Avci E, Nar R, et al. Neutrophil to lymphocyte ratio, lymphocyte to monocyte ratio and platelet to lymphocyte ratio to predict the severity of COVID-19. Am J Emerg Med. 2021
  9. Deng Y, Liu W, Liu K, et al. Clinical characteristics of fatal and recovered cases of coronavirus disease 2019 in Wuhan, China: a retrospective study. Chin Med J. 2020:133
  10. Yang AP, Liu JP, Tao WQ, et al. The diagnostic and predictive role of NLR, d-NLR and PLR in COVID-19 patients. Int Immunopharmacol. 2020
  11. 106504. [12]Lissoni P, Rovelli F, Colciago M, et al. Evidence of Abnormally Low LymphocyteTo-Monocyte Ratio In Covid-19-Induced Severe Acute Respiratory Syndrome. J Immuno Allerg. 2020
  12. 1(2):1-6. [13]Zhang H, Cao X, Kong M, et al. Clinical and hematological characteristics of 88 patients with COVID-19. Int J Lab Hematol. 2020
  13. 42(6):780-787. [14]Liu Y, Du X, Chen J, et al. Neutrophil-tolymphocyte ratio as an independent risk factor for mortality in hospitalized patients with COVID-19. J Infect. 2020
  14. 81(1):e6-e12. [15]Shahid MF, Malik A, Siddiqi FA, et al. Neutrophil-to-Lymphocyte Ratio and