Journals / Eurasian Journal of Pulmonology / 2017 / Cilt: 19 - Sayı: 1

How Successful is Non-Invasive Ventilation Treatment that is Initiated in the Emergency Department in Cases of COPD Exacerbations with Acute Hypercapnic Respiratory Failure? Can We Predict Treatment Failure?

Pages
13–18
Publication Date
2022-10-18
DOI
—
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⚡ TL;DR(Too Long; Didn't Read)

Similarly, higher PaCO2 and lower pH values at the end of the first day in wards were indicative of NIV failure (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: We aimed to investigate the success rate of non-invasive ventilation (NIV) in wards and the predictors of failure in cases of chronic obstructive pulmonary disease (COPD)-related acute hypercapnic respiratory failure (AHRF).
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Key Findings & Data:Methods: The was a retrospective study conducted in a tertiary teaching hospital between May 2011 and 2013.
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Conclusion & Impact:Similarly, higher PaCO2 and lower pH values at the end of the first day in wards were indicative of NIV failure (p
🔬Design:Research Article
📍Scope:2011 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: We aimed to investigate the success rate of non-invasive ventilation (NIV) in wards and the predictors of failure in cases of chronic obstructive pulmonary disease (COPD)-related acute hypercapnic respiratory failure (AHRF). Methods: The was a retrospective study conducted in a tertiary teaching hospital between May 2011 and 2013. Patients who were admitted to the emergency department (ED) because of COPD with AHRF were evaluated; 544 patients who initially received NIV in ED and were transferred to wards were included. Patient characteristics, baseline and follow-up pH values, and partial arterial carbon dioxide (PaCO2) values were recorded. Baseline pH values were categorized as severe (pH=7.26-7.30), and mild (pH>=7.30) acidosis. According to the in-hospital outcome, patients were classified in 2 groups: Group 1: home discharge, Group 2: death or intensive care unit transfer. Results: Treatment resulted in success in 477 (88%) patients. Albumin levels were significantly low and the mean Charlson index (CI) score was significantly high in Group 2. Admission pH and PaCO2 values did not affect the treatment outcome. Patients in Group 2 had higher PaCO2 and lower pH values as well as a lower level of decrease in PaCO2 values within 2 hours of treatment in ED. Similarly, higher PaCO2 and lower pH values at the end of the first day in wards were indicative of NIV failure (p

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Cite This Article

ARINÇ, S., SEVİM, T., AKYIL, M., AKYIL, F. T., AĞCA, M. Ç., KOSİF, A. M., DUMAN, D. (2022). How Successful is Non-Invasive Ventilation Treatment that is Initiated in the Emergency Department in Cases of COPD Exacerbations with Acute Hypercapnic Respiratory Failure? Can We Predict Treatment Failure?. Eurasian Journal of Pulmonology, Cilt: 19 - Sayı: 1, 13–18. https://ajindex.com/articles/509698

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References (6)

  1. Global Initiative for Chronic Obstructive Lung Disease [homepage on the Internet]. Global strategy for diagnosis, management, and prevention of COPD [updated 2012]. Available from: http://www.goldcopd.org. Accessed October 5, 2015
  2. Donaldson GC, Wedzicha JA. COPD exacerbations- 1: Epidemiology. Thorax 2006; 61: 164-8. [CrossRef] 3. Schumaker GL, Epstein SK. Managing acute respiratory failure during exacerbation of chronic obstructive pulmonary disease. Respir Care 2004; 49: 766-82
  3. Keenan SP, Sinuff T, Burns K, Muscedere J, Kutsogiannis J, Mehta S, et al. Clinical practice guidelines for the use of noninvasive positive-pressure ventilation and noninvasive continuous positive airway pressure in the acute care setting. CMAJ 2011; 183: 195-214. [CrossRef] 5. Chiumello D, Conti G, Foti G, Giacomini Matteo M, Braschi A, Iapichino G, et al. Noninvasive ventilation outside the intensive care unit for acute respiratory failure. Minerva Anestesiol 2009; 75: 459-66
  4. Demoule A. Noninvasive ventilation: how far away from the ICU? Intensive Care Med 2009; 35: 192-94. [CrossRef] 7. Benoit DD, Depuydt PO. Noninvasive ventilation in patients with hematological malignancies: the saga continues, but where is the finale? Intensive Care Med 2010; 36: 1633-5. [CrossRef] 8. Plant PK, Owen JL, Elliott MW. One year-period prevalence study of respiratory acidosis in acute exacerbations of COPD: implications for the provision of non-invasive ventilation and oxygen administration. Thorax 2000; 55: 550-1. [CrossRef] 9. Celikel T, Sungur M, Ceyhan B, Karakurt S. Comparison of non-invasive positive pressure ventilation with standard medical therapy in hypercapnic acute respiratory failure. Chest 1998; 114: 1636-42. [CrossRef] 10. Brochard L, Mancebo J, Wysocki M, Lofaso F, Conti G, Rauss A, et al. Noninvasive ventilation for acute exacerbations of chronic obstructive pulmonary disease. N Engl J Med 1995; 333: 817-22. [CrossRef] 11. Hill NS. Where should noninvasive ventilation be delivered? Respir Care 2009; 54: 62-9
  5. Wood KA, Lewis L, Von Harz B, Kollef MH. The use of noninvasive positive pressure ventilation in the emergency department: results of a randomized clinical trial. Chest 1998; 113: 1339-46. [CrossRef] 13. Cabrini L, Moizo E, Nicelli E, Licini G, Turi S, Landoni G, et al. Noninvasive ventilation outside the intensive care unit from the patient point of view: a pilot study. Respir Care 2012; 57: 704-9
  6. Fiorino S, Bacchi-Reggiani L, Detotto E, Battilana M,