Journals / European Journal of Breast Health / 2021 / Cilt: 17 - Sayı: 1

Phyllodes Tumors of the Breast: A Single-Center Experience

Pages
36–41
Publication Date
2022-10-18
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In addition, it should also be consideredthat the contribution of imaging techniques may be limited.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: We aimed to analyze the clinicopathological findings, treatment approach, and treatmen outcomes in patients diagnosed with phyllodes tumor(PT).Materials and Methods: The clinicopathological data of 26 patients with PT, who were treated between 2008 and 2019, were retrospectively analyzed.Results: Mean age was 35.07±13.95 years (range: 14–71), while mean tumor size was 54.76±29.24 mm (range: 25–135).
📊
Key Findings & Data:Benign, borderline, andmalignant PT were detected in 18 (69.2%), 3 (11.5%), and 5 (19.2%) patients, respectively.
💡
Conclusion & Impact:In addition, it should also be consideredthat the contribution of imaging techniques may be limited.
🔬Design:Research Article
📍Scope:2008 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: We aimed to analyze the clinicopathological findings, treatment approach, and treatmen outcomes in patients diagnosed with phyllodes tumor(PT).Materials and Methods: The clinicopathological data of 26 patients with PT, who were treated between 2008 and 2019, were retrospectively analyzed.Results: Mean age was 35.07±13.95 years (range: 14–71), while mean tumor size was 54.76±29.24 mm (range: 25–135). Benign, borderline, andmalignant PT were detected in 18 (69.2%), 3 (11.5%), and 5 (19.2%) patients, respectively. Marginless excision was performed in 20 patients (76.9%),while six (23.1%) patients underwent mastectomy. A statistically significant correlation of tumor type with mean tumor size and mean age was observed(p=0.041 and p=0.013, respectively). Margin positivity on first excision was more frequent in the malignant tumors (p=0.02). No statistically significantcorrelation of PT type with presence of breast cancer in the family history, and tumor localization was observed (p=0.79 and p=0.13, respectively). Meanpostoperative follow-up duration was 56 months (range: 6–147). Local recurrence was not observed in any of the patients. Lung and left vastus lateralismuscle metastases were encountered. The patient with lung metastasis became exitus because of the same reason 6 months after detection of the metastasis.Conclusion: PT is a rare fibroepithelial tumor of the breast that is characterized by a mixed histology seen in younger ages when compared to the classicalbreast tumors. The probability of PT should be considered in the presence of a rapid-growing mass in the breast. In addition, it should also be consideredthat the contribution of imaging techniques may be limited.

🔖

Cite This Article

AYKOTA, M. R., YILMAZ, S., KARAKAYA, Y. A., ÖZGEN, U., ERDEM, E. (2022). Phyllodes Tumors of the Breast: A Single-Center Experience. European Journal of Breast Health, Cilt: 17 - Sayı: 1, 36–41. https://ajindex.com/articles/510720

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (13)

  1. Bernstein L, Deapen D, Ross RK. The descriptive epidemiology of malignant cystosarcoma phyllodes tumors of the breast. Cancer. 1993
  2. (PMID: 8387873) [Crossref ] 2. Reinfuss M, Mituś J, Duda K, Stelmach A, Ryś J, Smolak K. The treatment and prognosis of patients with phyllodes tumor of the breast: an analysis of 170 cases. Cancer 1996
  3. (PMID: 8608483) [Crossref ] 3. Atalay C, Kınaş V, Çelebioğlu S. Analysis of patients with phyllodes tumor of the breast. Turk J Surgery Ulusal Cerrahi Derg 2020
  4. (PMID: 25931913) [Crossref ] 4. Mishra SP, Tiwary SK, Mishra M, Khanna AK. Phyllodes tumor of breast: a review article. ISRN Surg 2013
  5. 361469. (PMID: 23577269) [Crossref ] 5. Zhang Y, Kleer CG. Phyllodes tumor of the breast: histopathologic features, differential diagnosis, and molecular/genetic updates. Arch Pathol Lab Med 2016
  6. (PMID: 27362571) [Crossref ] 6. Li J, Tsang JY, Chen C, Chan SK, Cheung SY, Wu C, et al. Predicting outcome in mammary phyllodes tumors: relevance of clinicopathological features. Ann Surg Oncol 2019
  7. (PMID: 31111353) [Crossref ] 7. Noguchi S, Motomura K, Inaji H, Imaoka S, Koyama H. Clonal analysis of fibroadenoma and phyllodes tumor of the breast. Cancer Res 1993
  8. (PMID: 8395336) [Crossref ] 8. Chen WH, Cheng SP, Tzen CY, Yang TL, Jeng KS, Liu CL, et al. Surgical treatment of phyllodes tumors of the breast: retrospective review of 172 cases. J Surg Oncol 2005
  9. (PMID: 16118768) [Crossref ] 9. Hanby AM, Walker C, Tavassoli FA, Devilee P. Pathology and Genetics: Tumours of the Breast and Female Genital Organs. WHO Classification of Tumours series - volume IV. Lyon, France: IARC Press
  10. Barrio AV, Clark BD, Goldberg JI, Hoque LW, Bernik SF, Flynn LW, et al. Clinicopathologic features and long-term outcomes of 293 phyllodes tumors of the breast. Ann Surg Oncol 2007
  11. (PMID: 17562113) [Crossref ] 11. Ditsatham C, Chongruksut W. Phyllodes tumor of the breast: diagnosis, management and outcome during a 10-year experience. Cancer Manag Res 2019
  12. (PMID: 31695485) [Crossref ] 12. Zhao H, Cheng X, Sun S, Yang W, Kong F, Zeng F. Synchronous bilateral primary breast malignant phyllodes tumor and carcinoma of the breast with Paget’s disease: a case report and review of the literature. Int J Clin Exp Med 2015
  13. 17839-17841. (PMID: 26770378) [Crossref ] 13. Mallory MA, Chikarmane SA, Raza S, Lester S, Cat