Journals / European Journal of General Medicine / 2011 / Cilt: 8 - Sayı: 3

Sirozlu hastalarda otonom nöropatinin renal kan akımı üzerine etkisi

Effects of autonomic neuropathy on renal blood flow in patients with liver cirrhosis

Pages
182–188
Publication Date
2022-10-18
DOI
—
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⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Renal artery and interlobar artery RI increased in cir- rhotic patients compared to controls but no effect of autonomic neu- ropathy was established on renal hemodynamics.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: We evaluated the effect of autonomic neuropathy on renal blood flow in patients with cirrhosis.
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Key Findings & Data:Method: Fifty-nine patients with liver cirrhosis and 45 healthy con- trols were enrolled in the study.
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Conclusion & Impact:Conclusion: Renal artery and interlobar artery RI increased in cir- rhotic patients compared to controls but no effect of autonomic neu- ropathy was established on renal hemodynamics.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: We evaluated the effect of autonomic neuropathy on renal blood flow in patients with cirrhosis. Method: Fifty-nine patients with liver cirrhosis and 45 healthy con- trols were enrolled in the study. The size and parenchymal thickness of both kidneys were measured in all patients and controls. Renal vas- cular resistance indices(RI) of the kidneys were evaluated by Doppler ultrasonography and autonomic neuropathy tests defined by Ewing and Clarke were administered on all patients included in the study. Result: While there was no difference in parenchymal thickness or the size of either kidney between cirrhotic patients and the control group, the renal vascular RI of the renal artery (right kidney 0,70±0,06 vs. 0.61±0.03 and left kidney 0.69±0.06 vs. 0.61±0.03) and interlobar artery (right kidney 0.65±0.06 vs. 0.57±0.04 and left kidney 0.66±0.06 vs. 0.56±0.03) showed significant difference (p 0.05). Similarly, there was no statistically significant difference in any parameter be- tween patients with or without ascites (p> 0.05). Conclusion: Renal artery and interlobar artery RI increased in cir- rhotic patients compared to controls but no effect of autonomic neu- ropathy was established on renal hemodynamics.

Özet

Amaç: Sirozlu hastalarda otonom nöropatinin renal kan akımı üzerine etkilerini araştırmayı amaçladık. Metod: Çalışmaya 59 karaciğer sirozlu hasta ve 45 sağlıklı kontrol alındı. Tüm hastaların ve kontrol grubunun her iki böbrek boyutları ve parankim kalınlıkları ölçüldü. Renal vasküler rezistans indeksleri (Rİ) sağ ve sol böbrekten doppler ultrasonografi ile değerlendirildi ve çalışmaya alınan tüm hastalara Ewing ve Clarke tarafından tanımlanan otonom nöropati testleri yapıldı. Bulgular: Sirotik hastalar ile kontrol grubu karşılaştırıldığında, sırası ile her iki böbrek boyutlarında ve parankim kalınlığında fark yok iken, her iki böbrekten ölçülen renal arter (sağ böbrekten 0,70±0,06 karşılık 0,61±0,03 ve sol böbrekten 0,69±0,06 karşılık 0,61±0,03) ve interlober arter Rİ (sağ böbrekten 0,65±0,06 karşılık 0,57±0,04 ve sol böbrekten 0,66±0,06 karşılık 0,56±0,03) arasında anlamlı fark vardı (p 0.05). Benzer olarak, asiti olan ve olmayan hastalar arasında da bu parametrelerde bir fark yoktu. (p> 0.05). Sonuç: Renal arter ve interlobar arter Rİ kontrol grubuna göre sirotik hastalarda armıştı ama otonom nöropati varlığının renal hemodinamikler üzerine herhangi bir etkisi tesbit edilmedi.

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Cite This Article

YAKAR, T., SAKALLI, H., PAURBAGHER, A., GÜÇLÜ, M. (2022). Sirozlu hastalarda otonom nöropatinin renal kan akımı üzerine etkisi. European Journal of General Medicine, Cilt: 8 - Sayı: 3, 182–188. https://ajindex.com/articles/511135

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