Journals / European Journal of Breast Health / 2018 / Cilt: 14 - Sayı: 1

Characteristics of Special Type Breast Tumors in Our Center

Pages
17–22
Publication Date
2022-10-18
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In order to achieve more significant results, multicenter national studies are needed

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: Breast cancer is a heterogeneous disease with different histological types.
📊
Key Findings & Data:Here in this study, we tried to describe the clinical features of special type breast cancers in our center.Materials and Methods: Retrospective descriptive study was performed in Kocaeli University School of Medicine, Department of General Surgery between January 2000 and January 2016.
💡
Conclusion & Impact:In order to achieve more significant results, multicenter national studies are needed
🔬Design:Research Article
📍Scope:2000 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: Breast cancer is a heterogeneous disease with different histological types. Ductal breast cancer constitutes the vast majority of the breast cancers. However limited data are present in the rest of breast cancers called special or rare type breast cancers. Here in this study, we tried to describe the clinical features of special type breast cancers in our center.Materials and Methods: Retrospective descriptive study was performed in Kocaeli University School of Medicine, Department of General Surgery between January 2000 and January 2016. Women diagnosed with primary breast cancer other than ductal carcinoma were included to the study. In total, 101 patients were evaluated according to histologic types, molecular types, Tumor Node Metastasis (TNM) stages, and grades. Survival of the patients was also evaluated. Results: Medullary and metaplastic types showed basal type; tubular, mucinous, micropapillary carcinoma, cribriform, lobular and apocrine tumors showed luminal type molecular pattern. Neither the existence of ductal carcinoma nor any histologic types had any effects on survival. Apocrine tumors were presented in younger ages. Conclusion: Histologic types of breast cancer are closely related with the molecular types of the breast cancer. Tumor size, grade, stage of the disease can show differences among histological types which might be due to the genetic background, late onset or limited number of patients. In order to achieve more significant results, multicenter national studies are needed

🔖

Cite This Article

ERÇİN, C., BARAN, M. A., TRABZONLU, L., PÖSTEKİ, G., YILMAZ, T. U., UTKAN, Z., GÜLER, S. A. (2022). Characteristics of Special Type Breast Tumors in Our Center. European Journal of Breast Health, Cilt: 14 - Sayı: 1, 17–22. https://ajindex.com/articles/510842

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (1)

  1. Gannon LM, Cotter MB, Quinn CM. The classification of invasive carcinoma of the breast. Expert Rev Anticancer Ther 2013; 13: 941-954. (PMID: 23984896) [CrossRef] 2. Weigelt B, Geyer FFC, Reis-Filho JS. Histological types of breast cancer: How special are they? Mol Oncol 2010; 4: 192-208. (PMID: 20452298) [CrossRef] 3. Eroles P, Bosch A, Perez-Fidalgo A, Lluch A. Molecular biology in breast cancer: Intrinsic subtypes and signaling pathways. Cancer Treat Rev 2012; 38: 698-707. (PMID: 22178455) [CrossRef] 4. Li CI, Uribe DJ, Daling JR. Clinical characteristics of different histological types of breast cancer. Br J Cancer 2005; 93: 1046-1052. (PMID: 22178455) [CrossRef] 21 Yılmaz et al. Special Type Breast Tumors 5. Goldhirsch A, Winer EP, Coates AS, Gelber RD, Piccart-Gebhart M, Thürlimann B, Senn HJ; Panel members. Personalizing the treatment of women with early breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2013. Ann Oncol 2013; 24: 2206-2223. (PMID: 23917950) [CrossRef] 6. Stalsberg H, Thomas DB. Age distribution of histological types of breast carcinoma. Int J Cancer 1993; 54: 1-7. (PMID: 8478135) [CrossRef] 7. Anderson WF, Chu KC, Chang S, Sherman ME. Comparison of age-specific incidence rate patterns for different histopathologic types of breast carcinoma. Cancer Epidemiol Biomarkers Prev 2004; 13: 1128-1135. (PMID: 15247123) 8. Lakhani SR, Gusterson BA, Jacquemier J, Sloane JP, Anderson TJ, van de Vijver MJ, Venter D, Freeman A, Antoniou A, McGuffog L, Smyth E, Steel CM, Haites N, Scott RJ, Goldgar D, Neuhausen S, Daly PA, Ormiston W, McManus R, Scherneck S, Ponder BA, Futreal PA, Peto J, Stoppa-Lyonnet D, Bignon YJ, Stratton MR. The pathology of familial breast cancer: histological features of cancers in families not attributable to mutations in BRCA 1 or BRCA 2. Clin Cancer Res 2000; 6: 782-789. (PMID: 10741697) 9. Weigelt B, Horlings HM, Kreike B, Hayes MM, Hauptmann M, Wessels LF, de Jong D, Van de Vijver MJ, Van't Veer LJ, Peterse JL. Refinement of breast cancer classification by molecular characterization of histological special types. J Pathol 2008; 216: 141-150. (PMID: 18720457) [CrossRef ] 10. Rody A, Holtrich U, Pusztai L, Liedtke C, Gaetje R, Ruckhaeberle E, Solbach C, Hanker L, Ahr A, Metzler D, Engels K, Karn T, Kaufmann M. T-cell metagene predicts a favorable prognosis in estrogen receptornegative and HER2 positive breast cancers. Breast Cancer Res 2009; 11: R15.